Jiapeng BSZ-100 LCD Display Automatic Fraction Collector

Overview

The Jiapeng BSZ-100 LCD Display Automatic Fraction Collector is a precision-engineered time-based liquid-phase fraction collector designed for integration into medium- and low-pressure chromatography systems. It operates on the principle of programmable time-triggered tube switching, enabling reproducible, unattended collection of eluent fractions during column chromatography, gel filtration, ion exchange, or affinity purification workflows. Unlike flow-triggered or UV-signal-activated collectors, the BSZ-100 prioritizes temporal consistency—making it especially suitable for gradient elution protocols where retention time stability is critical, or when paired with peristaltic or piston-driven constant-flow pumps lacking analog output signals. Its microprocessor-controlled architecture ensures high timing accuracy across extended runs, while the sealed ABS housing and sloped 35° control panel support ergonomic operation in regulated laboratory environments.

Key Features

• Microcontroller-based timing engine with ±0.1% timing accuracy over full range (1 second to 199 hours, 59 minutes, 59 seconds)
• Circular, digitally numbered tube tray accommodating 100 × 12 mL standard test tubes—each position labeled with a permanent, laser-etched numeral for unambiguous sample identification and retrieval
• Large-format blue-membrane Chinese-language LCD display with intuitive menu navigation and real-time parameter feedback (remaining time, current tube index, active mode)
• Non-volatile memory retains all user-defined settings—including start/stop times, tube count, and trigger configuration—for up to 10 years following power interruption
• Dual-directional timer operation: supports both forward-counting (elapsed time) and reverse-counting (countdown to next switch) modes
• COM serial interface enables hardware-level synchronization with compatible peristaltic or syringe pumps (e.g., Jiapeng BT100-2J, HL-2S), allowing external initiation of collection cycles without manual intervention
• Keebio solenoid-driven fluid shut-off valve ensures leak-free tube transitions and minimizes cross-contamination between fractions
• Modular tray design permits interchangeability with other BSZ-series trays (e.g., BSZ-160) without recalibration; no positional alignment required

Sample Compatibility & Compliance

The BSZ-100 is compatible with standard 12 mL round-bottom or conical centrifuge tubes (16 × 100 mm or 16 × 110 mm dimensions). Optional solvent-resistant tube trays—constructed from chemically inert polypropylene—are available for use with organic mobile phases including acetonitrile, methanol, chloroform, and ethyl acetate. While the device itself does not carry CE, UL, or FDA 510(k) certification, its electrical design conforms to IEC 61010-1 safety standards for laboratory equipment. The non-volatile memory system satisfies basic GLP documentation requirements for audit trail integrity, and the deterministic time-based collection logic supports method reproducibility under ISO/IEC 17025-accredited testing laboratories when validated alongside upstream chromatographic instrumentation.

Software & Data Management

The BSZ-100 operates as a standalone hardware controller without proprietary PC software. All configuration is performed locally via the front-panel LCD interface using a hierarchical menu system with contextual help prompts. Parameter logs—including collection start time, total elapsed duration, tube index sequence, and power-loss timestamps—are stored in EEPROM and can be reviewed directly on-screen. For laboratories requiring electronic recordkeeping, the COM port supports ASCII command protocol (RS-232 level), enabling integration with custom LabVIEW, Python, or MATLAB scripts for automated log export, timestamp synchronization with HPLC data systems, or CSV-formatted run reports. No cloud connectivity or remote access functionality is implemented, preserving data sovereignty in compliance-sensitive environments.

Applications

• Preparative SEC (Size Exclusion Chromatography) of proteins and polymers, where consistent fraction volume per time interval ensures accurate molecular weight distribution profiling
• Desalting and buffer exchange steps in protein purification workflows prior to lyophilization or analytical characterization
• Fractionation of natural product extracts (e.g., plant alkaloids, flavonoids) under isocratic conditions with post-run TLC or LC-MS analysis
• Quality control sampling in small-scale bioprocessing, including harvest clarification and intermediate pool collection
• Educational chromatography labs—its tactile interface and visual feedback simplify student training in separation fundamentals without dependency on computer interfaces

FAQ

Does the BSZ-100 support flow-rate–triggered collection?
No. It is exclusively time-programmable. Flow-triggered collection requires an external flow sensor and signal converter not included with this model.
Can I use non-standard tube sizes?
Yes—provided tube outer diameter fits within the tray’s 18 mm bore tolerance and height remains ≤115 mm. Adapters are not supplied but may be fabricated in-house.
Is the COM port compatible with modern USB-to-serial adapters?
Yes, when configured for TTL/RS-232 level translation at 9600 baud, 8N1. Driver installation is required on Windows/macOS/Linux.
What maintenance is required for long-term reliability?
Annual inspection of valve actuation force and tube tray rotation smoothness is recommended. No lubrication or calibration is needed under normal operating conditions.
How is data integrity ensured during extended unattended runs?
All timing parameters and operational states are written to write-protected EEPROM sectors upon each mode change or power cycle—no volatile RAM dependency exists.