RWD SP0008-R Rat Cerebrovascular and Cardiac Perfusion Surgical Instrument Set
| Brand | RWD |
|---|---|
| Origin | Guangdong, China |
| Manufacturer Type | Direct Manufacturer |
| Country of Origin | China |
| Model | SP0008-R |
| Pricing | Available Upon Request |
Overview
The RWD SP0008-R Rat Cerebrovascular and Cardiac Perfusion Surgical Instrument Set is a purpose-engineered, sterile-ready collection of microsurgical tools designed specifically for preclinical neurovascular and cardiovascular perfusion procedures in Sprague-Dawley, Wistar, and Long-Evans rats (250–450 g). This set supports standardized intracardiac perfusion, transcardial saline/heparin flush, paraformaldehyde fixation, and targeted cerebral or coronary vascular cannulation under stereotaxic or open-chest conditions. All instruments are manufactured from premium-grade, corrosion-resistant 420 stainless steel with precision-ground edges, calibrated tip geometry, and electropolished surfaces to minimize tissue drag and ensure reproducible handling during delicate vascular dissection and cannula insertion.
Key Features
- Optimized ergonomics: Instruments feature balanced weight distribution and micro-textured handles for secure grip during prolonged microsurgery under magnification (10×–25×).
- Tip-specific calibration: Scissors (S14014-12, S12005-10, S11002-08) maintain consistent blade alignment and cutting force across batches; tip radii ≤ 25 µm ensure clean incision without vessel wall tearing.
- Vascular compatibility: Stainless steel microvascular clamps (R31005-06) are sized for rat common carotid artery (0.6–0.8 mm OD), external iliac artery (0.5–0.7 mm OD), and ascending aorta (1.0–1.3 mm OD), with adjustable closure force (0.08–0.12 N) to prevent intimal injury.
- Needle-suture integration: Includes dual suture formats—absorbable PGA (F35305-50, 5-0, ½-circle, 12 mm needle) for vessel anastomosis and non-absorbable nylon (F35205-60, 6-0, 3/8-circle, 14 mm needle) for dural or pericardial closure—both pre-sterilized and individually packaged.
- Modular organization: Supplied in a reusable, autoclavable 31 × 21 cm instrument tray (SP0000-P) with laser-etched compartment labels and ISO-compliant foam inserts conforming to ANSI/AAMI ST79:2023 guidelines for surgical pack integrity.
Sample Compatibility & Compliance
The SP0008-R set is validated for use in adult rat models undergoing terminal perfusion protocols aligned with NIH Guide for the Care and Use of Laboratory Animals and ARRIVE 2.0 reporting standards. All instruments comply with ISO 7153-1:2016 (surgical instruments — materials) and ISO 13485:2016 (medical device quality management systems). Sterilization validation includes 121°C saturated steam autoclaving (15 min dwell time) per EN 285:2015. The set supports GLP-compliant study documentation when used with RWD’s traceable lot-numbered packaging and accompanying Certificate of Conformance (CoC).
Software & Data Management
While the SP0008-R is a manual instrumentation set with no embedded electronics, it integrates seamlessly into digital surgical workflows via RWD’s optional LabSight Pro platform (v3.2+). Users may log instrument usage, sterilization cycles, and procedure timestamps using QR-coded tray labels. Audit trails generated meet FDA 21 CFR Part 11 requirements for electronic records when paired with validated e-signature modules. Instrument-specific maintenance logs—including sharpening frequency and clamp calibration checks—are supported through RWD’s AssetTrack module for IACUC-mandated equipment lifecycle reporting.
Applications
- Transcardial perfusion for immunohistochemistry (IHC) and fluorescence microscopy sample preparation.
- Carotid artery cannulation for real-time cerebral blood flow monitoring (e.g., Laser Doppler or arterial spin labeling MRI).
- Coronary artery ligation or occlusion models requiring precise microvascular control and hemostasis.
- Intracerebral ventricular cannulation and CSF sampling under stereotactic guidance.
- Microvascular anastomosis training and competency assessment in rodent surgery certification programs.
FAQ
Is this set compatible with mice or only rats?
The SP0008-R is optimized for rats (250–450 g). For mice (20–35 g), RWD recommends the SP0007-M Miniature Neurovascular Set, which features scaled-down clamp widths, shorter needle lengths, and finer-tip instruments.
Can the instruments be resterilized multiple times?
Yes—all components are rated for ≥100 autoclave cycles at 121°C per ISO 17664-1:2017. Blade sharpness retention is verified after every 20 cycles using profilometry (Ra ≤ 0.2 µm on cutting edges).
Does the set include a sterilization indicator?
Each tray ships with Class 5 integrating chemical indicators (ISO 11140-1) affixed to internal packaging. Biological indicators (Geobacillus stearothermophilus spore strips) are available separately under catalog number BI-121-R.
Are replacement parts available for individual instruments?
Yes. All items are sold as standalone SKUs (e.g., R31005-06 for microvascular clamps); full replacement kits and consumable refill packs (sutures, needles) are listed in the RWD Preclinical Catalog v2024.
