Masterflex L/S Digital Variable-Speed Peristaltic Pump Model 07523-80
| Brand | Cole-Parmer |
|---|---|
| Origin | USA |
| Manufacturer Type | Authorized Distributor |
| Product Category | Imported Laboratory Equipment |
| Model Numbers | 07523-80, 77921-60, 77921-70, 77921-80, 77918-20, 77919-20, 77919-30 |
| Flow Range | 0.001–3400 mL/min |
| Speed Range | 0.1–600 rpm |
| Speed Accuracy | ±0.1% |
| Speed Resolution | 0.1 rpm (at 600 rpm), 0.01 rpm (at 100 rpm) |
| Motor | Brushless DC, Reversible, 1/10 HP (75 W) |
| Input Voltage | 90–260 VAC, 1.1 A @ 230 V |
| Display | Graphical LCD with multilingual interface (7 languages, including Chinese) |
| Control Modes | Continuous Run, Timed Dispense, Repeat Dispense, Volume-Based Dispense |
| Calibration | Stored per tubing size |
| Remote I/O | 0–20 mA, 4–20 mA, 0–10 V analog signals |
| Enclosure Rating | IP33 |
| Certifications | ETL, CE, ISO 9001:2000 |
| Dimensions (W×D×H) | 25.4 × 21.6 × 21.6 cm |
| Max Tubing Compatibility | Dual pump heads (07523-80) |
| Tubing Options | L/S series (e.g., Tygon LFL, Sta-Pure 500, Platinum-Cured Silicone), inner diameters 0.8–9.6 mm, wall thicknesses 1.6–2.4 mm |
| Max Pressure (High-Pressure Head) | 10.2 bar |
Overview
The Masterflex® L/S Digital Variable-Speed Peristaltic Pump Model 07523-80 is a precision-engineered laboratory-grade peristaltic pump system designed for repeatable, contamination-free fluid handling across research, bioprocessing, analytical chemistry, and quality control environments. Based on the proven Couette-type peristaltic principle—where rollers compress flexible tubing against a rigid housing to generate positive displacement—the 07523-80 delivers high-fidelity flow control without fluid contact with mechanical components. Its brushless DC motor ensures long-term stability, zero maintenance, and precise speed regulation down to 0.1 rpm with ±0.1% accuracy across its full 0.1–600 rpm range. The pump’s architecture supports both single- and dual-head configurations, enabling scalable throughput from microliter-per-minute dispensing to 3.4 L/min aggregate flow using high-pressure L/S tubing (e.g., #36, 9.6 mm ID). Designed for integration into automated workflows, it accepts analog (0–10 V, 4–20 mA) and digital remote commands for start/stop, direction reversal, and speed modulation—making it suitable for GLP-compliant process validation and FDA 21 CFR Part 11–enabled systems when paired with compliant software.
Key Features
- Dual-head expandability: Driver 07523-80 accommodates two L/S pump heads simultaneously; model 07523-90 supports up to four heads for parallel or sequential multi-channel operation.
- Graphical LCD interface with seven-language support—including fully localized Chinese menus—for intuitive setup of flow rate, volume dispense, timing intervals (up to 99 h 59 min 59 s), and cycle count (1–9999).
- Four programmable operating modes: Continuous Run, Timed Dispense, Repeat Dispense (with inter-cycle delay), and Volume-Based Dispense—enabling precise filling of vials, microplates, or reactors.
- Onboard calibration memory stores optimized flow coefficients for all standard L/S tubing sizes (e.g., #13 through #36), allowing users to apply fluid-specific correction factors based on viscosity and density—critical for accurate low-volume (<1 mL) delivery.
- Anti-drip functionality via pre- and post-pump reverse rotation ensures volumetric fidelity during stop/start transitions and eliminates residual dripping in gravity-fed lines.
- IP33-rated enclosure provides protection against vertically falling water droplets and solid objects >2.5 mm—suitable for benchtop use in controlled laboratory environments.
