Autosense MTN-5800D Electric Nitrogen Evaporator

Overview

The Autosense MTN-5800D Electric Nitrogen Evaporator is an engineered solution for controlled, solvent-free concentration of multiple liquid samples under inert nitrogen atmosphere. Designed around the principle of gentle, uniform heat transfer via thermostatically regulated water bath and precisely directed laminar nitrogen flow, this instrument enables reproducible evaporation of volatile organic solvents—such as acetonitrile, methanol, ethyl acetate, and hexane—from biological extracts, environmental samples, pharmaceutical formulations, and food matrices. Its dual-sample-capacity architecture (12- or 24-position configurations), combined with electrically actuated vertical motion systems and real-time liquid-level tracking, supports high-throughput workflows while maintaining analytical integrity across diverse container geometries—including conical centrifuge tubes, round-bottom vials, culture tubes, and small-volume beakers.

Key Features

• Electric Dual-Axis Motion Control: Motorized lifting of both the needle manifold (135–235 mm travel) and sample tray (0–100 mm travel) ensures ergonomic access during loading/unloading and accommodates variable vessel heights without manual repositioning.
• Auto-Level Tracking System: The nitrogen delivery needles descend synchronously with the receding solvent meniscus, minimizing sample splashing, oxidation, and analyte loss—critical for thermolabile compounds and low-concentration standards.
• Dual-Mode Sample Holder: A rotatable, calibrated 360° sample disc allows rapid alignment of tubes or beakers under individual nozzles. For the 12-position configuration, a precision-machined collar with engraved scale and mechanical lock adjusts aperture from Φ30 to Φ55 mm; the 24-position version accepts tubes from Φ10 to Φ29 mm.
• Independent Needle Flow Regulation: Each of the 12 or 24 stainless-steel or disposable polymer nozzles features a digitally indexed flow valve, enabling consistent, repeatable gas delivery across all channels—essential for inter-sample comparability in quantitative LC-MS or GC-MS preparation.
• PID-Controlled Water Bath: A 1000 W heating element maintains temperature stability within ±0.2 °C across the full operating range (ambient to 96 °C), verified by integrated platinum RTD sensing and validated against ASTM E2251-22 thermal uniformity criteria.
• Safety & Maintenance Engineering: An ultrasonic water level sensor triggers audible/visual alarms and cuts power to the heater upon low-fluid detection. A front-access drain valve facilitates rapid tank emptying; the transparent acrylic bath permits visual monitoring of sample status and condensate accumulation.

Sample Compatibility & Compliance

The MTN-5800D accommodates a broad spectrum of laboratory vessels: microcentrifuge tubes (1.5–15 mL), culture tubes (13–18 mm OD), conical-bottom vials (up to 50 mL), and shallow beakers (Φ30–55 mm). Its modular adapter design eliminates need for third-party accessories. From a regulatory perspective, the system supports GLP-compliant documentation when paired with validated SOPs—particularly relevant for residual solvent analysis per ICH Q3C guidelines. While not FDA 21 CFR Part 11–certified out-of-the-box, its deterministic control logic, non-volatile parameter storage, and audit-ready event logging (via optional RS232/USB interface) align with data integrity expectations in pharmaceutical QC labs.

Software & Data Management

The MTN-5800D operates via an embedded microcontroller with backlit LCD interface displaying real-time bath temperature, setpoint, gas flow rate, and system status. All parameters—including ramp profiles, hold times, and flow presets—are stored in non-volatile memory. Though standalone operation is standard, optional serial communication (RS232) enables integration into LIMS or ELN environments for automated run logging and electronic batch records. No proprietary software installation is required; ASCII-based command protocols allow direct scripting via Python or LabVIEW for lab automation pipelines.

Applications

• Pre-concentration of pesticide residues in soil/water extracts prior to GC-ECD or LC-MS/MS analysis (per EPA Method 525.3 and ISO 17025 requirements)
• Removal of derivatization reagents (e.g., BSTFA, PFPA) following silylation or acylation steps in steroid or fatty acid profiling
• Parallel concentration of plasma, urine, or tissue homogenates in clinical toxicology screening workflows
• Final solvent exchange in nanoparticle synthesis (e.g., PLGA encapsulation) where residual DCM or chloroform must be reduced to <50 ppm
• High-throughput cleanup of QuEChERS extracts prior to multi-residue pesticide quantification

FAQ

Is the MTN-5800D compatible with corrosive solvents such as hydrochloric acid or trifluoroacetic acid?

No. The water bath, stainless-steel needle assembly, and internal seals are rated for common organic solvents only. Exposure to strong mineral acids or halogenated agents may compromise material integrity and void warranty.
Can the instrument maintain temperature uniformity across all 24 positions simultaneously?

Yes. Thermal mapping per ASTM E2251-22 confirms ≤±0.3 °C deviation across the bath surface at 60 °C, provided vessels are evenly distributed and filled to comparable volumes.
What is the recommended nitrogen supply pressure for optimal performance?

A regulated inlet pressure of 0.2–0.3 MPa (30–45 psi) ensures stable flow through the float meter and needle valves across the full 0–25 L/min range.
Does the system support external temperature probe input for sample-in-vial monitoring?

Not natively. However, the bath temperature correlates strongly with sample temperature under standardized conditions (e.g., 1.5 mL in 15 mL tubes at 40 °C); empirical calibration curves can be established for critical applications.
How often should the water bath be cleaned and refilled?

Daily replacement is advised for high-throughput labs. For extended use, deionized water with biocide additive (e.g., 0.01% sodium azide) may extend service intervals to 72 hours—subject to local safety protocols.