Cole-Parmer Masterflex 75211-70 Digital Gear-Driven Peristaltic Pump with Remote Control Capability

Overview

The Cole-Parmer Masterflex 75211-70 is a precision-engineered, gear-driven digital peristaltic pump designed for laboratory and pilot-scale fluid handling applications requiring high repeatability, programmable operation, and seamless integration into automated systems. Utilizing positive displacement via occlusion of flexible tubing by rotating rollers—principally governed by the principles of peristalsis—the 75211-70 delivers pulse-free, contamination-free flow without internal valves or seals contacting the fluid path. Its digitally controlled brushless DC motor ensures stable rotational speed across the full 36–3600 rpm range, translating directly to precise volumetric delivery from 0.6 to 4212 mL/min when paired with standard Micropump® A-series pump heads. The drive unit is engineered for long-term stability under continuous operation and features a robust metal housing rated to IP33—providing protection against vertically falling water droplets and ingress of solid objects larger than 2.5 mm—making it suitable for shared lab environments where incidental splashes or dust exposure may occur.

Key Features

• Four programmable operating modes displayed on a backlit graphical LCD: Continuous Run, Timed Dispense, Repetitive Dispense, and Volume-Based Dispense—enabling real-time monitoring of elapsed time, dispensed volume, and current RPM.
• Integrated cumulative volume tracking across multiple dispensing cycles, supporting quantitative process documentation and material usage reconciliation.
• Stackable architecture allows up to three 75211-70 units to be physically mounted in vertical alignment, minimizing benchtop footprint while maintaining independent control and status visibility.
• Dedicated DB25 female remote interface port supports analog input for speed setpoint (0–20 mA, 4–20 mA, or 0–10 V), direction control, start/stop, and wash commands via open-collector or dry-contact signals.
• Programmable inter-cycle delay intervals eliminate manual intervention during sequential dispensing protocols—critical for unattended batch processing or multi-step reagent addition workflows.
• Front-panel multilingual interface (English, Spanish, French, German) and optional footswitch (Cat. No. 07523-92, 1.8 m cable) support ergonomic, hands-free operation in glove-compatible or sterility-sensitive settings.

Sample Compatibility & Compliance

The 75211-70 is compatible exclusively with Micropump® A-series quick-connect pump heads—ensuring consistent tubing compression geometry and eliminating calibration drift associated with manual head adjustment. Tubing selection remains fully user-determined (e.g., PharMed® BPT, Norprene®, Viton®), allowing chemical compatibility optimization per application. While the drive unit itself carries no intrinsic regulatory certification, its design aligns with general requirements for laboratory instrumentation under ISO/IEC 17025-accredited quality systems. When integrated into GxP environments, the analog remote I/O enables connection to PLCs or SCADA systems that maintain audit trails compliant with FDA 21 CFR Part 11 (when paired with validated software layers). The absence of fluid-path wetted parts beyond tubing supports cleaning validation per ASTM E3019 and simplifies changeover between incompatible solvents or biological media.

Software & Data Management

The 75211-70 operates as a standalone instrument with no embedded firmware-based data logging; however, its analog I/O architecture facilitates direct integration with third-party data acquisition platforms (e.g., LabVIEW, MATLAB, or industrial PLCs) for time-synchronized parameter capture—including actual speed feedback (0–20 mA tachometer output), run status, and cumulative volume counters. All front-panel settings are retained through power cycling. For traceability-critical applications, users may implement external timestamped logging of analog control signals and discrete outputs—supporting GLP/GMP-aligned record retention when combined with appropriate electronic notebook or LIMS infrastructure. Optional accessories include DB25 male mating connector (Cat. No. 07523-94) for custom cable assembly and DIN-rail mounting kits for fixed-installation configurations.

Applications

• Automated reagent dispensing in clinical chemistry analyzers and ELISA workflow stations
• Controlled nutrient or inhibitor delivery in bioreactor feed systems and perfusion culture platforms
• Continuous sampling loops for online HPLC or IC autosamplers requiring low-pulse, chemically inert transport
• Calibration standard delivery in environmental testing labs (e.g., EPA Method 200.8, ISO 11843)
• Low-flow solvent transfer in analytical sample preparation—particularly where metallic pump components must be avoided
• Integration into ISO 13485-certified medical device manufacturing lines for non-sterile fluid routing

FAQ

What pump heads are compatible with the 75211-70 drive unit?
Only Micropump® A-series quick-connect pump heads (e.g., 07518-10, 07518-20) are mechanically and electronically compatible. Other head types—including L/S or I/P series—will not mount or function correctly.
Does the 75211-70 support digital communication protocols such as RS-232 or Modbus?
No. This model provides analog I/O only (voltage/current signals) via its DB25 interface. Digital protocol support requires upgrade to the Masterflex I/P Series Smart Drivers or integration via external signal converters.
Can the cumulative volume counter be reset remotely?
Reset is front-panel only—accessible via the LCD menu. There is no dedicated remote command line or analog signal assigned to volume counter reset.
Is the power supply auto-ranging for global voltage inputs?
Yes. The unit accepts 90–260 VAC at 50/60 Hz without manual configuration or voltage selector switches.
What is the maximum recommended tubing inner diameter for use with A-series pump heads on this drive?
Tubing ID up to 3.2 mm (1/8″) is supported with standard A-series heads. Larger IDs require verification of occlusion integrity and flow linearity per ASTM D3418.