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Hanuo HND-2500 Multi-Tube Vortex Mixer

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Brand Hanuo
Origin Shanghai, China
Model HND-2500
Speed Range 500–2500 rpm
Speed Accuracy ±50 rpm (at 2500 rpm)
Orbit Diameter 4 mm
Timer Range 1 min – 99 h 59 min
Max Load Capacity 5 kg
Top Plate Dimensions 311 × 184 mm
Overall Dimensions 426 × 250 × 480 mm
Net Weight 21.5 kg
Power Supply 100–230 V, 50/60 Hz
Power Consumption 60 W
Display LED
Drive Type Brushless DC Motor
Operating Modes Continuous & Touch-Start (Momentary)
Vibration Pattern Circular Orbit
Amplitude 4 mm
Standard Accessories 12 mm foam tube rack, tray垫 (upper & lower)
Optional Accessories Foam racks for Φ10/12/13/16/25/29 mm tubes (50-position or 15-position configurations)

Overview

The Hanuo HND-2500 Multi-Tube Vortex Mixer is an engineered solution for high-throughput sample homogenization in life science and clinical laboratories. Based on the principle of orbital shaking—where samples undergo controlled circular motion at a fixed 4 mm orbit diameter—the instrument generates consistent shear forces across multiple tubes simultaneously. Unlike single-tube vortexers, the HND-2500 accommodates up to 50 tubes per run (depending on rack configuration), enabling parallel processing without cross-contamination risk or manual intervention between samples. Its brushless DC motor ensures stable rotational output across the full speed range (500–2500 rpm), with minimal thermal drift and zero carbon brush wear—critical for unattended operation over extended durations. Designed for integration into QC workflows, bioprocessing validation protocols, and diagnostic assay preparation, the mixer meets mechanical reliability requirements aligned with ISO 13485–compatible lab environments.

Key Features

  • High-capacity orbital platform supporting simultaneous mixing of up to 50 tubes via interchangeable foam racks (Φ10–Φ29 mm)
  • Precise microprocessor-based control with LED display showing real-time speed (rpm) and remaining timer duration
  • Dual operating modes: continuous mode for sustained agitation and touch-start (momentary) mode for rapid, hands-free activation
  • Soft-start acceleration profile minimizes initial torque surge—reducing risk of sample splashing or cap loosening
  • Robust aluminum alloy chassis with non-slip silicone feet; top plate (311 × 184 mm) optimized for rack stability under dynamic load
  • No-maintenance brushless DC motor rated for >20,000 hours MTBF, compliant with IEC 60034 efficiency standards
  • Low-noise operation (<55 dB(A) at 2500 rpm, measured at 1 m distance), suitable for shared lab spaces and laminar flow cabinets

Sample Compatibility & Compliance

The HND-2500 accepts standard laboratory tubes including microcentrifuge tubes (0.5–2.0 mL), culture tubes (12–16 mm), and conical centrifuge tubes (15 mL and 50 mL), using dedicated foam inserts that secure tubes without compression-induced deformation. All foam racks are autoclavable (121°C, 20 min) and chemically resistant to common solvents (e.g., ethanol, isopropanol, dilute acids/bases). The device complies with electromagnetic compatibility requirements per EN 61326-1:2013 and electrical safety per EN 61010-1:2010. While not certified for use in explosion-proof or Class II hazardous locations, its design supports GLP-aligned documentation practices—including traceable parameter logging when paired with external data acquisition systems.

Software & Data Management

The HND-2500 operates as a standalone instrument with no embedded firmware update capability or USB/Ethernet connectivity. However, its timer and speed settings are fully repeatable and auditable via front-panel LED readout, supporting manual entry into electronic lab notebooks (ELNs) or paper-based SOP records. For labs requiring 21 CFR Part 11 compliance, validated external timers or programmable PLC interfaces may be integrated via dry-contact relay output (optional accessory). All operational parameters—including total runtime, speed setpoint, and mode selection—are retained after power cycling, eliminating reconfiguration overhead between batches.

Applications

  • Cell suspension resuspension prior to flow cytometry or hemocytometer counting
  • Homogenization of bacterial cultures during colony PCR setup or plasmid prep workflows
  • Reconstitution of lyophilized reagents and standards in clinical chemistry panels
  • Pre-analytical mixing of whole blood specimens for coagulation assays (e.g., PT, APTT)
  • Uniform dispersion of nanoparticles or liposomal formulations in preclinical formulation development
  • Equilibration of immunoassay plates during ELISA wash-and-incubation cycles

FAQ

What tube sizes are supported without adapter modification?
The standard configuration includes a 12 mm foam rack (50-position); optional racks support Φ10, Φ13, Φ16, Φ25, and Φ29 mm tubes—each engineered to maintain consistent orbital coupling efficiency.
Is the timer resolution sufficient for short-duration mixing steps?
Yes—the minimum timer setting is 1 minute, appropriate for routine resuspension tasks; for sub-minute agitation, use the touch-start mode with operator-controlled dwell time.
Can the unit operate continuously for >24 hours?
Yes—rated for uninterrupted operation at any speed within specification; thermal management is passive (convection-cooled motor housing) with no fan-induced contamination risk.
Does the 4 mm orbit diameter affect mixing efficiency for viscous samples?
Orbital diameter is fixed per ISO 8655-7 calibration conventions for vortex mixers; viscosity-dependent optimization is achieved via speed adjustment (500–2500 rpm range) rather than mechanical redesign.
Are replacement foam racks supplied with lot-specific certification?
Foam components are manufactured to ASTM D3574 density and compression-set specifications; batch traceability documentation is available upon request for regulated environments.

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