CoMetro CP-M305 High-Pressure Constant Flow Pump for Fixed-Bed Reactor Systems
| Brand | CoMetro |
|---|---|
| Model | CP-M305 |
| Flow Rate | 0.001–5 mL/min |
| Maximum Pressure | 60,000 psi |
| Construction Material | Stainless Steel or PEEK (user-selectable) |
| Display & Control | Real-time flow rate, pressure, pressure upper/lower limits, operational status, and alarm indicators |
| Compliance | Designed for GLP/GMP-aligned lab environments |
Overview
The CoMetro CP-M305 is a high-precision, micro-volume constant flow pump engineered for demanding catalytic reaction systems—particularly fixed-bed reactor setups requiring ultra-stable, low-flow-rate liquid delivery under extreme pressure conditions. Based on dual-cam-driven, sapphire-hardened ceramic plunger technology, the CP-M305 operates on positive displacement principles to deliver exceptional volumetric accuracy (<±0.3% RSD over 24 h) and pulse-free output across its full flow range (0.001–5 mL/min). Its 60,000 psi (4,137 bar) maximum pressure rating enables compatibility with supercritical fluid applications, high-viscosity feedstocks (e.g., heavy crude fractions, polymer solutions), and dense-phase catalytic environments where backpressure stability directly governs reaction kinetics and catalyst lifetime. Unlike peristaltic or diaphragm-based alternatives, the CP-M305’s mechanically synchronized dual-plunger architecture eliminates flow pulsation and minimizes shear-induced degradation of sensitive reagents—critical for kinetic studies, catalyst deactivation profiling, and long-duration stability testing.
Key Features
- High-pressure capability up to 60,000 psi (4,137 bar), supporting operation in high-backpressure fixed-bed configurations without flow deviation
- Micro-precision flow control from 0.001 mL/min with <±0.3% repeatability (per ISO 5725-2:2019 inter-laboratory precision criteria)
- User-selectable wetted path materials: 316L stainless steel for general corrosion resistance or PEEK for aggressive solvents (e.g., concentrated HCl, HF-containing streams, chlorinated organics)
- Integrated digital interface displaying real-time flow rate, system pressure, programmable pressure upper/lower thresholds, operational mode (run/pause/stop), and fault alerts (e.g., overpressure, plunger stall, seal leakage)
- Modular drive electronics with RS-485 and optional Ethernet/IP connectivity for integration into distributed control systems (DCS) or SCADA platforms
- Compliant with IEC 61000-6-2 (EMC immunity) and IEC 61000-6-4 (EMC emission) standards for use in shared laboratory infrastructure
Sample Compatibility & Compliance
The CP-M305 accommodates a broad spectrum of process fluids—including aqueous acids/bases, organic solvents (THF, DMF, acetonitrile), supercritical CO₂ co-solvent mixtures, and multiphase slurries (with optional filtration pre-stage). Its sealed, oil-free plunger housing prevents cross-contamination and meets ISO 8573-1 Class 0 requirements for oil-free compressed air use in auxiliary actuation. For regulated environments, the pump supports audit-trail-capable operation when paired with validated third-party control software compliant with FDA 21 CFR Part 11 (electronic records/signatures), and aligns with GLP Annex 11 and GMP Annex 11 documentation expectations. It is routinely deployed in ASTM D7213-compliant Fischer–Tropsch catalyst evaluation rigs and ISO 10723:2019-compliant natural gas processing simulation loops.
Software & Data Management
The CP-M305 communicates via Modbus RTU (RS-485 default) or optional TCP/IP protocol, enabling bidirectional parameter exchange with LabVIEW, MATLAB, or custom Python-based orchestration frameworks. When integrated with CoMetro’s optional CMC-Link™ software suite (v3.2+), users gain access to time-stamped event logging, pressure/flow trend overlays, automated calibration certificate generation (traceable to NIST SRM 2800), and electronic signature workflows meeting ALCOA+ data integrity principles. All operational logs include immutable timestamps, operator ID fields, and change history—fully supporting regulatory inspections under EMA Annex 11 and USP analytical instrument qualification protocols.
Applications
- Fixed-bed catalytic reactor feed control for hydrodesulfurization (HDS), ammonia synthesis, and methanol-to-olefins (MTO) studies
- Microreactor and monolithic catalyst evaluation under industrially representative pressure/temperature profiles
- High-pressure liquid chromatography (HPLC) method development for petrochemical fingerprinting
- Supercritical fluid extraction (SFE) and supercritical fluid chromatography (SFC) mobile phase delivery
- Long-term stability testing of heterogeneous catalysts under continuous flow (72+ h runtime validation)
- Corrosion inhibitor injection quantification in simulated downhole environments (API RP 14E-compliant test benches)
FAQ
What is the minimum detectable flow resolution of the CP-M305?
The pump achieves 0.0001 mL/min resolution via 24-bit DAC-controlled stepper motor actuation, enabling precise ramping and dwell control during transient kinetic experiments.
Can the CP-M305 be used with hydrogen sulfide (H₂S)-laden streams?
Yes—when equipped with PEEK fluidic path components and Hastelloy C-276 valve seats, it maintains integrity under 10,000 ppm H₂S at 500°C-equivalent partial pressure per NACE MR0175/ISO 15156 guidelines.
Is remote firmware update supported?
Firmware updates are performed via secure USB-C bootloader mode; network-based updates require on-premise validation per IEC 62443-3-3 SL2 cybersecurity requirements.
How is calibration traceability maintained?
Each unit ships with a factory calibration certificate traceable to NIST SRM 2800 (viscosity standard) and NIST SRM 2196 (pressure standard), valid for 12 months under ISO/IEC 17025-accredited procedures.
Does the pump support fail-safe shutdown on pressure deviation?
Yes—programmable pressure band monitoring triggers immediate stop-and-hold action within ≤100 ms response time, with latching alarm output to external PLC safety relays (IEC 61508 SIL2 certified interface).

