Chu Ding Technology DL-2000 2000 mL Solvent Filtration Assembly with Fritted Glass Filter

Overview

The Chu Ding Technology DL-2000 Solvent Filtration Assembly is a precision-engineered vacuum filtration system designed specifically for high-purity solvent preparation in analytical chromatography laboratories. It operates on the principle of pressure differential-driven filtration through a sintered glass frit—typically grade G3 (15–40 µm) or G4 (5–15 µm)—to remove particulate contaminants, undissolved residues, and micro-aggregates from HPLC-grade mobile phases. Unlike membrane-only filtration units, this assembly integrates both mechanical particulate retention and passive vacuum-assisted degassing, reducing dissolved gas content in solvents prior to LC system introduction. This dual functionality helps mitigate baseline noise, bubble formation in pumps and detectors, and premature column fouling—critical factors in achieving reproducible retention times and peak symmetry in isocratic or gradient separations.

Key Features

• Robust borosilicate glass (DIN/ISO 3585 Type 3.3) construction ensures uniform wall thickness, high thermal shock resistance (up to 270 °C), and excellent chemical compatibility with organic solvents (e.g., acetonitrile, methanol, THF), aqueous buffers, and dilute acids/bases.
• Modular design includes a calibrated 2000 mL conical collection flask (with volume markings), a standard 50 mm diameter sintered glass filter disc (G3/G4), a 300 mL graduated filtration funnel with PTFE-sealed ground-glass joint, and a stainless-steel locking clamp for secure vacuum-tight assembly.
• Ground-glass joints conform to ISO 2955 (24/29 or 29/32 taper options available), enabling seamless interoperability with vacuum manifolds, vacuum controllers, and filtration accessories from major international suppliers (e.g., Thermo Fisher, VWR, DWK Life Sciences).
• No internal gaskets or polymer components contact the filtrate—eliminating leaching risks and ensuring compliance with USP , ICH Q5C, and ISO 15189 method validation requirements for trace-level analysis.
• Designed for integration with regulated laboratory environments: compatible with vacuum pressure logging, audit-trail-capable vacuum controllers, and GLP-compliant documentation workflows.

Sample Compatibility & Compliance

The DL-2000 assembly supports filtration of all common HPLC and UHPLC mobile phase components—including water, methanol, ethanol, acetonitrile, tetrahydrofuran, isopropanol, and buffered aqueous solutions (pH 2–10). It is not intended for strong oxidizers (e.g., concentrated nitric acid), hydrofluoric acid, or molten alkalis. The sintered glass frit is autoclavable (121 °C, 20 min) and resistant to repeated cleaning with chromic acid or piranha solution (with appropriate safety protocols). All glass components meet DIN EN ISO 1042 volumetric accuracy standards for Class B tolerance. The system complies with general laboratory safety standards per ISO 15195 and supports adherence to FDA 21 CFR Part 11 when paired with validated vacuum control hardware and electronic logbook systems.

Software & Data Management

While the DL-2000 is a manual vacuum filtration device without embedded electronics, its physical design enables full traceability within digital lab infrastructure. Volume graduations on the collection flask allow direct recording into ELN platforms (e.g., LabArchives, Benchling). When used with programmable vacuum controllers (e.g., Vacuubrand PC 3001 Vario), real-time pressure, duration, and cycle count data can be exported via RS232/USB for inclusion in analytical method files. The absence of firmware or onboard memory simplifies 21 CFR Part 11 compliance—no electronic records are generated unless external instrumentation is employed.

Applications

• Pre-filtration and inline degassing of HPLC/UHPLC mobile phases prior to pump inlet and autosampler injection.
• Preparation of particle-free solvents for UV-Vis spectroscopy, Karl Fischer titration, and dissolution testing per USP <<711>.
• Clarification of stock solutions containing salts, polymers, or surfactants before syringe filtration or sterile filtration steps.
• Recovery and reuse of spent mobile phases in cost-sensitive QC/QA labs—subject to post-filtration verification by light obscuration or sub-2 µm membrane challenge testing.
• Teaching laboratories: demonstration of vacuum filtration kinetics, pore size–flow rate relationships, and solvent degassing thermodynamics.

FAQ

Is the sintered glass frit replaceable?
Yes—the frit disc is a standardized 50 mm diameter component secured with a PTFE-faced retaining ring; replacement frits (G3/G4) are available as consumables.
Can this unit be used under positive pressure?
No—it is engineered exclusively for vacuum-assisted filtration; pressurization may compromise joint integrity and cause glass fracture.
What vacuum level is required for optimal degassing performance?
A stable vacuum of –0.095 MPa (≤10 mbar absolute) is recommended to achieve ≥85% dissolved gas reduction in 10–15 minutes for typical acetonitrile/water mixtures.
Does the assembly include a vacuum pump?
No—the DL-2000 is sold as a filtration manifold only; users must supply a chemically compatible vacuum source meeting flow and ultimate pressure specifications.
Are calibration certificates available for the volumetric flask?
Yes—optional ISO/IEC 17025-accredited calibration certificates (per ISO 1042) can be provided upon request, including uncertainty budgets at 20 °C.