CoMetro CP-M Series Precision Piston Pump
| Brand | CoMetro |
|---|---|
| Model | CP-M Series |
| Flow Rate | 10 mL/min (model-dependent, up to 50 mL/min) |
| Maximum Pressure | 6000 psi (413.7 bar) |
| Accuracy | ±2% |
| Precision (RSD) | 0.2% |
| Dimensions | 175(H) × 225(W) × 305(D) mm |
| Weight | 11 kg |
| Power Supply | 115/230 V, 50/60 Hz |
| Fluid Path Materials | PEEK or 316 Stainless Steel |
| Control Interface | Keypad + RS232 digital communication |
| Pressure Sensing | Non-contact electronic transducer |
| Flow Stability | Pulse-free via low-volume accumulator and electronic compensation |
Overview
The CoMetro CP-M Series Precision Piston Pump is an engineered constant-flow delivery system designed for high-pressure, high-accuracy liquid handling in analytical, synthetic, and process development laboratories. Based on positive displacement piston actuation with real-time electronic flow compensation, the CP-M series eliminates pulsation through a proprietary low-inner-volume accumulator and adaptive motor control architecture. Unlike peristaltic or diaphragm-based systems, this pump delivers true volumetric consistency under variable backpressure—critical for applications such as preparative HPLC, continuous-flow chemistry, catalyst screening, and microreactor feeding. Its robust mechanical design integrates a suspended pump head assembly, precision-machined check valves, and dynamic pressure feedback to maintain flow stability across its full operating range, even at maximum rated pressure (6000 psi / 413.7 bar).
Key Features
- Pulse-free flow delivery enabled by low-volume hydraulic accumulator and real-time electronic compensation algorithm
- Non-contact pressure transduction system providing continuous monitoring without mechanical wear or fluid pathway intrusion
- Dual-control architecture: local keypad operation and remote digital command via RS232 interface with configurable analog input (0–5 V or 0–10 V) and frequency modulation support
- Modular fluid path options: chemically resistant PEEK or USP Class VI-compliant 316 stainless steel for compatibility with aggressive solvents, acids, bases, and biological buffers
- Integrated safety logic including programmable high/low pressure limits, automatic fault detection, and visual/audible alarm triggers
- Self-cleaning bypass valve configuration minimizes residue carryover and supports routine maintenance protocols compliant with GLP and ISO 17025 laboratory practices
Sample Compatibility & Compliance
The CP-M Series accommodates a broad spectrum of liquids—from aqueous buffers and organic solvents (e.g., THF, DMF, acetonitrile) to viscous reagents (up to 500 cP) and suspensions containing particles <5 µm. All wetted materials meet USP Class VI biocompatibility standards when configured with PEEK; stainless steel variants comply with ASTM A276 and EN 10088-1 specifications. The pump’s design supports method traceability requirements under FDA 21 CFR Part 11 when operated with validated software environments. Pressure and flow data logging—when paired with CoMetro’s optional PC-based control suite—enables audit-ready records for GMP-regulated R&D workflows.
Software & Data Management
While the CP-M Series operates autonomously via front-panel controls, its RS232 port enables bidirectional communication with host systems for integration into automated platforms (e.g., robotic liquid handlers, reaction monitoring suites). Firmware supports SCPI-like command syntax for parameter setting (flow rate, pressure limits, run duration), status polling (current pressure, motor temperature, valve state), and event-driven alerts. Data output includes timestamped flow and pressure values at user-defined intervals (1–10 Hz), exportable to CSV or directly ingested by LabVIEW, MATLAB, or custom Python scripts. Audit trail functionality—including operator ID tagging and parameter change logs—is available when deployed with CoMetro’s certified control software (v3.2+), satisfying ALCOA+ data integrity principles.
Applications
- Preparative and semi-preparative liquid chromatography requiring stable gradient delivery at pressures up to 6000 psi
- Continuous-flow synthesis systems where stoichiometric precision and residence time control are essential
- Calibration and verification of flow sensors, mass flow meters, and inline spectrophotometers
- Cell culture media perfusion and microfluidic device priming under sterile conditions (PEEK-configured units)
- High-pressure material testing rigs, including corrosion studies and catalyst durability evaluation
- Undergraduate and graduate teaching labs focused on fluid mechanics, process instrumentation, and analytical method validation
FAQ
What is the minimum programmable flow rate for the CP-M205 model?
The CP-M205 supports flow rates from 0.001 mL/min, making it suitable for nanoliter-scale dosing in microreactor and assay development applications.
Can the CP-M Series be integrated into a PLC-controlled environment?
Yes—via analog voltage/frequency input and RS232 serial protocol, the pump accepts external setpoints and reports operational status to industrial controllers compliant with Modbus RTU or custom ASCII framing.
Is pressure calibration traceable to NIST standards?
Factory calibration uses NIST-traceable deadweight testers; field recalibration kits and certificate documentation are available upon request for ISO/IEC 17025-accredited labs.
How does the self-cleaning bypass function during extended idle periods?
The integrated bypass valve cycles automatically every 24 hours (configurable) to purge stagnant fluid and prevent crystallization or biofilm formation in the check valve seats.
Are firmware updates provided post-purchase?
Yes—CoMetro releases validated firmware revisions annually, with version history, release notes, and installation guides accessible through registered customer portals.

