Agilent 7890A-5975C (G3172A) GC-MS System
| Brand | Agilent Technologies |
|---|---|
| Origin | Canada |
| Model | 7890A-5975C (G3172A) |
| Instrument Type | Gas Chromatography–Mass Spectrometry (GC-MS) |
| Mass Analyzer | Quadrupole |
| Detector | Triple-Axis Electron Multiplier |
| Mass Range | 1.6–1050 u |
| Scan Speed | Up to 12,000 u/sec |
| Sensitivity | 1 pg OFN (octafluoronaphthalene), S/N ≥ 400:1 (m/z 272) |
| Operating Age | 3–4 years |
| Compliance | Fully Functional per Agilent G3172A Specification |
| Warranty | Not Included |
Overview
The Agilent 7890A-5975C (G3172A) GC-MS System is a reconditioned, fully validated benchtop gas chromatography–mass spectrometry platform engineered for high-fidelity qualitative and quantitative analysis in regulated and research environments. This integrated system couples the Agilent 7890A gas chromatograph—featuring precision electronic pneumatic control (EPC) and programmable temperature ramping—with the Agilent 5975C inert Mass Selective Detector (MSD), which employs a triple-axis electron multiplier for enhanced signal-to-noise ratio and improved spectral fidelity. The quadrupole mass analyzer delivers unit-mass resolution across a 1.6–1050 u mass range, enabling robust compound identification and trace-level detection in complex matrices. Designed for reproducibility and method transferability, the system supports both full-scan and selected ion monitoring (SIM) acquisition modes, with scan speeds up to 12,000 u/sec—critical for coupling with fast GC gradients or narrow peak elution profiles.
Key Features
- Agilent 7890A GC platform with dual independent EPC modules for simultaneous control of inlet pressure, column flow, and detector gases—ensuring retention time stability < ±0.02 min over 24 h
- 5975C inert MSD featuring chemically passivated ion source and triple-axis electron multiplier for reduced memory effects and extended source lifetime
- Standard EI (electron ionization) mode with optional CI (chemical ionization) capability via field-replaceable ion source kit
- Integrated GC oven with rapid heating/cooling rates (up to 120 °C/min) and precise isothermal hold accuracy (±0.1 °C)
- Autotune functionality compliant with Agilent G3172A factory specifications; includes mass calibration verification at m/z 502, 614, and 726
- Fully reconditioned and functionally verified by SpectraLab Scientific—including leak testing, vacuum integrity assessment (< 5×10⁻⁶ Torr base pressure), and performance validation using certified standards (e.g., EPA 8270D surrogate mix)
Sample Compatibility & Compliance
The 7890A-5975C system is compatible with volatile and semi-volatile organic compounds (VOCs/SVOCs), pesticides, PAHs, PCBs, residual solvents, and environmental contaminants. It supports standard 0.25–0.53 mm ID capillary columns (e.g., DB-5ms, HP-5MS, VF-WAXms) and accommodates split/splitless, PTV, and cold-on-column injection techniques. The instrument meets functional requirements aligned with ASTM D5845, EPA Methods 524.2, 8260D, and 8270D, and supports audit-ready data acquisition under GLP/GMP conditions when paired with compliant software (e.g., MassHunter Workstation vB.08.x or later). While the hardware itself does not carry active manufacturer warranty, its operational compliance with original Agilent G3172A technical specifications has been confirmed through third-party certification.
Software & Data Management
Data acquisition and processing are performed using Agilent MassHunter Workstation Software (licensed separately), supporting real-time spectral deconvolution, library search (NIST/EPA/WHO), quantitative calibration curves (linear/non-linear), and customizable report generation. The system architecture supports 21 CFR Part 11-compliant configurations when deployed with appropriate network policies, user access controls, and electronic signature workflows. Raw data files (.D format) are fully interoperable with OpenLab CDS and third-party chemometric tools. All firmware versions installed during reconditioning are stable, vendor-approved releases—no beta or unsupported patches are deployed.
Applications
This GC-MS system is routinely applied in environmental testing laboratories for water, soil, and air analysis; in pharmaceutical QC for residual solvent quantitation (ICH Q3C); in food safety labs for pesticide residue screening (EU MRLs); and in forensic toxicology for controlled substance identification. Its sensitivity (1 pg OFN, S/N ≥ 400:1 at m/z 272) and spectral reproducibility make it suitable for method development, regulatory submission support, and routine compliance testing where data integrity and traceability are mandated.
FAQ
Is this instrument covered by Agilent’s original factory warranty?
No—the unit is sold as-is with no remaining Agilent warranty. However, it has undergone full functional reconditioning and certification by SpectraLab Scientific.
What documentation is provided with the system?
A comprehensive reconditioning report, vacuum integrity log, autotune summary, and performance verification data against EPA 8270D standards are included.
Can this system be upgraded to support SIM/Scan hybrid methods?
Yes—firmware and MassHunter software support dynamic SIM/Scan switching within a single sequence, provided the installed software version is B.07.00 or higher.
Is installation and on-site qualification included?
Installation, basic commissioning, and IQ/OQ documentation support are available as optional services—contact SpectraLab Scientific for regional service agreements.
Does the system include a computer and software license?
No—MassHunter Workstation software requires a separate, valid Agilent license. A dedicated Windows 10/11 workstation meeting Agilent’s minimum hardware specifications must be supplied by the end user.
