Herexi TD5-1 Benchtop Filtration Centrifuge

Overview

The Herexi TD5-1 Benchtop Filtration Centrifuge is an engineered solution for solid–liquid separation tasks requiring simultaneous filtration, washing, dewatering, and concentration in a single operational cycle. Unlike conventional sedimentation centrifuges, the TD5-1 employs a perforated basket rotor combined with controlled rotational dynamics to generate centrifugal force-driven fluid passage through filter media—enabling true filtration-based separation under dynamic mechanical stress. Designed for low-speed operation (up to 4000 rpm, delivering 2200 ×g), it targets applications where thermal sensitivity, particle integrity, or post-separation dryness (>90% moisture removal) are critical. Its architecture conforms to fundamental principles of centrifugal filtration as defined in ISO 15879 and ASTM D1141, supporting reproducible process development in regulated laboratory environments.

Key Features

• Integrated multi-function operation: Combines filtration, cake washing, mechanical dewatering, and slurry concentration within one rotor cycle—reducing handling steps and cross-contamination risk.
• TFT true-color touchscreen interface with real-time dual-parameter display: Simultaneously shows set values (speed, time, acceleration/deceleration profiles) and live operational feedback (actual rpm, elapsed time, RCF, lid status).
• Programmable timer with extended range (0–99 h 59 min): Supports long-duration batch processing for crystallization recovery, biomass harvesting, or slow-settling suspensions.
• Active vibration damping system with auto-balancing mechanism: Compensates for load asymmetry during acceleration and deceleration, maintaining stability across variable fill conditions (100–1000 mL).
• Motorized interlocked lid lock: Ensures full mechanical and electrical interlock compliance; rotation prohibited unless lid is fully closed and sealed—meeting IEC 61010-1 safety requirements for laboratory equipment.
• Full stainless steel chamber and basket assembly (AISI 304): Provides corrosion resistance against organic solvents, saline solutions, weak acids/bases, and biological buffers—validated per ASTM A240 and ISO 9223 C3 classification.
• Low acoustic signature (≤65 dB[A] at 1 m): Achieved via optimized motor mounting, balanced rotor dynamics, and acoustic insulation—suitable for shared lab spaces without dedicated isolation rooms.

Sample Compatibility & Compliance

The TD5-1 accommodates standard conical or flat-bottom filtration baskets compatible with common filter media—including polypropylene mesh (10–150 µm), cellulose acetate membranes, and sintered stainless steel discs. It supports aqueous, alcoholic, and mildly corrosive suspensions typical in pharmaceutical granulation studies (USP ), bioprocess harvest clarification (ISO 22442-1), and environmental sludge dewatering (EPA Method 1680). All electrical components comply with CE marking directives (2014/30/EU EMC, 2014/35/EU LVD), while mechanical design adheres to EN 61010-1:2010 + A1:2019 for laboratory safety. The device is suitable for GLP-compliant workflows when paired with audit-trail-capable external logging systems.

Software & Data Management

While the TD5-1 operates as a standalone instrument with embedded firmware, its touchscreen controller logs all executed runs—including date/time stamp, parameter setpoints, actual runtime, final rpm, and lid open/close events—in non-volatile memory (retention ≥10 years). Data export is supported via USB 2.0 port (FAT32 formatted drive), generating CSV-formatted records compatible with LIMS integration or statistical process control (SPC) platforms. Optional RS-485 serial interface enables remote monitoring and parameter synchronization in networked lab infrastructures compliant with IEEE 802.3 Ethernet standards.

Applications

• Pharmaceutical: Isolation of crystalline APIs after antisolvent precipitation; washing of wet filter cakes prior to drying; recovery of monoclonal antibody aggregates from clarified harvests.
• Biotechnology: Harvesting microbial cells (E. coli, yeast) and mammalian cell lines (CHO, HEK293); dewatering of lysates prior to chromatography loading.
• Environmental Testing: Solid-phase extraction of suspended solids from wastewater effluents; preparation of sediment samples for heavy metal analysis (EPA 6010D).
• Food & Beverage: Clarification of fruit juice concentrates; separation of starch granules from potato or corn slurries; yeast removal in beer fermentation broths.
• Academic Research: Teaching centrifugal filtration kinetics; comparative evaluation of filter aid performance; scale-down modeling for industrial basket centrifuge validation.

FAQ

What types of rotors are compatible with the TD5-1?
The TD5-1 accepts only Herexi-certified perforated basket rotors (e.g., HB-1000F, HB-500F) designed for filtration duty. Angle rotors or swinging-bucket configurations are not supported due to structural and safety constraints.
Can the TD5-1 be used for sterile processing?
The unit itself is not classified as aseptic equipment; however, its stainless steel chamber and removable basket allow for autoclaving (121°C, 20 min, gravity cycle) between runs when validated per ISO 17665-1.
Is speed calibration traceable to national standards?
Yes—factory calibration uses NIST-traceable tachometer references (±0.5% accuracy), with documentation provided per ISO/IEC 17025 requirements upon request.
Does the TD5-1 support variable acceleration/deceleration profiles?
It offers three preset ramp modes (fast/standard/slow) but does not support user-defined gradient programming; deceleration is always passive (coast-to-stop) to preserve filter cake structure.
What maintenance intervals are recommended?
Lubrication-free brushless DC motor requires no scheduled maintenance; annual verification of lid interlock function, vibration dampers, and touchscreen responsiveness is advised per manufacturer’s service manual (Rev. 3.2, 2023).