CK MPA2 Multi-Probe Skin Assessment System
| Brand | CK |
|---|---|
| Origin | Germany |
| Manufacturer Status | Authorized Distributor |
| Origin Category | Imported |
| Model | MPA2 |
| Pricing | Upon Request |
Overview
The CK MPA2 Multi-Probe Skin Assessment System is a modular, handheld platform engineered for objective, non-invasive biophysical evaluation of skin surface properties in clinical dermatology, cosmetic R&D, and regulatory-compliant efficacy studies. Built upon CK’s legacy of precision instrumentation since 1980, the MPA2 operates as a centralized data acquisition hub that interfaces with up to eight interchangeable, calibrated probes—each designed to measure a distinct biophysical parameter according to standardized measurement principles (e.g., capacitance for stratum corneum hydration, open-chamber evaporimetry for transepidermal water loss, diffuse reflectance spectroscopy for melanin/erythema index, thermistor-based contact sensing for surface temperature). Its portable architecture enables consistent measurements across diverse settings—including clinical trial sites, formulation labs, and in vivo test centers—while maintaining traceability to CK’s DIN EN ISO/IEC 17025-accredited calibration protocols.
Key Features
- Modular probe architecture supporting simultaneous or sequential attachment of up to eight validated CK probes without recalibration
- Integrated touchscreen interface with real-time parameter visualization, on-device data logging, and USB-C export capability
- Automatic probe recognition and firmware synchronization via CK’s proprietary communication protocol
- Battery-powered operation (up to 8 hours continuous use) with low-power standby mode for field deployment
- Robust aluminum-magnesium alloy housing rated IP54 for dust and splash resistance in laboratory and clinical environments
- Compliance with IEC 61000-4 electromagnetic compatibility standards and medical device safety requirements per IEC 60601-1 (Class II, Type BF applied part)
Sample Compatibility & Compliance
The MPA2 system is validated for use on human volar forearm, cheek, forehead, and dorsal hand—sites commonly specified in ISO 16128, COLIPA (now Cosmetics Europe), and OECD Test Guideline 439 protocols. All connected probes adhere to CK’s internal validation criteria aligned with ASTM E2853 (for colorimetric reproducibility), ISO 24444 (for TEWL measurement uncertainty), and ISO 24442 (for corneometry). The system supports Good Clinical Practice (GCP) and Good Laboratory Practice (GLP) workflows through audit-trail-enabled software (via optional CK USB Link module), enabling full traceability of operator ID, timestamp, probe serial number, calibration status, and raw sensor output—critical for submissions to FDA, EMA, and Health Canada.
Software & Data Management
Data acquisition and analysis are managed via CK’s proprietary MPA Control Software v4.2, compatible with Windows 10/11. The software provides synchronized multi-parameter time-series plots, statistical reporting (mean ± SD, CV%, % change vs baseline), and automated export to CSV, PDF, or XML formats compliant with CDISC SDTM standards. When paired with CK’s optional USB Link Module, the system supports 21 CFR Part 11–compliant electronic signatures, role-based user access control, and immutable audit trails—including record creation/modification timestamps, operator authentication logs, and calibration certificate linkage. Raw sensor data is stored with embedded metadata (probe type, firmware version, ambient conditions), ensuring full analytical traceability from acquisition to final report.
Applications
- Evaluation of moisturizer efficacy through concurrent measurement of SC hydration (Corneometer CM825), TEWL (Tewameter TM Hex), and skin surface temperature (Skin-Thermometer ST500)
- Objective quantification of anti-pigmentation actives using Mexameter MX18 (melanin index) and Colorimeter CL400 (L*a*b* coordinates)
- Barrier function assessment via combined TEWL, pH (Skin-pH-Meter PH905), and friction coefficient (Frictiometer FR700) profiling
- In vivo photoprotection testing by monitoring erythema development (MX18 hemoglobin index) pre- and post-UV exposure
- Clinical endpoint support for cosmetic claims substantiation under EU Regulation (EC) No 1223/2009 Annex I requirements
- Longitudinal monitoring in chronic dermatoses (e.g., atopic dermatitis, psoriasis) using composite indices derived from ≥4 parameters
FAQ
Is the MPA2 platform compatible with third-party probes?
No. The MPA2 communicates exclusively with CK-manufactured, firmware-signed probes to ensure metrological integrity and compliance with CK’s calibration chain.
What is the recommended calibration interval for the MPA2 system?
CK recommends annual calibration against NIST-traceable reference standards; probe-specific intervals are defined in each probe’s Certificate of Conformance (e.g., Corneometer CM825: 12 months, Mexameter MX18: 18 months).
Can the MPA2 be used in regulated clinical trials?
Yes—when deployed with CK USB Link Module and MPA Control Software v4.2, it meets ALCOA+ data integrity principles and supports 21 CFR Part 11 and Annex 11 compliance requirements.
Does the system require external power during operation?
No. The integrated rechargeable Li-ion battery supports full functionality for ≥8 hours; AC adapter is provided only for charging and firmware updates.
How is ambient condition data integrated into measurements?
The Ambient Condition Sensor (ACS) continuously logs temperature and relative humidity; this metadata is automatically time-stamped and appended to all concurrent probe datasets to support environmental correction algorithms in post-processing.
