Analytik Jena Cybi-FeliX Automated Liquid Handling Workstation
| Brand | Analytik Jena |
|---|---|
| Origin | Germany |
| Manufacturer | Analytik Jena AG |
| Product Type | Imported |
| Model | Cybi-FeliX |
| Pricing | Upon Request |
Overview
The Analytik Jena Cybi-FeliX Automated Liquid Handling Workstation is a benchtop-integrated platform engineered for precision, flexibility, and reproducibility in routine and high-throughput liquid handling tasks. Based on the proprietary CHOICE™ technology, it implements a single-channel, variable-volume air-displacement pipetting principle—enabling continuous volume adjustment across an unprecedented 0.5–1000 µL range without physical tip or head exchange. This architecture eliminates mechanical reconfiguration delays while maintaining traceable, ISO/IEC 17025-aligned volumetric performance. Designed for compliance-critical environments—including GLP, GMP, and clinical research labs—the system integrates seamlessly into workflows requiring assay setup, serial dilution, plate replication, reagent dispensing, and sample normalization. Its compact footprint (650 × 450 mm) supports deployment in space-constrained biosafety cabinets or shared core facilities without compromising functional capacity.
Key Features
- CHOICE™ Pipetting Head: A single, motorized, electronically controlled pipetting head delivering 0.5–1000 µL with calibrated accuracy per ISO 8655-2: ≤2% CV at 3–5 µL; ≤1% CV at 100–1000 µL.
- Modular Tip Adapter System: Auto-switching liquid handling adapters enable dynamic mode selection—single-well, row-wise, column-wise, or full-plate dispensing—without manual intervention or head replacement.
- 12-Position Deck Layout: Configurable deck accommodates standard SBS-format microplates (96-well, 384-well), tube racks (1.5 mL, 2.0 mL, PCR strips), reservoirs, and custom labware via programmable coordinate mapping.
- CyBi®-TipTray Sealed Tip Technology: Patented pneumatic sealing ensures consistent tip ejection force and minimizes carryover risk; supports both low-retention and standard filter tips.
- Integrated Calibration & Diagnostics: Onboard gravimetric calibration verification (per ASTM E1153), real-time pressure monitoring, and tip detection sensors ensure operational integrity before each run.
Sample Compatibility & Compliance
The Cybi-FeliX handles aqueous buffers, viscous glycerol solutions (up to 50% v/v), serum-containing media, and low-surface-tension solvents (e.g., DMSO up to 10%). It supports ANSI/SBS-compliant plates and non-standard containers via user-defined labware definitions. The system meets essential regulatory requirements for instrument qualification: IQ/OQ documentation templates are provided, and software operation complies with FDA 21 CFR Part 11 (audit trail, electronic signature, role-based access control) when used with CyBi-Software Suite v5.2+. All mechanical components adhere to EU Machinery Directive 2006/42/EC and EMC Directive 2014/30/EU.
Software & Data Management
CyBi-Software Suite provides a graphical, drag-and-drop protocol builder with contextual validation—highlighting potential volume conflicts, tip collisions, or deck overruns in real time. Protocols support nested loops, conditional logic (e.g., “if absorbance >0.8, repeat dilution”), and integration with external devices via RS232, USB-HID, or TCP/IP. Raw data export includes timestamped CSV logs with full metadata: tip lot numbers, environmental temperature/humidity (via optional sensor module), and step-by-step execution status. Audit trails record all user actions, parameter changes, and calibration events with immutable timestamps—fully compliant with ALCOA+ principles for data integrity.
Applications
- High-content screening (HCS) assay setup for 384-well imaging plates with sub-microliter DMSO stock addition.
- qPCR master mix preparation with dual-volume dispensing: 2 µL enzyme + 18 µL buffer per well, using single-head dynamic range switching.
- Cell-based toxicity profiling: serial 1:3 dilutions across 11 points in 96-well format, including intermediate plate-to-plate transfer.
- ELISA kit reconstitution and plate coating with humidity-controlled tip storage to prevent evaporation during multi-hour runs.
- Biobanking: automated aliquoting of plasma samples into cryovials with barcode tracking and LIMS integration via HL7 or REST API.
FAQ
Does the Cybi-FeliX require dedicated compressed air or vacuum sources?
No—it operates using an integrated, oil-free diaphragm pump with adjustable pressure and vacuum setpoints (5–85 kPa), eliminating dependency on facility utilities.
Can the system be validated for regulated pharmaceutical use?
Yes. Full IQ/OQ/PQ documentation packages—including test scripts, acceptance criteria, and raw data templates—are available upon request and align with ICH Q2(R2) and USP guidelines.
Is remote monitoring supported?
Yes. The workstation connects to local networks via Ethernet; status dashboards and alarm notifications (email/SNMP) are configurable through the CyBi-Cloud Gateway module.
What maintenance intervals are recommended?
Preventive maintenance is scheduled every 12 months or 2,000 operating hours, whichever occurs first; includes pipetting axis recalibration, seal inspection, and firmware verification.
How is cross-contamination prevented during multi-sample processing?
The system executes automatic tip wiping (programmable dwell time and position), aspirate/dispense height optimization, and post-run decontamination cycles using ethanol or sodium hypochlorite-compatible protocols.
