PEAK Infinity XE 60 Membrane-Based Nitrogen Generator for Multi-Station LC-MS Supply
| Brand | PEAK |
|---|---|
| Origin | United Kingdom |
| Manufacturer Type | Original Equipment Manufacturer (OEM) |
| Import Category | Imported |
| Model | Infinity XE 60 |
| Nitrogen Generation Principle | Hollow-Fiber Membrane Separation |
| Maximum Nitrogen Flow Rate | 428 L/min |
| Output Pressure | 135 PSI (9.3 bar) |
| Nitrogen Purity | Up to 99.5% |
| Dew Point | −50°C |
| Air Inlet Requirement | ISO 8573-1:2010 Class 1.4.1 Compressed Air |
| Noise Level | <45 dB(A) |
| Warranty | 12 Months Comprehensive |
Overview
The PEAK Infinity XE 60 is a high-capacity, membrane-based nitrogen generator engineered for continuous, on-demand supply of laboratory-grade nitrogen gas to multiple analytical instruments—most notably liquid chromatography–mass spectrometry (LC-MS) systems operating in parallel. Utilizing proprietary hollow-fiber membrane separation technology, the XE 60 selectively permeates oxygen, water vapor, and other trace gases from clean, dry compressed air, retaining nitrogen with consistent purity and flow stability. Unlike pressure swing adsorption (PSA) systems, membrane generators offer inherently silent operation, zero moving parts within the separation module, and immunity to carbon molecular sieve degradation or valve cycling fatigue. The XE 60 is designed exclusively for integration into laboratories already equipped with a centralized, ISO-compliant compressed air infrastructure—eliminating the need for an integrated compressor and reducing footprint, heat load, and maintenance overhead.
Key Features
- Scalable nitrogen output: Adjustable flow range from 10 to 428 L/min at 135 PSI—field-upgradable without hardware replacement
- Multi-purity configuration: Selectable nitrogen purity levels between 95.0% and 99.5%, optimized for applications including ELSD, NMR solvent purging, FTMS ion source gas, sample evaporation, and electrospray ionization (ESI) in LC-MS
- IMM (Intelligent Modulation Management) technology: Dynamically matches compressed air consumption to real-time nitrogen demand, reducing average compressor runtime by up to 35% and extending service intervals for upstream air treatment components
- Zero internal compression: No built-in air compressor—ensures silent operation (<45 dB[A]) and eliminates vibration transmission critical for sensitive mass spectrometers
- Compact footprint and modular design: Fits under standard lab benches or within utility alcoves; supports wall-mounting and rack-integrated deployment
- Compliance-ready architecture: Designed to support GLP/GMP workflows with optional audit-trail logging, digital I/O for building management systems (BMS), and compatibility with FDA 21 CFR Part 11–compliant software platforms
Sample Compatibility & Compliance
The Infinity XE 60 delivers nitrogen meeting ASTM D6352–22 specifications for instrumental gas purity and ISO 8573-1:2010 Class 1.4.1 inlet air requirements—ensuring compatibility with high-resolution LC-MS platforms from Thermo Fisher, Waters, Agilent, and Shimadzu. Its −50°C dew point output satisfies stringent moisture limits for ESI and APCI sources, minimizing adduct formation and signal drift. As a CE-marked device manufactured under ISO 9001:2015 and ISO 13485:2016 quality systems, the XE 60 conforms to European Machinery Directive 2006/42/EC and Electromagnetic Compatibility Directive 2014/30/EU. Optional IQ/OQ documentation packages are available for regulated environments requiring validation per USP , ISO/IEC 17025, or EU Annex 15.
Software & Data Management
Equipped with an embedded industrial-grade controller featuring RS-485 Modbus RTU and Ethernet TCP/IP interfaces, the XE 60 supports remote monitoring of real-time parameters—including inlet pressure, outlet flow, purity (via integrated O₂ sensor feedback loop), dew point, and system uptime. Logged data is timestamped and exportable in CSV format for integration with LIMS or ELN platforms. Optional PEAK Connect™ software provides graphical trend analysis, alarm threshold configuration, predictive maintenance alerts (e.g., filter saturation, membrane performance drift), and electronic signature capability compliant with 21 CFR Part 11 when deployed with validated authentication protocols.
Applications
- Primary nitrogen supply for up to four high-flow LC-MS systems operating simultaneously (e.g., Q-TOF, Orbitrap, triple quadrupole)
- Gas-assisted sample preparation: nitrogen blow-down evaporation, SPE manifold purge, and inert atmosphere glove boxes
- Carrier and nebulizer gas for HPLC-ELSD and supercritical fluid chromatography (SFC)
- Shield gas for NMR probe cooling and FTMS vacuum chamber conditioning
- Process gas in pharmaceutical stability testing chambers and controlled-environment incubators
FAQ
Does the Infinity XE 60 require an external compressed air source?
Yes. It must be supplied with clean, dry compressed air meeting ISO 8573-1:2010 Class 1.4.1 (oil-free, ≤0.01 µm particles, ≤−40°C pressure dew point). PEAK offers certified air treatment solutions—including refrigerated dryers, coalescing filters, and desiccant dryers—to ensure compliance.
Can the XE 60 be upgraded to higher flow rates after installation?
Yes. Flow capacity can be increased to 428 L/min via firmware update and calibration verification—no hardware modification required—provided inlet air supply and pressure meet specification.
What maintenance intervals are recommended?
Pre-filters require replacement every 6–12 months depending on air quality; membrane modules are rated for >15,000 hours of continuous operation with no scheduled replacement under nominal conditions.
Is the nitrogen purity stable across the full flow range?
Yes. Purity remains within ±0.2% of setpoint across the entire 10–428 L/min range due to closed-loop O₂ monitoring and adaptive airflow control via IMM technology.
