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Cole-Parmer FH100M Single-Channel Precision Peristaltic Pump

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Origin USA
Manufacturer Type Authorized Distributor
Origin Category Imported
Model FH100M
Pricing Available Upon Request
Flow Rate 0.0012–160 mL/min
Speed Range 2–200 RPM
Reversible Yes
Flow Accuracy ±0.25% (with calibrated flow system)
Speed Resolution 0.1 RPM (4–400 RPM range)
Speed Regulation Accuracy ±0.25% of full scale
Input Control Signals 0–20 mA, 4–20 mA, or 0–10 VDC
Output Signals 4–20 mA or 0–10 VDC
Pulse Output 5 V TTL tachometer signal
Motor Type 1/10 HP (75 W) permanent magnet DC motor
Power Supply Auto-switching 115/230 VAC, 50/60 Hz
Operating Temperature 0–40 °C
Storage Temperature −25–65 °C
Enclosure Material ABS housing
filter media glass-filled nylon and polycarbonate
IP Rating IP31
Certifications ETL, cETL, CE, RoHS
Dimensions (L×W×H) 31.7 × 27.9 × 15.2 cm (12.5 × 11 × 6 in)
Net Weight 7 kg (15 lbs)

Overview

The Cole-Parmer FH100M is a single-channel, high-precision peristaltic pump engineered for demanding laboratory and process applications where fluid integrity, repeatability, and operational flexibility are critical. Based on the principle of positive displacement via roller compression of flexible tubing, the FH100M delivers non-invasive, contamination-free fluid handling—ideal for sensitive biological samples, reagents, cell cultures, and sterile processes. Its design eliminates valves, seals, and internal wetted surfaces beyond the tubing itself, enabling dry-run capability, self-priming, zero backflow, and complete fluid isolation. Unlike diaphragm or piston pumps, it imposes minimal shear stress, making it suitable for shear-sensitive suspensions, emulsions, foams, gas-liquid mixtures, and highly viscous media up to ~50,000 cP (depending on tubing selection and flow conditions). The pump operates across a wide dynamic range—from ultra-low flows (1.2 µL/min) to 160 mL/min—with fine speed resolution and tight speed regulation, supporting both continuous infusion and discrete dispensing protocols.

Key Features

  • True fluid isolation: Only the pump tubing contacts the sample—no wetted metal or elastomer components beyond the tube interior.
  • High metrological performance: Flow accuracy of ±0.25% when paired with calibrated tubing and verified flow systems (e.g., gravimetric or timed-volume validation per ISO 8599 or ASTM D1298).
  • Multi-mode control architecture: Supports manual knob operation, analog voltage/current input (0–10 V / 4–20 mA), digital I/O (direction, start/stop, pulse output), and optional RS-485 Modbus RTU for integration into SCADA or PLC-controlled environments.
  • Programmable dispensing modes: Configurable volume-based, time-based, or cycle-based delivery—including repeat dispensing, timed pauses, and bidirectional transfer sequences.
  • Robust mechanical construction: Pump head fabricated from corrosion-resistant materials including stainless steel, anodized aluminum, and Rulon® bearing surfaces; housing meets IP31 ingress protection for dust and vertically falling water droplets.
  • Low-maintenance operation: No lubrication, no valves, no seals—routine maintenance limited to periodic tubing replacement and visual inspection of rollers and housing alignment.
  • Global usability: On-screen interface supports seven languages (including English, Chinese, Spanish, French, German, Japanese, and Korean) with intuitive navigation and real-time parameter feedback.

Sample Compatibility & Compliance

The FH100M accommodates a broad spectrum of fluid types without modification: aqueous buffers, organic solvents (compatible with appropriate tubing such as PharMed® BPT or Tygon® S-50-HL), cell culture media, blood derivatives, fermentation broths, and two-phase systems. Tubing selection governs chemical compatibility, pressure rating, and particle shedding characteristics—users may choose from silicone, Viton®, EPDM, or fluoropolymer-lined options depending on application requirements. The device complies with key international safety and electromagnetic compatibility standards: ETL and cETL listing per UL 61010-1 (Laboratory Equipment), CE marking under the Low Voltage Directive (2014/35/EU) and EMC Directive (2014/30/EU), and RoHS 2011/65/EU compliance for hazardous substance restriction. While not intrinsically rated for Class I Div 1 environments, its electrical architecture supports integration into GMP-compliant workflows when deployed with audit-trail-capable software and documented calibration procedures aligned with ISO/IEC 17025 and FDA 21 CFR Part 11 expectations.

Software & Data Management

Although the FH100M operates autonomously via front-panel controls, its analog and digital I/O interfaces enable seamless integration with third-party data acquisition platforms (e.g., LabVIEW, MATLAB, or custom Python-based controllers) and industrial automation systems. The 5 V TTL tachometer output provides real-time rotational feedback for closed-loop speed verification, while 4–20 mA or 0–10 V analog outputs can be mapped to flow rate or motor load for trend logging. When connected to compliant supervisory software, the pump supports electronic recordkeeping of run parameters, start/stop timestamps, total dispensed volume, and error events—facilitating traceability in GLP and regulated QC environments. Firmware updates are performed via USB interface (optional accessory), ensuring long-term supportability and feature enhancement without hardware replacement.

Applications

The FH100M serves diverse roles across life science and industrial settings: continuous perfusion in bioreactors and organ-on-chip systems; precise reagent addition in automated ELISA or PCR setup stations; low-shear media transfer in stem cell expansion workflows; controlled nutrient dosing in algae photobioreactors; solvent delivery in HPLC gradient preparation; and gentle aspiration in microfluidic priming and vacuum-assisted filtration setups. Its ability to handle particulate-laden fluids and tolerate intermittent dry running also supports applications in environmental sampling, wastewater monitoring, and continuous pharmaceutical intermediate transfer where sterility assurance and material compatibility are paramount.

FAQ

What tubing sizes and materials are compatible with the FH100M?

Standard configurations support inner diameters from 0.1 mm to 4.8 mm, with validated compatibility for silicone, PharMed® BPT, Tygon® S-50-HL, Viton®, and Norprene® tubing—selection must align with fluid chemistry, pressure, and regulatory requirements.

Can the FH100M be integrated into a GMP-compliant manufacturing process?

Yes—when paired with documented calibration, change control procedures, and electronic logging via external software meeting 21 CFR Part 11 criteria (e.g., audit trail, electronic signatures, data integrity safeguards), it fulfills core instrumentation requirements for pharmaceutical and biotech production environments.

Is remote firmware update supported?

Firmware upgrades require connection to a host PC via USB using Cole-Parmer’s official configuration utility; updates preserve all user-defined presets and calibration offsets.

Does the pump include built-in flow calibration?

No—the FH100M is a speed-controlled peristaltic pump; volumetric accuracy depends on tubing geometry, elasticity, and drive speed. For certified flow delivery, users must perform gravimetric or volumetric calibration using traceable standards and document results per ISO/IEC 17025 guidelines.

What is the expected service life of the pump head and motor under continuous operation?

With proper tubing selection and routine maintenance (e.g., roller cleaning every 500 operating hours), the pump head maintains dimensional stability for >10,000 hours; the PMDC motor is rated for >20,000 hours MTBF at nominal load conditions.

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