- Comprehensive tubing compatibility: Supports Easy-Load™ III, Easy-Load II, high-pressure, PTFE-lined, and sterile biopharmaceutical-grade pump heads (e.g., platinum-cured silicone, Sta-Pure® 500) for applications ranging from aggressive solvents to cell culture media.
Sample Compatibility & Compliance
The 07523-80 is compatible with a broad spectrum of chemically resistant, USP Class VI–certified tubing materials—including Tygon® LFL (low extractables), Sta-Pure 500 (fluoroelastomer-lined for strong acids/bases), and platinum-cured silicone (for USP / cytotoxicity testing). Its design conforms to ISO 9001:2000 quality management requirements and carries ETL and CE marks for electrical safety and electromagnetic compatibility (EMC). When operated with validated tubing sets and documented calibration procedures, the system meets critical regulatory expectations for traceability and reproducibility in pharmaceutical manufacturing (ICH Q5, Q7), clinical diagnostics (CLIA), and environmental testing (EPA Method 1664). Audit-ready data logging—when integrated with third-party SCADA or LIMS platforms—supports 21 CFR Part 11 electronic record integrity through time-stamped event logs and user-access controls.
Software & Data Management
While the 07523-80 operates autonomously via its front-panel interface, its analog and digital I/O ports enable seamless integration with external control systems. Standard 0–10 V and 4–20 mA inputs allow real-time speed modulation from PLCs or DAQ systems; discrete TTL-level signals support remote start/stop and direction toggling. For advanced data capture, optional Masterflex FlowVision® software (sold separately) provides PC-based configuration, real-time flow monitoring, batch reporting, and CSV export of dispense logs—including timestamps, target vs. actual volume, and motor load metrics. All calibration parameters are retained in non-volatile memory—even after power loss—ensuring continuity across shifts and reducing requalification effort in GMP settings.
Applications
- Automated liquid handling in analytical labs: HPLC mobile phase delivery, titrant dosing, and sample dilution.
- Biomanufacturing: Media and buffer transfer, harvest clarification, and perfusion bioreactor feed control.
- Pharmaceutical QC: Sterile filling of vials, syringes, and cartridges using validated platinum-cured silicone tubing.
- Environmental testing: Continuous sampling of wastewater streams with corrosion-resistant Sta-Pure 500 tubing.
- Academic research: Precise reagent addition in kinetic assays, microfluidic priming, and gradient generation.
- Food & beverage R&D: Flavor dosing, viscosity-dependent pumping of sauces and emulsions using thick-walled #15–#35 tubing.
FAQ
What tubing sizes are supported by the 07523-80 driver?
The driver is compatible with all L/S-series tubing—from #13 (0.8 mm ID) to #36 (9.6 mm ID)—when used with appropriate pump heads (e.g., Easy-Load III for smaller IDs; high-pressure head for #35/#36).
Can this pump be used in GMP environments?
Yes—provided tubing is qualified, calibration is documented per SOP, and electronic records are managed under a 21 CFR Part 11–compliant platform. The driver’s stable speed control and audit-trail-capable I/O support such validation.
How does flow calibration account for fluid properties?
Each tubing size has a stored baseline flow coefficient. Users can apply a secondary correction factor derived from gravimetric or volumetric measurement of their specific fluid—compensating for viscosity, density, and tubing elasticity effects.
Is remote programming of dispense parameters possible?
Yes—via analog voltage/current signals or digital TTL inputs. Full parameter upload (target volume, cycles, interval) requires integration with Masterflex FlowVision® or custom LabVIEW/Python scripts using Modbus RTU over RS-485 (with optional adapter).
What is the maximum backpressure tolerance?
Standard L/S pump heads operate reliably up to ~2 bar; the optional high-pressure head sustains continuous operation at up to 10.2 bar—ideal for pumping through filters, long tubing runs, or pressurized reactors.
