Chu Ding Technology HPD-25 / GM-0.33A Oil-Free Diaphragm Vacuum Pump for Solvent Filtration Systems
| Brand | Chu Ding Technology |
|---|---|
| Origin | Shanghai, China |
| Model | HPD-25 / GM-0.33A |
| Flow Rate | 25 L/min (HPD-25) / 20 L/min (GM-0.33A) |
| Ultimate Vacuum | −0.08 MPa |
| Power Consumption | 50 W (HPD-25) / 160 W (GM-0.33A) |
| Application | HPLC mobile phase filtration, solid-phase extraction (SPE), degassing, and general laboratory vacuum filtration |
Overview
The Chu Ding Technology HPD-25 and GM-0.33A are compact, oil-free diaphragm vacuum pumps engineered specifically for integration with solvent filtration systems in analytical and preparative laboratories. These pumps operate on the principle of reciprocating elastomeric diaphragm displacement—eliminating the need for lubricating oil and thereby preventing hydrocarbon contamination of sensitive samples or solvents. This design ensures compliance with stringent purity requirements in high-performance liquid chromatography (HPLC), ultra-high-performance liquid chromatography (UHPLC), and pharmaceutical quality control workflows. With a stable ultimate vacuum of −0.08 MPa (equivalent to ~80 kPa absolute pressure), both models provide sufficient suction head for efficient filtration through standard 0.22 µm or 0.45 µm membrane filters used in mobile phase preparation. The HPD-25 delivers 25 L/min free-air flow at ambient conditions, while the GM-0.33A offers 20 L/min with higher motor power (160 W), enabling more consistent performance under backpressure from viscous solvents or clogged membranes.
Key Features
- Oil-free operation using reinforced nitrile rubber diaphragms—ensures zero risk of solvent contamination and eliminates maintenance associated with oil changes or vapor traps
- Robust thermal management system with integrated overheat protection, extending service life during extended filtration cycles
- Low-noise design (<55 dB(A) at 1 m distance), suitable for shared lab environments and ISO Class 5–7 cleanroom-adjacent workspaces
- Compact footprint (HPD-25: 220 × 120 × 180 mm; GM-0.33A: 260 × 140 × 200 mm) optimized for benchtop integration with standard 1000 mL or 2000 mL borosilicate glass filtration assemblies
- Chemically resistant housing and internal wetted parts compatible with common HPLC solvents including acetonitrile, methanol, water, and dilute aqueous buffers (pH 2–10)
- Front-panel on/off switch with LED status indicator and built-in fuse protection (250 V AC, 1 A)
Sample Compatibility & Compliance
These pumps are routinely deployed in GLP- and GMP-aligned laboratories for mobile phase filtration prior to HPLC injection—a critical step referenced in USP , EP 2.2.46, and ICH Q5C guidelines. The absence of oil vapor emission meets ISO 8573-1 Class 0 air purity requirements for instrument-grade vacuum applications. When paired with certified sterile-grade filter membranes (e.g., PVDF or PTFE, 0.22 µm), the system supports aseptic filtration protocols compliant with ASTM F838-22 for bacterial retention validation. The borosilicate glass filtration bottles (not included) referenced in product documentation conform to DIN/ISO 3585 specifications and withstand thermal shock up to ΔT = 270 °C—enabling hot-solvent filtration without risk of fracture.
Software & Data Management
As standalone analog vacuum sources, the HPD-25 and GM-0.33A do not incorporate digital controllers or data logging interfaces. However, they are fully compatible with third-party vacuum monitoring systems (e.g., digital vacuum gauges with 4–20 mA output or RS-485 Modbus RTU) when installed in automated solvent preparation stations. Their stable vacuum output enables reproducible filtration times across batches—a prerequisite for audit-ready SOPs under FDA 21 CFR Part 11 when paired with electronic lab notebooks (ELNs) that record pump activation timestamps and operator IDs.
Applications
- HPLC/UHPLC mobile phase degassing and particulate removal prior to system priming
- Solid-phase extraction (SPE) manifold evacuation for consistent cartridge elution profiles
- Pre-filtration of aqueous standards and calibration solutions in environmental and clinical chemistry labs
- Colloid and nanoparticle suspension clarification in materials science research
- Weighing and microanalysis sample preparation requiring solvent-free vacuum environments
- Support for lyophilization pre-concentration steps where low-level vacuum suffices
FAQ
Can these pumps be used continuously for >8 hours per day?
Yes—provided ambient temperature remains below 35 °C and inlet gas is free of liquid carryover. Continuous operation beyond 8 h/day requires periodic inspection of diaphragm integrity every 500 operating hours.
Is the GM-0.33A suitable for filtering acetonitrile/water mixtures?
Yes. Its chemically inert wetted path (EPDM seals, stainless steel valve plates, and nitrile diaphragm) resists swelling and degradation in common reversed-phase HPLC solvents.
Do these pumps meet CE or UL safety certification?
The HPD-25 and GM-0.33A comply with GB 4706.1-2005 (Chinese national standard equivalent to IEC 60335-1) and carry CCC mark. CE marking is available upon request for EU-distributed units with full EMC and LVD test reports.
What is the expected service life under typical lab use?
With proper handling (no liquid ingress, regular dust filter cleaning), mean time between failures exceeds 10,000 hours for the HPD-25 and 8,500 hours for the GM-0.33A, based on accelerated life testing per ISO 13374-2.
Can I connect this pump directly to a vacuum oven or desiccator?
Not recommended. These models are rated for intermittent duty with maximum continuous vacuum load ≤ 0.06 MPa. For ovens or desiccators requiring sustained deep vacuum, a two-stage rotary vane or scroll pump is advised.
