HUXI HPN-16 Vacuum Parallel Concentrator

Overview

The HUXI HPN-16 Vacuum Parallel Concentrator is an engineered solution for high-throughput, reproducible solvent removal from multiple liquid samples under controlled low-pressure and regulated thermal conditions. Based on the principle of vacuum-assisted centrifugal evaporation, the system simultaneously applies gentle rotational motion, precise water-bath heating, and programmable vacuum reduction to accelerate solvent volatilization while minimizing sample degradation, oxidation, or cross-contamination. Unlike conventional rotary evaporators—each requiring individual setup and monitoring—the HPN-16 standardizes evaporation kinetics across all 16 positions via synchronized control of temperature, vacuum, rotation, and lid heating. This ensures uniform concentration endpoints and eliminates inter-sample variability caused by inconsistent ambient exposure or manual intervention. Designed for laboratories performing routine batch processing in analytical chemistry, environmental testing, pharmaceutical QC, and clinical research, the HPN-16 supports GLP-aligned workflows through audit-ready parameter logging and repeatable process execution.

Key Features

• Four-sided transparent borosilicate glass chamber enabling real-time visual monitoring of all 16 samples without interrupting operation;
• Vacuum-tight heated lid with independent temperature control (≥80 °C), preventing condensate re-entry and enhancing solvent capture efficiency;
• Dedicated anti-backflow grooves integrated into the lid sealing interface, eliminating cross-contamination between adjacent vials during simultaneous evaporation;
• Top-hinged, lift-up lid design allowing rapid access to all positions—no disassembly or relocation required before or after runs;
• Modular control architecture: independent on/off switching for lighting, rotation, auto-drain, and pressure release functions to accommodate multi-step protocols;
• Multi-parameter programmability with up to 8-stage gradients for water bath temperature, lid temperature, vacuum setpoint, and rotational speed—enabling method optimization for thermolabile analytes such as pesticides, metabolites, or oligonucleotides;
• Capacitive color touchscreen interface with intuitive navigation, real-time parameter visualization, and event-based alarm notifications (e.g., vacuum loss, temperature deviation, drain full);
• Integrated automatic condensate drainage system with level sensing, eliminating manual emptying and supporting unattended operation for >8 hours.

Sample Compatibility & Compliance

The HPN-16 accommodates standard 200 mL round-bottom or flat-bottom collection vials (including those conforming to ASTM D5297 and ISO 11843-3 specifications for volumetric recovery). Its sealed evaporation environment meets requirements for handling volatile organic compounds (VOCs) in accordance with EPA Method 502.2 and EN ISO 15681-2. The instrument’s closed-loop vacuum and condensation management support compliance with laboratory safety standards including OSHA 29 CFR 1910.1200 (Hazard Communication) and EU Directive 2004/37/EC (Carcinogens and Mutagens). While not certified for GMP production environments, its programmable parameters, timestamped operation logs, and non-volatile memory make it suitable for FDA 21 CFR Part 11–aligned data integrity practices when paired with validated SOPs and electronic lab notebook (ELN) integration.

Software & Data Management

The HPN-16 operates via embedded firmware with no external PC dependency. All user-defined methods—including temperature ramps, vacuum profiles, and rotation sequences—are stored locally in non-volatile memory with time/date stamping. The system records operational events (start/stop times, vacuum fluctuations, temperature deviations >±1 °C, drain cycles) for traceability. Export functionality is limited to USB-triggered CSV log dumps for post-run analysis in third-party statistical packages (e.g., JMP, Minitab). No cloud connectivity or remote access is implemented, preserving data sovereignty—a critical consideration for regulated labs handling proprietary or sensitive biological matrices.

Applications

• Residue Analysis: Parallel concentration of QuEChERS extracts from fruits, vegetables, cereals, and plant tissues prior to GC-MS or LC-MS/MS detection;
• Environmental Monitoring: Pre-concentration of aqueous samples (drinking water, groundwater, wastewater effluents) for trace metal or organic contaminant quantification per ISO 17294-2 and EPA 1631E;
• Food & Beverage Quality Control: Solvent removal from dairy, beer, wine, and juice matrices prior to sensory or stability testing;
• Clinical & Biomedical Research: Gentle volume reduction of serum, plasma, urine, and CSF samples without denaturing proteins or degrading small-molecule biomarkers;
• Pharmaceutical Development: Batch-wise concentration of herbal extracts, active pharmaceutical ingredient (API) solutions, and stability study samples under ICH Q5C-compliant thermal conditions.

FAQ

What types of solvents are compatible with the HPN-16?
The system is validated for use with common low-boiling-point solvents including methanol, ethanol, acetonitrile, ethyl acetate, dichloromethane, and hexane. High-boiling solvents (e.g., DMSO, glycerol) require extended run times and are not recommended for fixed-volume endpoint modes.
Can the HPN-16 achieve nitrogen purging?
No—this model lacks integrated gas inlet ports. It relies solely on vacuum-based solvent removal; inert gas sparging must be performed externally prior to loading.
Is calibration documentation provided with the unit?
Factory calibration certificates for temperature sensors (water bath and lid) and vacuum transducer are included. Users are responsible for periodic verification per internal QA procedures or ISO/IEC 17025 requirements.
Does the HPN-16 support remote monitoring or network connectivity?
No—this is a standalone instrument with local-only control and data storage. Ethernet or Wi-Fi interfaces are not available.
What maintenance intervals are recommended?
Vacuum pump oil should be changed every 500 operating hours; O-rings and gaskets require inspection every 6 months or after 200 cycles. Full service is advised annually by authorized HUXI technical personnel.