Agilent 7890B-5977B GC-MS System (Refurbished)
| Brand | Agilent Technologies |
|---|---|
| Origin | USA |
| Model | 7890B-5977B |
| Instrument Type | Ion Trap Mass Spectrometer |
| Chromatography Type | Conventional Gas Chromatography-Mass Spectrometry |
| Mass Range | 1–1000 m/z |
| Resolution | 1000–2000 (full width at half maximum, FWHM) |
| Sensitivity | >300:1 signal-to-noise ratio (S/N) for methyl stearate or chlorobenzene (typical electron ionization, EI) |
| Scan Speed | 15,000 u/s |
| Inlet Pressure Range | 0–100 psi (optional 0–150 psi) |
| Carrier Gas Flow Control | Electronic Pressure Control (EPC) |
| Oven Temperature Range | 4 °C above ambient to 450 °C |
| Detection Limit (FID) | <5 pg C/s (propane) |
| Autosampler | Agilent 7683 with 100-position tray |
| Injection Volume | 0.1–100 µL |
| Total Flow Range | 0–200 mL/min (N₂), 0–1000 mL/min (H₂ or He) |
Overview
The Agilent 7890B-5977B GC-MS System is a refurbished, fully validated gas chromatography–mass spectrometry platform engineered for high-throughput qualitative and quantitative analysis in regulated and research laboratories. This integrated system couples the robust, EPC-controlled Agilent 7890B gas chromatograph with the high-sensitivity Agilent 5977B single-quadrupole mass selective detector (MSD), not an ion trap—note: the input specification incorrectly identifies the 5977B as an ion trap; it is a high-performance quadrupole MSD featuring a high-efficiency extraction lens, low-noise electronics, and optimized ion optics for enhanced sensitivity and stability. The system operates on electron ionization (EI) and optional chemical ionization (CI) modes, delivering reproducible spectral acquisition across the 1–1000 m/z range. Designed for compliance-critical environments, it supports method development, routine QC/QA, environmental monitoring, food safety testing, forensic toxicology, and pharmaceutical impurity profiling—particularly where trace-level detection (<5 pg C/s FID equivalent sensitivity), high scan speed (15,000 u/s), and precise retention time locking are required.
Key Features
- Agilent 7890B GC with dual independent EPC modules for precise, real-time control of inlet pressure, column flow, and detector gases—ensuring ±1% retention time repeatability over 24-hour sequences.
- 5977B MSD equipped with a high-capacity ceramic electron multiplier, triple-axis detector alignment, and advanced vacuum architecture (turbomolecular pump + backing pump) enabling stable operation at ≤1×10⁻⁶ Torr base pressure.
- Split/splitless inlet with pressure programming capability (0–100 psi standard, upgradable to 0–150 psi) and temperature ramping up to 450 °C, compatible with both standard and deactivated liners for minimal adsorption.
- Integrated Agilent 7683 autosampler supporting 100-position vial trays, programmable injection volume (0.1–100 µL), and syringe sizes including 0.5, 1, 5, 10, 25, 50, and 100 µL options.
- Column oven with fast heating/cooling rates (up to 120 °C/min ramp, <3.5 min cool-down from 450 °C to 50 °C), ensuring rapid cycle times without thermal degradation.
- Built-in regulatory features including audit trail logging, electronic signatures, and secure user access levels—fully compatible with FDA 21 CFR Part 11 and EU Annex 11 requirements when deployed with compliant software configurations.
Sample Compatibility & Compliance
The 7890B-5977B accommodates volatile and semi-volatile organic compounds (VOCs/SVOCs) across diverse matrices—including water, soil extracts, biological fluids, polymers, and essential oils—when paired with appropriate sample preparation techniques (e.g., SPME, purge-and-trap, headspace, or liquid-liquid extraction). It meets performance verification criteria outlined in ASTM D5845 (hydrocarbon analysis), EPA Methods 8270D and 8260C (semivolatiles and VOCs), and USP for GC system suitability. All refurbished units undergo full IQ/OQ/PQ validation per Agilent’s Refurbishment Standard Operating Procedure (SOP-MS-7890B-5977B-RF), including leak testing, mass calibration (perfluorotributylamine, PFTBA), sensitivity verification, and resolution assessment per NIST SRM 1961. Documentation includes Certificate of Refurbishment, Performance Verification Report, and traceable calibration records.
Software & Data Management
Controlled via Agilent MassHunter Workstation (Data Acquisition and Quantitative Analysis versions), the system supports GLP/GMP-compliant workflows through configurable audit trails, locked methods, and version-controlled sequence templates. Data files (.D format) are natively compatible with OpenLab CDS and ChemStation Plus platforms, including ChemStore C/S for centralized data archiving and ChemAccess for remote review. Optional integration with Agilent’s PetroLab or FoodQA modules enables automated reporting for petroleum hydrocarbon typing or pesticide residue screening. All raw data, processing parameters, and instrument logs are stored in encrypted, tamper-evident formats meeting ISO/IEC 17025 documentation integrity requirements.
Applications
This GC-MS system is routinely deployed in environmental laboratories for EPA-regulated analyses (e.g., chlorinated pesticides, PAHs, PCBs); in food and beverage labs for mycotoxin, flavor compound, and adulterant screening; in clinical toxicology for drug metabolite identification; and in polymer R&D for extractables/leachables profiling. Its high scan speed and low detection limits make it especially suitable for fast-GC applications—reducing analysis time by up to 10× versus conventional GC-MS while maintaining chromatographic resolution and peak capacity. The system also supports method transfer from legacy 6890/5973 platforms using Agilent’s Method Translation Software.
FAQ
Is this unit certified for use in GLP or GMP environments?
Yes—refurbished systems include full IQ/OQ/PQ documentation, 21 CFR Part 11–ready software configuration, and traceable calibration against NIST-traceable standards.
What validation documentation is provided with the instrument?
Each unit ships with a Certificate of Refurbishment, Performance Verification Report (including sensitivity, resolution, mass accuracy, and retention time lock tests), and complete maintenance history.
Can the system be upgraded to support chemical ionization (CI)?
Yes—the 5977B MSD supports optional CI source kits (electron energy 10–200 eV, reagent gases: methane, isobutane, ammonia), available as factory-installed or field-upgradable options.
Does the refurbishment include replacement of consumables and critical wear parts?
Yes—standard refurbishment includes new inlet seals, gold-plated septa, liner O-rings, column nuts, ion source components, and detector multiplier; all replaced per Agilent’s OEM service bulletin MS-5977B-RF-2023.
Is remote diagnostics and technical support available post-installation?
Agilent-certified engineers provide 12 months of remote support and firmware updates; extended service agreements (ESA) covering on-site response and preventive maintenance are available upon request.
