Hanuo HDKT200-1 Single-Module Dry Block Heater

Overview

The Hanuo HDKT200-1 Single-Module Dry Block Heater is a precision-engineered thermal platform designed for consistent, contact-based heating of samples in tubes, vials, and microplates without the operational constraints of water baths. Utilizing resistive heating film technology embedded beneath a solid aluminum heating block, it delivers rapid thermal response and high spatial uniformity across the sample interface—critical for applications requiring strict thermal reproducibility and contamination-free operation. Unlike liquid baths, this dry block system eliminates evaporation, condensation, microbial growth, and cross-contamination risks, making it suitable for molecular biology workflows, clinical diagnostics, and regulated quality control environments where traceability and cleanliness are mandated.

Key Features

• Microprocessor-controlled PID temperature regulation with real-time digital display (0.1 °C resolution) and countdown timer
• Dual independent parameter setting: simultaneous configuration of target temperature and hold time
• Five-stage programmable temperature profile (ramp-soak sequences) for complex thermal protocols
• Integrated temperature calibration offset function for traceable accuracy adjustment per lab SOP
• Modular interchange system enabling rapid swap of standardized aluminum blocks (6–40 mm tube diameters; 0.2–2.0 mL formats; 96-well PCR plates; custom configurations available)
• Over-temperature safety cutoff with visual indicator and audible alarm; certified 250 V / 3 A fast-blow fuse
• Low-noise, energy-efficient operation (200 W nominal) with thermal stability ≤ ±0.5 °C over full range and ≤0.3 °C uniformity at 40 °C
• Tactile membrane keypad and backlit LCD interface for gloved-hand usability in biosafety cabinets or cleanrooms

Sample Compatibility & Compliance

The HDKT200-1 supports a broad range of standard laboratory consumables via interchangeable, anodized aluminum modules—including round-bottom and conical tubes (6–40 mm OD), PCR strip tubes, 0.2 mL and 0.5 mL microcentrifuge tubes, 1.5/2.0 mL Eppendorf-style tubes, and flat-bottom 96-well microtiter plates. All modules undergo surface passivation to resist corrosion from common reagents (e.g., ethanol, isopropanol, dilute acids/bases) and withstand repeated autoclaving (121 °C, 20 min) or chemical disinfection (70% IPA, sodium hypochlorite). The device complies with IEC 61010-1:2010 for electrical safety in laboratory equipment and meets EMC requirements per EN 61326-1:2013. While not FDA-cleared as a medical device, its design supports GLP/GMP-aligned documentation practices—including audit-ready temperature logging when paired with optional RS232/USB data export.

Software & Data Management

Standalone operation requires no external software; all parameters are configured directly via front-panel controls. For integration into automated lab environments, the HDKT200-1 offers optional serial communication (RS232) or USB-to-serial interfaces supporting ASCII command protocols. This enables bidirectional data exchange—including real-time temperature streaming, setpoint updates, alarm status polling, and event-triggered data capture—for inclusion in LIMS or ELN systems. When used with compliant third-party software, the unit supports electronic record integrity per FDA 21 CFR Part 11 (with user authentication, audit trail, and electronic signature capability), provided the host application implements required security controls.

Applications

• DNA denaturation and pre-PCR heat activation (e.g., Taq polymerase activation at 95 °C)
• Enzyme inactivation (e.g., restriction digest termination at 65–80 °C)
• Serum coagulation assays (37 °C incubation with precise endpoint timing)
• Cell lysis buffer pre-warming prior to RNA/DNA extraction
• Standard curve preparation in ELISA and immunoassays requiring consistent plate heating
• Calibration verification of thermocouples and RTDs using NIST-traceable reference blocks
• Stability testing of pharmaceutical formulations under accelerated thermal conditions (per ICH Q1A)

FAQ

What is the maximum operating temperature, and is it validated across the entire block surface?
The HDKT200-1 achieves a maximum setpoint of 150 °C. Temperature uniformity is specified as ≤ ±0.5 °C across the active zone, verified per ASTM E220-19 methodology using calibrated PT100 probes at nine spatial points.
Can the unit be used for overnight incubations?
Yes—time settings support durations up to 99 hours and 59 minutes, with automatic shutdown upon completion. Thermal drift remains within specification over extended periods when ambient conditions are stable (20–25 °C, <60% RH).
Is module calibration traceable to national standards?
The instrument includes a user-accessible temperature offset function. Final calibration should be performed using a NIST-traceable reference thermometer (e.g., Fluke 1523/1524) against a certified thermocouple or RTD probe inserted into designated calibration wells in the block.
Does the device meet ISO/IEC 17025 requirements for accredited testing labs?
While the HDKT200-1 itself is not ISO/IEC 17025-certified, its metrological characteristics (accuracy, uniformity, stability) and programmable audit features enable laboratories to establish and validate their own uncertainty budgets and calibration procedures in accordance with Clause 6.4 and Annex A.3 of ISO/IEC 17025:2017.
Are replacement modules available for non-standard tube sizes?
Yes—Hanuo provides OEM manufacturing services for custom-machined aluminum blocks. Customers may supply dimensional drawings and material specifications (e.g., 6061-T6 aluminum, anodized finish) for quotation and lead-time confirmation.