Labonce Labonce-500MIS Mold Incubator with Humidity Control

Overview

The Labonce Labonce-500MIS Mold Incubator with Humidity Control is a purpose-engineered environmental chamber designed for standardized cultivation of filamentous fungi, yeasts, and other moisture-sensitive microorganisms in regulated laboratory settings. Unlike general-purpose incubators, the Labonce-500MIS integrates tightly coupled temperature and relative humidity (RH) control systems to maintain stable conditions within the biologically critical range of 15–50 °C and 50–85 %RH—parameters aligned with ISO 8513:2017 (microbiological water quality testing), USP and , and APHA Standard Methods for the Examination of Water and Wastewater (BOD₅ and mold enumeration protocols). Its dual-loop PID control architecture ensures dynamic compensation for door openings, load changes, and ambient fluctuations—essential for reproducible fungal sporulation kinetics and colony morphology assessment. The unit complies with IEC 61010-1 safety standards for laboratory equipment and is constructed to support GLP and GMP-aligned workflows in pharmaceutical QC, environmental monitoring, and food safety laboratories.

Key Features

• Stable dual-parameter control: Independent high-precision sensors and proportional-integral-derivative (PID) algorithms regulate both temperature and RH simultaneously, minimizing cross-interference between thermal and humidification subsystems.
• Uniform airflow distribution: A re-engineered horizontal air circulation system—featuring adjustable-speed centrifugal fans and optimized baffle geometry—achieves ≤3.0 °C temperature uniformity across the full 500 L chamber volume at any setpoint.
• Contamination-resistant chamber: Interior surfaces fabricated from electropolished AISI 304 stainless steel (mirror finish, Ra ≤0.4 µm) prevent microbial adhesion and facilitate validated cleaning procedures per ISO 14644-1 Class 7 cleanroom maintenance guidelines.
• Robust refrigeration architecture: Sealed industrial-grade compressor with copper-aluminum condenser and R134a refrigerant delivers consistent cooling performance under continuous operation, even at high ambient temperatures up to +35 °C.
• Comprehensive data integrity tools: Onboard non-volatile memory logs timestamped temperature and RH values at user-defined intervals (1–60 min); data export via USB 2.0 interface supports CSV format compatibility with LIMS and ELN platforms.
• Multi-layer safety protocol: Triple-redundant thermal protection includes primary controller limit, independent mechanical over-temperature cutoff, and compressor-specific thermal overload relay—all triggering local audible alarm and visual status indicator.

Sample Compatibility & Compliance

The Labonce-500MIS accommodates standard microbiological sample formats including Petri dishes (90–150 mm), multi-well plates, slant tubes, and liquid culture flasks—up to four adjustable stainless-steel shelves (load capacity: 15 kg/shelf). Its internal dimensions (680×680×1080 mm) permit unobstructed placement of stacked incubation racks used in EPA Method 1603 (E. coli) and ISO 16266 (mold count in indoor air). The unit meets EN 61000-6-3 (EMC emission) and EN 61000-6-2 (immunity) requirements, and its optional MIT touchscreen controller provides full 21 CFR Part 11 compliance—including electronic signatures, role-based access control (administrator/operator/auditor), and immutable audit trails for all parameter changes and alarm events.

Software & Data Management

The standard LCD controller supports real-time monitoring, manual setpoint adjustment, and alarm acknowledgment. For advanced traceability, the optional MIT controller adds Ethernet connectivity, remote web-based supervision (HTTPS/TLS 1.2), and integration with enterprise-level data infrastructure via Modbus TCP or OPC UA protocols. All logged datasets include metadata: instrument ID, operator ID (if authenticated), UTC timestamps, sensor calibration IDs, and environmental deviation flags—enabling automated report generation compliant with ISO/IEC 17025 clause 7.7 (result reporting) and FDA guidance on electronic records.

Applications

• Biochemical Oxygen Demand (BOD₅) incubation per ASTM D5210 and ISO 5815-1
• Mold and yeast enumeration in water, air, and surface samples (ISO 16266, ISO 11133)
• Pharmaceutical environmental monitoring (EU Annex 1, sterile manufacturing support)
• Antifungal susceptibility testing (CLSI M38-A2)
• Food spoilage organism propagation for challenge studies (ISO 21527-1)
• Validation of disinfection efficacy against Aspergillus niger spores (EN 13697)

FAQ

What is the maximum permissible ambient temperature for continuous operation?
The Labonce-500MIS is rated for uninterrupted use at ambient temperatures between +5 °C and +35 °C, provided minimum clearance (100 mm rear, 50 mm sides) is maintained for heat dissipation.
Does the unit support validation documentation packages (IQ/OQ/PQ)?
Yes—factory-provided validation templates (including sensor calibration certificates, installation checklist, and operational test protocols) are available upon request and align with ISO/IEC 17025 and GAMP 5 principles.
Can humidity be maintained independently of temperature?
No—the humidity control system is interlocked with temperature regulation to ensure thermodynamic stability; RH setpoints are only active within the defined 15–50 °C operating envelope.
Is UV sterilization integrated into routine operation cycles?
A built-in germicidal UV-C lamp (254 nm) is standard; it operates only when the chamber is unoccupied and door interlock is engaged, with programmable exposure duration (1–60 min) and automatic lamp life monitoring.
What is the warranty coverage and service response time?
Labonce provides 24-month parts-and-labor warranty; technical support is available via email and remote diagnostics; on-site service response is guaranteed within 5 business days in major metropolitan areas across North America and EU member states.