HL-5B Single-Channel High-Flow Peristaltic Pump

Overview

The HL-5B Single-Channel High-Flow Peristaltic Pump is a microprocessor-controlled peristaltic pump engineered for continuous, pulse-free fluid delivery in laboratory, pilot-scale, and light industrial applications. Based on the principle of positive displacement via roller compression of flexible tubing, it delivers precise volumetric flow without internal valves or seals—ensuring contamination-free operation and eliminating cross-sample carryover. Unlike centrifugal or diaphragm pumps, the HL-5B maintains consistent flow across varying fluid viscosities and back pressures up to 0.2 MPa, making it suitable for media transfer, buffer circulation, fermentation feed control, and inline filtration support. Its robust mechanical architecture and wide speed regulation range enable stable performance under extended duty cycles, while the digital rpm display provides real-time operational feedback aligned with ISO 8573-1 and ASTM D341 viscosity correlation standards.

Key Features

• Microprocessor-based speed control with non-volatile memory for parameter retention after power cycling
• Wide adjustable speed range supporting flow rates from 200 to 100,000 mL/h (dependent on tubing ID and fluid properties)
• Digital LED display showing actual rotational speed (rpm), enabling traceable calibration verification
• Single-channel design optimized for high-throughput applications requiring dedicated flow paths
• Modular roller head assembly compatible with standard peristaltic tubing sizes (e.g., PharMed® BPT, Tygon® LFL, and silicone formulations)
• Thermally stable housing and low-noise motor drive compliant with IEC 61000-6-3 EMC emission limits
• Front-panel start/stop, direction reversal, and speed adjustment buttons for intuitive manual operation

Sample Compatibility & Compliance

The HL-5B accommodates a broad spectrum of aqueous, mildly corrosive, and shear-sensitive fluids—including cell culture media, enzyme solutions, polymer emulsions, and buffered saline—provided appropriate tubing material is selected per chemical compatibility charts (e.g., Cole-Parmer Chemical Resistance Guide). It supports tubing inner diameters from 1.6 mm to 9.5 mm, allowing flow optimization across viscosity ranges up to ~5,000 cP. While not certified for Class I Div 1 hazardous locations, the unit meets CE marking requirements for electromagnetic compatibility and low-voltage safety (EN 61326-1, EN 61000-6-2/6-3). For regulated environments, its repeatable speed control and data retention capability facilitate alignment with GLP documentation practices; however, native audit trail or 21 CFR Part 11 electronic signature functionality is not embedded and must be implemented at the system integration level.

Software & Data Management

The HL-5B operates as a standalone instrument with no built-in USB, RS-232, or Ethernet interface. All configuration and operation are managed locally via front-panel controls. For integration into automated workflows, optional analog (0–5 V or 4–20 mA) or digital (TTL-level) external control inputs can be configured through third-party signal conditioning modules. Users implementing LIMS or SCADA systems may log operational parameters—including runtime, cumulative volume estimates (calculated from rpm × tubing displacement factor), and status flags—using external data acquisition hardware. Calibration records and maintenance logs should be maintained manually or via institutional electronic quality management systems (eQMS) to satisfy ISO/IEC 17025 Clause 7.7 traceability requirements.

Applications

• Continuous feeding of bioreactors and chemostats in microbial and mammalian cell culture processes
• Recirculation of cleaning-in-place (CIP) solutions during equipment sanitization validation
• Delivery of mobile phases in preparative chromatography and column regeneration protocols
• Controlled dosing of coagulants or flocculants in water treatment pilot studies
• Media perfusion in organ-on-chip and microfluidic platform development
• High-volume buffer exchange in tangential flow filtration (TFF) setups

FAQ

What tubing sizes are recommended for maximum flow rate performance?
For rated flow up to 100,000 mL/h, use tubing with an inner diameter of 6.4–9.5 mm (e.g., Norprene® A-60-F or Masterflex® I/P 17). Flow accuracy degrades above 80% of theoretical maximum due to pulsation amplitude and roller slippage.
Can the HL-5B maintain constant flow under variable back pressure?
Yes—within its specified pressure limit of ≥0.2 MPa, flow deviation remains ≤±3% across pressure changes from 0.05 to 0.2 MPa when operated at fixed rpm and with properly tensioned tubing.
Is firmware upgrade supported?
No—the HL-5B uses fixed-function embedded logic; no field-upgradable firmware or user-accessible configuration files are provided.
Does it comply with FDA or USP standards?
The pump itself is not USP or certified, but its tubing-contacting components may be validated for use in pharmaceutical manufacturing if assembled with USP Class VI-compliant tubing and subjected to facility-specific IQ/OQ protocols.
What is the expected service life of the drive motor?
Under continuous operation at ≤70% of maximum rated speed and ambient temperatures below 35°C, the brushless DC motor is rated for ≥15,000 hours of service life per manufacturer specifications.