METTLER TOLEDO ME204 Analytical Balance
| Brand | METTLER TOLEDO |
|---|---|
| Origin | Shanghai, China |
| Model | ME204 |
| Instrument Type | Analytical Balance |
| Maximum Capacity | 220 g |
| Readability | 0.1 mg |
| Repeatability | 0.1 mg |
| Linearity | ±0.2 mg |
| Calibration | Internal |
| Pan Size | 90 mm diameter |
| Draft Shield Height | 220 mm |
| Dimensions (W×D×H) | 210 × 344 × 344 mm |
| Construction | Die-cast metal base with reinforced housing |
Overview
The METTLER TOLEDO ME204 Analytical Balance is a high-precision mass measurement instrument engineered for routine laboratory applications requiring consistent 0.1 mg readability and traceable accuracy. Based on electromagnetic force compensation (EMFC) technology, the ME204 delivers stable, drift-compensated measurements under variable environmental conditions—including minor air currents, temperature fluctuations, and vibration—common in shared lab spaces. Its design integrates METTLER TOLEDO’s proprietary monolithic sensor architecture, which minimizes mechanical hysteresis and ensures long-term stability of calibration parameters. The balance operates within ISO/IEC 17025-compliant environments and supports GLP/GMP documentation workflows through built-in audit trail functionality when connected to LabX software (optional). With a maximum capacity of 220 g and optimized thermal mass distribution, the ME204 achieves rapid stabilization times (<2 s typical), enabling efficient throughput in QC, R&D, and teaching laboratories.
Key Features
- Internal calibration system with one-touch activation—no external weights required; complies with ASTM E898 and USP <41> requirements for routine performance verification.
- Ergonomic front-access design with intuitive keypad layout and large, high-contrast LCD display (128 × 64 pixels) for glove-compatible operation.
- Durable die-cast metal base and reinforced polymer housing provide mechanical robustness against accidental impact and daily wear.
- Integrated level indicator and front-mounted adjustable leveling feet ensure rapid, repeatable setup without tools.
- Removable draft shield with 220 mm effective height and smooth-sliding side doors facilitate handling of tall or irregularly shaped samples while maintaining measurement integrity.
- Stainless steel weighing pan (90 mm Ø) resists corrosion and simplifies cleaning—compatible with common laboratory disinfectants per ISO 15190 Annex B guidelines.
Sample Compatibility & Compliance
The ME204 accommodates a broad range of sample types—from powders and granules to small solid components and pre-weighed vials—within its 220 g capacity limit. Its low-profile pan geometry and shield clearance support use with standard 50 mL centrifuge tubes, volumetric flasks, and crucibles. The balance meets international regulatory expectations for analytical instrumentation: it is CE-marked per EU Directive 2014/30/EU (EMC) and 2014/32/EU (Measuring Instruments Directive); its internal calibration algorithm is validated against OIML R 76-1 Class I tolerances. For regulated environments, optional RS232/USB interfaces enable direct integration into LIMS or electronic lab notebooks (ELN), supporting 21 CFR Part 11 compliance when paired with METTLER TOLEDO LabX software.
Software & Data Management
While the ME204 operates as a standalone instrument, its serial and USB ports support seamless data export to spreadsheets or quality management systems. When interfaced with METTLER TOLEDO LabX software (sold separately), users gain full audit trail capability—including user login tracking, parameter change logs, and timestamped result export—with configurable electronic signatures. All measurement data can be automatically annotated with metadata (e.g., operator ID, sample ID, balance ID, environmental conditions if external sensors are connected). Built-in memory stores up to 999 results locally, with overwrite protection enabled by default to prevent accidental deletion.
Applications
- Quantitative preparation of standards and reference materials in pharmaceutical assay development (aligned with ICH Q5C and USP <1251>).
- Weighing of active pharmaceutical ingredients (APIs) during formulation studies where ±0.1 mg tolerance is mandated.
- Gravimetric analysis in environmental testing labs (e.g., TSS, ash content, filter residue determination per EPA Method 160.1).
- Student laboratory instruction in chemistry and materials science, where reproducibility and ease of use are pedagogical priorities.
- Quality control of incoming raw materials in food, cosmetics, and fine chemical manufacturing per ISO 22000 clause 8.3.2.
FAQ
What is the difference between repeatability and linearity in analytical balances?
Repeatability (0.1 mg for the ME204) refers to the standard deviation of multiple consecutive weighings of the same load under identical conditions. Linearity (±0.2 mg) quantifies the maximum deviation from the ideal straight-line relationship between applied mass and displayed value across the full range.
Does the ME204 require external calibration weights?
No—the integrated internal calibration mechanism uses a motor-driven precision weight actuator, eliminating dependency on external masses and reducing risk of contamination or misplacement.
Can the ME204 be used in a fume hood?
It is not recommended due to airflow-induced instability; however, if necessary, installation must include full draft shield engagement and thermal equilibration for ≥30 minutes prior to use.
Is the ME204 compliant with ISO/IEC 17025 accreditation requirements?
Yes—when operated according to METTLER TOLEDO’s documented procedures and maintained with scheduled verification using traceable standards, the ME204 satisfies clause 6.4.10 (Equipment Verification) and 6.5.2 (Measurement Traceability) of ISO/IEC 17025:2017.
