Chemyx Fusion 100-X Dual-Channel Syringe Pump

Overview

The Chemyx Fusion 100-X is a high-precision, dual-channel syringe pump engineered for microfluidic control in research-intensive laboratory environments. It operates on a stepper motor-driven linear actuation principle, converting rotational motion into highly resolved translational displacement of syringe plungers—enabling precise volumetric delivery across an exceptionally wide dynamic flow range. Designed for applications demanding strict volumetric fidelity and temporal reproducibility—including gradient elution in HPLC, reagent dosing in automated synthesis platforms, and controlled infusion in organ-on-chip or electrophysiology setups—the Fusion 100-X delivers deterministic flow profiles with minimal pulsation and thermal drift. Its modular architecture supports expansion to up to 11 independent syringes via optional multi-syringe mounting brackets, facilitating complex multi-reagent protocols without requiring system-level reconfiguration.

Key Features

• Dual independent channels with synchronized or asynchronous operation modes, each supporting real-time flow rate adjustment without interrupting ongoing infusions.
• Ultra-broad flow range spanning six orders of magnitude—from nanoliter-per-minute precision (0.0001 µL/min) to milliliter-scale throughput (157 mL/min)—achievable with a single instrument platform.
• High-force linear actuator (25 kg / 55 lb) compatible with glass, polypropylene, and stainless-steel syringes ranging from 0.5 µL micro-capillary barrels to standard 60 mL Luer-lock reservoirs.
• 4.3-inch full-color capacitive touchscreen interface with intuitive icon-driven navigation, onboard parameter logging, and real-time graphical flow profile visualization.
• Native support for USB-B, RS232, and TTL digital I/O interfaces—enabling seamless integration into LabVIEW, Python-based automation frameworks, and PLC-controlled analytical workflows.
• Robust mechanical design certified for continuous-duty operation under ambient laboratory conditions (20–25°C, 30–70% RH), with ESD-safe housing and CE-compliant electromagnetic compatibility.

Sample Compatibility & Compliance

The Fusion 100-X accommodates all commercially available Luer-lock and Luer-slip syringes constructed from borosilicate glass, medical-grade polypropylene, or chemically resistant PTFE-lined variants. It is routinely deployed in GLP-compliant assay development labs and FDA-regulated preclinical formulation studies where traceable, auditable fluid handling is required. While the device itself does not carry FDA 510(k) clearance as a medical device, its firmware architecture supports audit-trail-enabled operation when paired with compliant host software—meeting foundational requirements for 21 CFR Part 11 data integrity in regulated QC/QA environments. The pump conforms to ISO 8536-4 (syringes for medical use) dimensional tolerances and ASTM D3418 (thermal transitions of polymers) testing prerequisites when used in polymer solution rheology or solvent exchange protocols.

Software & Data Management

Chemyx provides the proprietary Fusion Series Software Suite (v4.2+), a Windows-native application supporting method creation, multi-step ramp/step/pulse protocols, real-time monitoring, and CSV export of timestamped flow, pressure (when used with optional inline sensors), and status logs. The software implements role-based user access controls, electronic signature capture, and configurable data retention policies aligned with ALCOA+ principles. For enterprise integration, RESTful API endpoints and SCPI command sets are documented and maintained—allowing direct orchestration within Thermo Fisher SampleManager, Waters Empower, or custom LIMS deployments. All firmware updates undergo regression-tested validation and are distributed with SHA-256 checksums and versioned release notes.

Applications

• Controlled reagent addition in catalytic reaction screening and continuous-flow chemistry reactors.
• Gradient generation for liquid chromatography method development and column equilibration.
• Cell culture media perfusion in 3D bioreactors and microphysiological systems.
• Calibration fluid delivery in gravimetric and photometric analytical standards preparation.
• Micro-injection in zebrafish embryo studies and patch-clamp electrophysiology.
• Viscoelastic sample loading in micro-rheometry and interfacial tension measurement cells.

FAQ

Does the Fusion 100-X support syringe calibration for different barrel materials and diameters?
Yes—users can define custom syringe geometry profiles (inner diameter, plunger travel length, material compliance factor) to compensate for mechanical hysteresis and compressibility effects across glass, plastic, and metal syringes.
Can it operate unattended for extended durations (e.g., >72 hours)?
Yes—validated for continuous operation up to 168 hours at mid-range flow rates (1–10 mL/min) with no performance degradation; thermal management includes passive heat dissipation and duty-cycle-aware motor current regulation.
Is remote monitoring possible over Ethernet or Wi-Fi?
The base model features USB-B and RS232 only; Ethernet/Wi-Fi connectivity requires an external serial-to-Ethernet converter or integration via a host PC running the Fusion Software Suite with network-shared access enabled.
What maintenance intervals are recommended for long-term accuracy retention?
Chemyx recommends biannual verification using NIST-traceable gravimetric flow standards; lubrication of lead screws is not required due to sealed pre-lubricated linear rail design.
Are replacement parts and service manuals available internationally?
Yes—authorized distributors provide global access to OEM spare kits (motor assemblies, display modules, power supplies), and full technical documentation—including schematics and firmware recovery procedures—is available under NDA to qualified service partners.