Jihepu IRX60 Research-Grade Inverted Microscope

Overview

The Jihepu IRX60 Research-Grade Inverted Microscope is an integrated opto-mechatronic platform engineered for high-fidelity live-cell imaging and long-term time-lapse observation in life science laboratories. Built upon an infinity-corrected optical architecture with semi-apochromatic objectives and precision-aligned illumination pathways, the IRX60 supports multimodal contrast techniques—including brightfield, phase contrast (PH), differential interference contrast (DIC), and epi-fluorescence—within a single, modular instrument frame. Its inverted configuration enables stable, vibration-resistant imaging of adherent and suspension cultures in standard Petri dishes, multi-well plates, and flasks without specimen inversion or mechanical stress. The system’s core design prioritizes optical fidelity, mechanical stability, and operational reproducibility—critical requirements for quantitative cell biology, developmental studies, and preclinical assay development under controlled environmental conditions.

Key Features

• Modular infinity-corrected optical path with 20°–45° adjustable ergonomic viewing head and interpupillary distance adjustment (50–76 mm)
• High-eyepoint wide-field plan achromat eyepieces (PL10×/22 mm and PL15×/16 mm), both with diopter compensation and optional reticle integration
• Motorized 6-position objective turret with DIC slots and compatibility for long-working-distance semi-apochromatic objectives (2×, 4×, 10×, 20×, 40×, 60×), including phase contrast and relief contrast variants
• Motorized Z-axis focusing system with 10.5 mm total travel and 10 nm resolution display; coarse/fine coaxial focusing mechanism with front-panel status indicators for illumination mode (BF/PH/DIC/FL)
• Dual-layer optical pathway architecture supporting simultaneous fluorescence excitation and transmission imaging; built-in upper and left-side trinocular ports with configurable beam-splitting ratios (0:100 / 50:50 / 100:0)
• Motorized XY stage (114 mm × 75 mm travel range), 0.01 µm step resolution, ±2 µm repeatability, and ≥1.5 mm/s max speed; manual stage option (135 mm × 85 mm) with dual-lock and travel-limiting functions
• 7-hole condenser (NA ≥ 0.55, WD ≥ 27 mm) with dedicated PH (φ30 mm) and DIC (φ38 mm) apertures; vertically adjustable mount with 65 mm stroke and damping tilt mechanism
• 8-position motorized fluorescence filter wheel with position-sensing logic, integrated shutter control, and standardized B1/G1/UV1 filter sets; 100 W mercury arc lamp housing (OSRAM) with dedicated DC power supply
• 12 V / 100 W halogen transmitted-light source (Philips 7724) with pre-centered filament and four manually adjustable filter positions

Sample Compatibility & Compliance

The IRX60 accommodates standard biological sample formats including glass slides, histological sections, culture dishes (Φ110 mm), multi-well plates (6–96-well), and T-flasks—facilitated by its large-stage footprint and low-profile objective clearance. Its phase contrast and DIC modules comply with ISO 8578:2017 for contrast microscopy performance verification. Fluorescence components meet IEC 61000-4-3 EMC immunity standards, while lamp housings conform to IEC 62471 photobiological safety classifications for UV/blue light emission. The system supports GLP-compliant documentation workflows when paired with validated third-party camera systems (e.g., Hamamatsu ORCA-Fusion BT) and audit-trail-enabled acquisition software.

Software & Data Management

The IRX60 is operated via a dedicated research-grade inverted microscope control suite compatible with Windows-based workstations and the integrated 7-inch TPC touchscreen interface. Software features include synchronized motor control (objective turret, Z-focus, filter wheel, shutter), multi-channel fluorescence acquisition with exposure bracketing, time-lapse scheduling with hardware-triggered synchronization, and ROI-based stage navigation. Raw image data is saved in TIFF or OME-TIFF format with embedded metadata (objective ID, magnification, exposure time, filter set, Z-position). Export options include CSV-compatible measurement logs for morphometric analysis and direct integration with ImageJ/Fiji, MATLAB, and Python-based analysis pipelines via documented API hooks.

Applications

The IRX60 serves as a foundational imaging platform across multiple life science domains: long-term live-cell tracking in proliferation and migration assays; real-time monitoring of organelle dynamics using fluorescent protein tags; routine quality control of stem cell cultures and primary isolates; quantitative phase contrast analysis of unstained monolayers; DIC-based subcellular structural visualization in thick specimens; and multiplexed fluorescence co-localization studies requiring precise Z-stack acquisition. Its robust mechanical design and thermal stability make it suitable for integration into incubator-equipped imaging chambers (37 °C, 5% CO₂) for extended-duration experiments.

FAQ

Is the IRX60 compatible with third-party scientific cameras?
Yes—the system provides standard C-mount interfaces (0.5×, 0.65×, and 1× TV adapters) and supports USB 3.0/PCIe-based cameras from Hamamatsu, QImaging, and舜宇 (Sunny Optical), with full trigger and gain control via the host software.

Can the IRX60 be upgraded to support confocal or TIRF modalities?
No—the IRX60 is a widefield-only platform. Confocal or TIRF capabilities require external laser scanning units or objective-type TIRF modules not natively supported by the IRX60 optical train or firmware.

Does the motorized stage support closed-loop feedback positioning?
The standard XY stage uses open-loop stepper motors. Closed-loop encoders are not included but may be retrofitted via OEM collaboration upon request.

What regulatory documentation is provided for laboratory validation?
Factory calibration reports, optical alignment certificates, and CE Declaration of Conformity are supplied. FDA 21 CFR Part 11 compliance is achievable through optional software validation packages and electronic signature modules.

Is service and technical support available outside mainland China?
Jihepu maintains authorized service partners in Southeast Asia, the Middle East, and Eastern Europe. Remote diagnostics and firmware updates are supported via secure VPN channels.