Hettich 7116R Benchtop High-Speed Micro-Ultracentrifuge with Refrigeration
| Key | Brand: Hettich |
|---|---|
| Origin | Hunan, China |
| Manufacturer Type | Authorized Distributor |
| Country of Origin | China |
| Model | 7116R |
| Instrument Type | Benchtop Centrifuge |
| Speed Range | 200–16,500 rpm |
| Max RCF | 22,500 × g |
| Max Capacity | 48 × 2.0 mL tubes |
| Temperature Range | −20 °C to +40 °C |
| Display | 7-inch capacitive touchscreen |
| Dimensions (W×D×H) | 650 × 350 × 325 mm |
| Rotor Configuration | Fixed-angle rotor standard (compatible with PCR 8-tube strips, 0.2–2.0 mL microtubes) |
Overview
The Hettich 7116R is a compact, refrigerated benchtop high-speed centrifuge engineered for precision micro-volume sample processing in molecular biology, clinical diagnostics, and cell biology laboratories. It operates on the principle of sedimentation under controlled rotational acceleration—utilizing fixed-angle rotor geometry to generate high relative centrifugal force (RCF) for rapid pelleting of subcellular particles, nucleic acids, proteins, and viral particles. Designed specifically for workflows requiring temperature-sensitive separation—including DNA/RNA isolation, protein precipitation, bacterial lysis supernatant clarification, and extracellular vesicle enrichment—the 7116R maintains thermal stability from −20 °C to +40 °C during operation, minimizing sample degradation during extended runs. Its footprint (650 × 350 × 325 mm) and integrated cooling system make it suitable for space-constrained biosafety cabinets, clean benches, or shared core facility environments without compromising performance integrity.
Key Features
- Compact benchtop architecture optimized for high-density lab layouts—among the smallest high-speed refrigerated centrifuges available for microtube applications.
- 7-inch full-color capacitive touchscreen interface with intuitive icon-driven navigation, real-time parameter monitoring, and multi-user profile support.
- Refrigerated operation with independent compressor-based cooling system ensuring stable temperature control across the full speed range (200–16,500 rpm).
- Fixed-angle rotor configuration supporting up to 48 × 2.0 mL microcentrifuge tubes or PCR 8-tube strips—designed for uniform sedimentation kinetics and minimal tube deformation at high RCF.
- Seven-color ambient LED lighting system providing visual status feedback (e.g., run progress, temperature alert, door interlock state) while reducing ambient glare during low-light procedures.
- Brushless frequency-controlled motor delivering high torque at low noise levels (<62 dB(A) at maximum speed), engineered for long-term operational reliability and minimal mechanical drift.
- Automatic rotor recognition and speed/temperature safety interlocks compliant with IEC 61010-2-020 requirements for laboratory centrifuges.
Sample Compatibility & Compliance
The 7116R accommodates standard polypropylene and polycarbonate microtubes (0.2–2.0 mL), including skirted and non-skirted PCR strips, low-binding tubes, and filter-based spin columns used in nucleic acid purification kits. It supports common biological matrices such as whole blood lysates, bacterial culture supernatants, tissue homogenates, and clarified cell lysates. All rotor assemblies are validated per ISO 15195:2019 for calibration traceability, and the instrument’s temperature control system meets ASTM E2500-13 criteria for verification of thermal performance in regulated environments. While not certified for GMP manufacturing, its audit trail-capable software mode (via optional firmware upgrade) supports GLP-compliant documentation requirements, including user login logging, method versioning, and run timestamping aligned with FDA 21 CFR Part 11 principles.
Software & Data Management
The embedded operating system enables storage of up to 100 customizable protocols, each with programmable ramp/deceleration profiles, hold times, and temperature setpoints. Run data—including actual speed, RCF, temperature history, elapsed time, and error codes—is logged automatically and exportable via USB flash drive in CSV format. Optional Ethernet connectivity (with firmware v2.3+) allows integration into LIMS environments through standard TCP/IP commands, supporting remote monitoring and centralized log aggregation. Audit-ready reporting includes operator ID, date/time stamps, rotor serial number, and deviation alerts—facilitating internal quality reviews and regulatory readiness assessments.
Applications
- Nucleic acid purification: Rapid pelleting of silica-membrane-bound DNA/RNA from binding buffers; efficient removal of ethanol carryover in wash steps.
- Protein biochemistry: Precipitation of recombinant proteins using ammonium sulfate or TCA; clarification of inclusion body lysates prior to refolding.
- Virology and exosome research: Concentration of lentiviral vectors and extracellular vesicles from conditioned media at ≥20,000 × g.
- Clinical microbiology: Separation of white blood cell layers from whole blood (buffy coat isolation); preparation of serum/plasma fractions for immunoassays.
- Environmental and food testing: Recovery of microbial cells from water or food extract matrices prior to qPCR or sequencing library prep.
FAQ
What is the minimum detectable speed increment?
The speed resolution is 10 rpm across the full range (200–16,500 rpm).
Does the 7116R support swing-bucket rotors?
No—this model is configured exclusively for fixed-angle rotors optimized for microtube applications.
Is rotor balancing required before every run?
Yes. The unit enforces symmetrical loading per manufacturer guidelines; imbalance detection triggers automatic shutdown if deviation exceeds ±0.5 g.
Can the centrifuge be operated without refrigeration?
Yes—temperature can be set to “ambient” mode, disabling compressor activation while retaining all other operational functions.
What is the warranty coverage period?
Standard warranty is 24 months parts and labor, extendable to 36 months with annual service contract enrollment.
