Sida HS-12A Automatic Static Headspace Sampler
| Brand | Sida |
|---|---|
| Origin | Shanghai, China |
| Manufacturer Type | OEM Manufacturer |
| Regional Classification | Domestic (China) |
| Model | HS-12A |
| Instrument Type | Static Headspace Sampler |
| Automation Level | Fully Automatic |
| Sample Vial Capacity | 12 positions |
| Vial Sizes Supported | 10 mL and 20 mL |
| Carrier Gas Compatibility | Helium, Nitrogen, Hydrogen |
| Maximum Oven Temperature | 200 °C (±0.1 °C stability) |
| Equilibration Time Range | 0–999.9 min |
| Injection Volume Precision | ±1% RSD (typical, with calibrated loop) |
| Thermal Desorption Path | Heated transfer line (up to 220 °C), inert fused-silica or SilcoNert®-treated stainless steel |
Overview
The Sida HS-12A Automatic Static Headspace Sampler is a precision-engineered laboratory instrument designed for the quantitative analysis of volatile and semi-volatile organic compounds (VOCs and SVOCs) in solid and liquid matrices. It operates on the principle of static headspace equilibrium—where a sealed sample vial is heated to a controlled temperature, allowing analytes to partition between the condensed phase and the vapor phase above it. Once thermal and phase equilibrium is achieved, a precise volume of the equilibrated headspace gas is withdrawn via a pressurized, heated sampling loop and transferred directly to a gas chromatograph (GC) injector. This methodology eliminates solvent extraction, derivatization, or manual syringe injection—reducing contamination risk, improving method robustness, and enabling high-throughput, unattended operation across regulated and research environments.
Key Features
- Fully automated 12-position carousel accommodates standard 10 mL and 20 mL crimp-top or screw-cap headspace vials—compatible with ASTM D6866, USP <467>, and ISO 11843-2 workflows.
- Independent, PID-controlled vial oven (range: ambient +5 °C to 200 °C; stability ±0.1 °C) ensures reproducible equilibration conditions critical for method transfer and inter-laboratory comparability.
- Heated, inert sampling pathway—including oven, transfer line (up to 220 °C), and injection loop—minimizes analyte adsorption, cold spots, and carryover. All wetted surfaces are SilcoNert®-coated or fused silica-lined.
- Integrated pressure-balanced sampling mechanism delivers consistent loop fill volume (typically 0.5–2.0 mL, configurable) with ≤1% relative standard deviation under routine operation.
- Modular GC interface supports direct connection to all major GC platforms (Agilent, Thermo Fisher, Shimadzu, PerkinElmer, etc.) via standard septumless or split/splitless injectors—no proprietary adapters required.
- Front-panel touchscreen interface with embedded method storage (≥100 methods), real-time status monitoring, and USB export capability for audit-ready operation logs.
Sample Compatibility & Compliance
The HS-12A is validated for use with aqueous solutions, polymers, soils, biological tissues, pharmaceutical tablets, food matrices, and packaged consumer goods. Its design adheres to core principles of GLP and GMP-compliant laboratories: traceable temperature calibration (NIST-traceable RTD sensors), non-volatile memory for method parameters, and full system self-test at power-on. While not pre-certified for 21 CFR Part 11, the instrument’s firmware architecture supports electronic signature integration and audit trail generation when deployed within validated LIMS or chromatography data systems (CDS) that enforce ALCOA+ data integrity principles.
Software & Data Management
No proprietary PC software is bundled; instead, the HS-12A communicates via industry-standard RS-232/RS-485 serial protocols and optional Ethernet (TCP/IP) for seamless integration into existing CDS environments—including OpenLab CDS, Chromeleon, Empower, and LabSolutions. All method parameters (equilibration time, oven temp, vial pressurization, loop fill/inject timing) are stored internally and recalled by GC trigger signal or external TTL pulse. Event logs—including vial position, timestamp, temperature deviation, and injection success flag—are retained for ≥30 days and exportable as CSV for QA review.
Applications
- Residual solvent analysis in APIs and excipients per ICH Q3C guidelines.
- VOC profiling in drinking water (EPA Method 502.2, 524.4), wastewater, and groundwater.
- Flavor and fragrance compound quantification in beverages, dairy, and fermented foods.
- Migration testing of packaging materials (e.g., PET bottles, laminated films) per EU 10/2011 and FDA 21 CFR 170–189.
- Forensic toxicology screening for ethanol, acetone, and volatile drugs of abuse.
- Quality control of paints, coatings, adhesives, and cleaning agents for VOC content compliance (e.g., CARB, EPA SNAP).
FAQ
Can the HS-12A be integrated with older GC models lacking digital I/O?
Yes—using analog trigger mode (TTL or voltage pulse) or manual start via front-panel initiation. Configuration details are provided in the hardware interface manual.
Is validation documentation (IQ/OQ/PQ protocols) available?
Standard factory test reports and calibration certificates are supplied. Custom IQ/OQ protocols can be developed in collaboration with qualified third-party service providers.
What maintenance intervals are recommended for long-term reliability?
Vial septa should be replaced after every 100 injections; the sampling loop and transfer line require annual inspection and cleaning with methanol followed by nitrogen purge. Full system performance verification is advised every six months.
Does the instrument support dynamic headspace or purge-and-trap functionality?
No—the HS-12A is strictly a static headspace sampler. For dynamic applications, Sida offers the HS-50D series with integrated trap desorption and cryofocusing modules.
Are replacement parts such as vial carriers or heated transfer lines stocked internationally?
Critical spares—including oven blocks, loop assemblies, and SilcoNert®-coated capillaries—are maintained in regional distribution hubs across APAC, EMEA, and North America with typical lead time of 5–10 business days.
