Chengmeng THZ-C-L Benchtop Refrigerated Orbital Shaker

Overview

The Chengmeng THZ-C-L Benchtop Refrigerated Orbital Shaker is an engineered platform for precise temperature-controlled agitation of biological and biochemical samples in research laboratories, quality control environments, and bioprocess development settings. It operates on the principle of orbital shaking—generating a consistent circular motion with fixed 26 mm amplitude—to ensure homogeneous suspension, efficient oxygen transfer, and reproducible culture conditions for microbial, mammalian, and yeast cell growth. Integrated refrigeration enables active cooling down to 5 °C, extending operational utility beyond ambient-limited shakers and supporting temperature-sensitive applications such as enzyme kinetics, protein expression at low temperatures, and cold-adapted strain cultivation. Its robust steel frame, insulated chamber, and PID-driven intelligent temperature controller deliver stable thermal performance across diverse climatic conditions—mitigating overshoot and drift commonly observed in non-compensated systems.

Key Features

• Orbital motion with adjustable speed from 40 to 300 rpm, calibrated and repeatable within ±1 rpm tolerance
• Fixed 26 mm orbit diameter optimized for uniform mixing and minimal shear stress on sensitive cells
• Active refrigeration system enabling operation from 5 °C to 60 °C; maintains setpoint stability even under load and ambient fluctuations
• PID-based digital temperature controller with ±0.1 °C accuracy and ±0.5 °C uniformity across the platform surface
• Single large-format stainless-steel platform (capable of holding up to six 1000 mL Erlenmeyer flasks or twenty 250 mL vessels)
• Programmable timer with 0–999 minute range, supporting unattended overnight or extended incubation protocols
• 600 W high-efficiency motor and thermoelectric cooling assembly designed for continuous-duty operation
• Front-accessible control panel with intuitive LED display, real-time parameter monitoring, and user-configurable ramp profiles

Sample Compatibility & Compliance

The THZ-C-L accommodates standard laboratory glassware and plastic vessels including baffled and non-baffled flasks, test tubes, microplates (with optional adapter), and culture bottles. Its platform geometry supports universal clamping accessories compatible with common flask sizes (e.g., 125–2000 mL). The unit complies with IEC 61010-1:2010 safety standards for electrical equipment used in laboratory environments. While not certified for GMP manufacturing use out-of-the-box, its programmable logging capability, stable thermal profile, and traceable timer functionality align with GLP documentation requirements. Temperature calibration can be verified using NIST-traceable probes, and users may implement internal SOPs for periodic verification per ISO/IEC 17025 guidelines.

Software & Data Management

This model features embedded firmware without external PC connectivity; however, all operational parameters—including speed, temperature, time, and run status—are digitally recorded in non-volatile memory. A built-in event log stores the last 20 run cycles with timestamps, setpoints, and end conditions—accessible via the front panel menu. For laboratories requiring electronic records, optional RS-232 or USB-to-serial interface modules (sold separately) enable integration with LIMS or custom data acquisition software. The controller supports password-protected parameter locking to prevent unauthorized changes—a basic safeguard aligned with FDA 21 CFR Part 11 principles for audit-ready workflows.

Applications

• Microbial and fungal culture expansion under controlled hypothermic or mesophilic conditions
• Recombinant protein expression in E. coli and Pichia pastoris at inducible temperatures (e.g., 16–25 °C)
• Enzyme activity assays requiring precise thermal management during kinetic measurements
• Cell lysis optimization via gentle agitation combined with cold buffer conditions
• Preparation of homogeneous suspensions for downstream analysis (e.g., flow cytometry, qPCR template prep)
• Stability testing of biologics and formulations under accelerated thermal cycling protocols

FAQ

Does the THZ-C-L support both heating and cooling functions?

Yes—it integrates resistive heating and thermoelectric (Peltier) cooling to achieve full-range temperature control from 5 °C to 60 °C.
Can the shaker maintain temperature stability when multiple large flasks are loaded?

Yes—the chamber insulation, forced-air convection design, and adaptive PID algorithm ensure ±0.5 °C uniformity across the platform even at maximum load (6 × 1000 mL).
Is the timer function capable of auto-restart after power interruption?

No—the device does not retain timer state during power loss; however, temperature and speed settings persist in memory and resume upon reboot.
What maintenance is required for long-term reliability?

Annual inspection of fan filters, condenser coil cleaning, and verification of platform leveling and drive belt tension (if applicable) are recommended per manufacturer service guidelines.
Are third-party flask clamps or microplate adapters available?

Yes—standardized M6-threaded mounting holes on the platform allow compatibility with OEM and aftermarket accessories meeting ISO 8573-1 mechanical interface specifications.