OHAUS VXMNDG Mini Vortex Mixer

Overview

The OHAUS VXMNDG Mini Vortex Mixer is a compact, digitally controlled laboratory instrument engineered for precise, reproducible mixing of small-volume liquid samples in life science, clinical diagnostics, and pharmaceutical research environments. Utilizing orbital shaking at variable speeds—based on the principle of eccentric rotation—the device generates consistent vortexing action through a 4.9 mm orbit diameter, enabling efficient resuspension of pellets, homogenization of reagents, and thorough mixing of viscous or heterogeneous solutions. Unlike analog vortexers reliant on mechanical feedback alone, the VXMNDG integrates a microprocessor-based control system that actively monitors and maintains rotational speed within ±5 rpm of the setpoint across load variations, ensuring high inter-run repeatability critical for assay standardization and regulatory compliance.

Key Features

• Dual-parameter LED display showing real-time speed (rpm) and remaining timer duration (min), allowing operators to monitor both parameters simultaneously without interrupting operation.
• Digitally regulated motor drive delivering stable speed output from 500 to 2500 rpm, optimized for applications ranging from gentle resuspension of cell pellets to vigorous emulsification of immiscible phases.
• Single-platform design featuring a 7.6 cm flat surface with integrated conical cup adapter for secure placement of test tubes, culture tubes, and small flasks; compatible with optional stainless-steel 12-position microtube rack (sold separately).
• Non-continuous (momentary or timed) operation mode supports both hands-free timed runs (1–999 min) and instant activation via touch-sensitive start button—ideal for workflows requiring intermittent mixing steps.
• Robust all-metal housing and thermally stable internal architecture enable reliable performance across ambient lab conditions (4°C–40°C, 20–85% RH non-condensing), meeting long-term durability requirements in shared core facilities.
• Compliance-ready electrical design certified to CE and TÜV safety standards, supporting integration into GLP- and GMP-aligned laboratories where documented instrument qualification is required.

Sample Compatibility & Compliance

The VXMNDG accommodates a broad range of common labware including 0.2–50 mL conical tubes, 13–18 mm round-bottom test tubes, microcentrifuge tubes (with accessory rack), and small-volume glass or plastic vials. Its low-profile footprint and absence of refrigeration or heating elements make it suitable for use inside cold rooms, biosafety cabinets, and laminar flow hoods—provided ambient humidity remains below condensation thresholds. While not an ISO/IEC 17025-accredited instrument per se, its digital speed stability and traceable timer functionality support adherence to ASTM E2916-22 (Standard Guide for Validation of Laboratory Instruments) and facilitate inclusion in equipment qualification protocols (IQ/OQ/PQ) under FDA 21 CFR Part 11-compliant data management systems when paired with validated software interfaces.

Software & Data Management

The VXMNDG operates as a standalone benchtop device with no embedded firmware update capability or network connectivity. All operational parameters—including speed setpoint, timer value, and run status—are retained locally on the microprocessor during power cycling. For laboratories implementing electronic lab notebooks (ELNs) or LIMS integration, manual entry of mixing parameters remains standard practice; however, the device’s deterministic behavior (e.g., fixed ramp-up time, repeatable speed fidelity) enables robust correlation between instrument settings and downstream analytical outcomes—supporting auditability in regulated QC/QA environments. Optional calibration certificates (traceable to NIST standards) may be requested from OHAUS for periodic verification of speed accuracy.

Applications

• Resuspension of lyophilized reagents, bacterial pellets, and precipitated nucleic acids prior to downstream analysis.
• Preparation of homogeneous dilution series and calibration standards for ELISA, PCR, and spectrophotometric assays.
• Mixing of immiscible phases during solvent extraction protocols (e.g., phenol-chloroform DNA isolation).
• Homogenization of protein samples in RIPA or SDS lysis buffers prior to electrophoresis or mass spectrometry workflows.
• Blending of viscous formulations in early-stage biopharmaceutical development, including antibody-drug conjugate intermediates.
• Quality control testing of excipient compatibility in generic drug product development per USP <1058> guidance.

FAQ

Is the VXMNDG suitable for use with microcentrifuge tubes?
Yes—when equipped with the optional stainless-steel 12-tube rack, the VXMNDG provides secure, balanced mixing of 0.5–2.0 mL microcentrifuge tubes. The standard platform also supports single-tube vortexing using the included conical cup adapter.
Does the device offer programmable multi-step protocols?
No—the VXMNDG supports only single-parameter timed runs (speed + duration). Complex sequential mixing protocols require external scheduling via lab automation controllers or manual operator intervention.
Can the unit be operated continuously for extended periods?
It is designed for non-continuous, duty-cycle operation. Continuous runtime exceeding 30 minutes at maximum speed (2500 rpm) is not recommended due to thermal accumulation in the motor assembly; periodic rest intervals ensure optimal longevity and speed stability.
What maintenance is required?
Routine cleaning of the platform surface and conical cup with 70% ethanol is sufficient. No lubrication or internal servicing is required during normal operation. Annual verification of speed accuracy using a calibrated tachometer is advised for regulated applications.
Is a calibration certificate available?
OHAUS offers optional factory-issued calibration certificates (NIST-traceable) upon request at time of purchase or during scheduled service visits. These documents include measured speed deviation, timer accuracy, and environmental operating validation data.