Caleva
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| Brand | Caleva |
|---|---|
| Origin | United Kingdom |
| Model | CML |
| Type | Benchtop Integrated Pharmaceutical Process Development Instrument |
| Construction | 304 Stainless Steel Frame |
| Product-Contact Parts | 316/316L Stainless Steel & POM (Polyoxymethylene) |
| Batch Capacity | 10–25 g (dry weight), up to 50 g (wet weight) |
| Granulator Bowl Options | Full-height & semi-bowl (enables 20 g dry-weight minimum batch) |
| Extruder | Continuous operation |
| standard die plate | Ø1.0 mm × 1 mm depth (interchangeable: 0.5–3.0 mm) |
| Spheronizer Bowl Capacity | 10–80 g (wet weight) |
| Drive Speed Control | Analog potentiometer with digital RPM display (switchable between granulator shaft, extruder screw, and spheronizer disc speeds) |
| Safety | Interlocked CE-compliant safety guard |
| Dimensions (base unit) | 450 × 365 × 375 mm |
| Weight | 34.25 kg |
| Compliance | CE-marked |
| Brand | Caleva |
|---|---|
| Origin | United Kingdom |
| Model | Extruder-20 |
| Throughput | 10 g/hr to 20 kg/hr |
| Screen Options | Full-height and half-height screens (0.8 mm, 1.0 mm, 1.2 mm aperture) |
| Compliance | Designed for pharmaceutical development and scale-up validation per ICH Q5A/Q5C, FDA 21 CFR Part 11–ready configuration available |
| Brand | Caleva |
|---|---|
| Origin | United Kingdom |
| Model | MBS-120 Spheronizer |
| Drum Diameter Range | 70–120 mm |
| Batch Capacity | 10–150 g |
| Dimensions (W×D×H) | 250 × 200 × 420 mm |
| Weight | 15 kg |
| Contact Materials | 316 stainless steel, acrylic |
| Drive | High-power DC motor with thyristor speed controller |
| Speed Control | 10-turn uncalibrated potentiometer + handheld tachometer |
| Standard Inserts | Two cross-hatched discs (3 mm and 6 mm pitch) |
| Power Supply | Single-phase |
| Brand | Caleva |
|---|---|
| Origin | United Kingdom |
| Manufacturer Type | Authorized Distributor |
| Origin Category | Imported |
| Model | MBS-250 Spheronizer |
| Pricing | Upon Request |
| Brand | Caleva |
|---|---|
| Origin | United Kingdom |
| Model | MCC |
| Power Supply | 230 V AC, 50 Hz |
| Weight | 20 kg |
| Dimensions (W × D × H) | 490 × 560 × 400 mm |
| Temperature Range | 25–60 °C |
| Compressed Air Requirement | 0.3–0.6 MPa, 3.6 m³/h |
| Enclosure IP Rating | IP31 |
| Product Contact Materials | ASTM F86-compliant 316 stainless steel, FDA-listed plastics, borosilicate glass |
| Non-Contact Housing | Polyurethane-coated 304 stainless steel |
| Touchscreen Interface | 7-inch capacitive LCD with intuitive slider-based parameter control |
| Peristaltic Pump Flow Rate | 15–60 mL/h |
| Coating Capacity | 1 tablet to 150 tablets (~50 g), 1 capsule to batch of capsules, 1 g to ~60 g microspheres (≥400 µm) |
| Typical Coating Duration | 15–30 min |
| Compliance | CE-marked, designed per IEC 61000-6-2/6-4 and EN 61000-6-3 |
| Software | MCC v1.01 with real-time logging, parameter recall, and audit-ready event history |
| Brand | Caleva |
|---|---|
| Origin | United Kingdom |
| Model | MLS |
| Voltage | 230 V or 110 V |
| Touchscreen | 7-inch capacitive LCD |
| Data Interface | 2 × USB 3.0, 2 × USB 2.0 |
| Machine Weight | 34 kg |
| Dimensions (W × D × H) | 505 × 600 × 420 mm |
| Mixing Capacity | 15–40 g (30–80 mL) |
| Extrusion Capacity | 10–80 g |
| Spheronization Capacity | 10–80 g |
| Main Impeller Speed | 10–250 rpm |
| Extruder Screw Speed | 90–150 rpm |
| Spheronizer Disc Speed | 500–4500 rpm |
| Die Orifice Standard | Ø1.0 mm × 1.0 mm square |
| Optional Dies | Ø0.5–3.0 mm round, multi-lobed profiles, variable thickness |
| Standard Spheronization Disc | 3 × 3 mm cross-hatched |
| Temperature Monitoring | Ambient & process zone |
| Motor Load Monitoring | 0–100% real-time reporting |
| Microscopy | Integrated USB digital microscope |
| Compliance Support | GLP-aligned data integrity, audit-trail-ready operation |
| Brand | Caleva |
|---|---|
| Origin | United Kingdom |
| Model | MTR3 |
| Maximum Batch Volume | 20 L |
| Speed Range | 0–1500 rpm |
| Temperature Control | Ambient only |
| Power Supply | Single-phase, 110–240 V AC |
| Dimensions (W × D) | ~400 × 500 mm |
| Weight | ~35 kg |
| Software Interface | PC-based via RS-232 or USB |
| Compliance Options | 21 CFR Part 11 software upgrade available |
| Brand | Caleva |
|---|---|
| Origin | United Kingdom |
| Model | VDE (Variable-Density Extruder) |
| Extrusion Orientation | Radial & Axial |
| Die Orifice Diameter Range | 0.2–2.0 mm |
| Die Orifice Depth Range | 0.5–6.0 mm (radial), 0.5–8.0 mm (axial) |
| Max. Throughput | 27 kg/hr (radial), 20 kg/hr (axial) |
| Construction Material | 316 Stainless Steel (all product-contact parts) |
| Thermal Control | Standard insulated jacketed barrel with heating/cooling capability |
| Safety | Full interlock system, tool-free cleaning design |
| Compliance | Designed for GLP-compliant R&D environments |
