Liebherr SRFvh 5511 Laboratory Refrigerator

Overview

The Liebherr SRFvh 5511 is a high-precision, DIN 13277-compliant laboratory refrigerator engineered for the secure, stable, and traceable storage of temperature-sensitive biological materials, pharmaceuticals, vaccines, reference standards, and clinical samples. Unlike general-purpose refrigeration units, this model employs a forced-air cooling system with microprocessor-controlled circulation and dual-sensor feedback to maintain temperature uniformity across the entire storage volume. Its operational range of +3 °C to +16 °C is specifically calibrated for applications requiring avoidance of freezing while preserving enzymatic activity, antigen integrity, and chemical stability—critical for GxP-regulated environments including GLP, GMP, and ISO/IEC 17025-accredited laboratories. The unit’s ±2.0 °C temperature stability (as verified per DIN 13277 Annex B) ensures that deviations from setpoint remain within internationally accepted limits for pharmaceutical cold chain continuity, supporting compliance with WHO guidelines for vaccine storage and USP on storage and handling of pharmaceuticals.

Key Features

• DIN 13277 Certification: Fully validated against the German national standard for laboratory and medicinal refrigerators, covering thermal performance, alarm functionality, recovery time, and insulation integrity.
• +2 °C Safety Device: An independent thermal safeguard that triggers audible/visual alarms and initiates corrective action if internal temperature drops below +2 °C—preventing accidental freezing of biologics or reagents without manual intervention.
• Forced-Air Circulation & Automatic Defrost: Ensures homogeneous temperature distribution (≤3.3 °C gradient, ≤2.0 °C fluctuation) and eliminates manual maintenance downtime associated with manual defrost cycles.
• Integrated Connectivity: Built-in Wi-Fi and Ethernet interfaces enable seamless integration with Liebherr SmartMonitoring software for remote real-time monitoring, event logging, and audit-ready data export—supporting FDA 21 CFR Part 11 requirements for electronic records and signatures when paired with appropriate validation protocols.
• Robust Physical Security: Mechanical lock with two physical keys prevents unauthorized access; tamper-evident design aligns with ISO 22320 and laboratory security SOPs for controlled substances and regulated samples.
• Energy-Efficient Architecture: Optimized compressor operation, low-GWP refrigerant (R600a), high-efficiency LED lighting, and vacuum-insulated panels reduce annual energy consumption to 360 kWh—meeting EU Energy Label Class F criteria under EN 62552-3.

Sample Compatibility & Compliance

The SRFvh 5511 accommodates a broad spectrum of sample formats—including vials, cryotubes, multiwell plates, serum bottles, and primary packaging—within its 440 L net usable volume. Five fully adjustable, plastic-coated wire shelves (600 × 536 mm, 60 kg capacity each) allow flexible configuration for stacked or staggered loading. The tempered glass door provides visual inventory verification without thermal disruption, while the vertical LED lighting system minimizes UV exposure and heat generation. All materials in contact with stored items comply with USP Class VI biocompatibility testing. The unit meets DIN 13277 requirements for alarm response time (2 K), recovery time (<30 min after 3-min door opening), and thermal mapping validation readiness. It is suitable for use in facilities undergoing MHRA, EMA, or FDA inspections where documented temperature control and deviation management are mandatory.

Software & Data Management

Liebherr SmartMonitoring software provides centralized, role-based access to real-time temperature streams, historical trend analysis, and configurable alarm thresholds. Data is timestamped, encrypted, and stored locally on-device with optional cloud synchronization. USB export supports CSV-formatted logs compatible with LIMS, ELN, and QMS platforms. Audit trails record all user actions—including setpoint changes, alarm acknowledgments, and door-open events—with immutable timestamps. When deployed with IQ/OQ documentation packages, the system satisfies ALCOA+ principles (Attributable, Legible, Contemporaneous, Original, Accurate, Complete, Consistent, Enduring, Available) required for regulatory submissions and internal quality audits.

Applications

• Long-term storage of monoclonal antibodies, recombinant proteins, and diagnostic reagents at +4 °C–+8 °C
• Vaccine stabilization prior to distribution (aligned with WHO PQS specifications)
• Controlled environment for QC sample retention per ICH Q5C and pharmacopoeial monographs
• Reference standard storage under ISO Guide 34 and ISO/IEC 17034 requirements
• Biobank specimen staging before cryopreservation or downstream assay processing
• Stability chamber pre-conditioning support for accelerated degradation studies (ICH Q1A)

FAQ

Does the SRFvh 5511 meet FDA 21 CFR Part 11 requirements?
Yes—when operated with Liebherr SmartMonitoring configured with electronic signatures, audit trail logging, and user access controls, it supports compliance with Part 11 for electronic records and signatures.
What is the maximum ambient temperature for reliable operation?
The unit is rated for continuous operation in ambient conditions between +10 °C and +35 °C, as validated per DIN 13277 Section 6.2.
Can temperature data be exported for regulatory review?
Yes—via USB interface, users can export full-resolution, time-stamped temperature logs in CSV format, including alarm events and system status flags.
Is the +2 °C Safety Device independent of the main controller?
Yes—it utilizes a dedicated thermistor and circuitry separate from the primary control system to ensure fail-safe protection against freezing.
How many shelves are included, and are they load-rated?
Five adjustable wire shelves are supplied, each rated for 60 kg uniformly distributed load; total unit static load capacity is 300 kg.