TimePower TP301/TP302 Ultra Pure Water System
| Brand | TimePower |
|---|---|
| Origin | Beijing, China |
| Manufacturer Type | Direct Manufacturer |
| Product Category | Domestic |
| Model | TP301 / TP302 |
| Pricing | Available Upon Request |
| Purified Water Grade | ASTM Type II |
| Resistivity | 18.2 MΩ·cm at 25 °C |
| Heavy Metals & Soluble Silica | < 0.1 ppb |
| Total Organic Carbon (TOC) | < 3 ppb |
| Microbial Count & Endotoxins | < 0.001 EU/mL |
| Particulates (>0.1 µm) | < 1 particle/mL |
Overview
The TimePower TP301/TP302 Ultra Pure Water System is an integrated, laboratory-grade water purification platform engineered for consistent production of ultrapure water meeting stringent international specifications—including ASTM D1193 Type I, ISO 3696 Grade 1, and CLSI EP21-A2 requirements for analytical and life science applications. Utilizing a multi-stage purification architecture—comprising dual-stage reverse osmosis (RO), electrodeionization (EDI), ultrafiltration (UF), and optional UV photo-oxidation—the system delivers water with resistivity up to 18.2 MΩ·cm at 25 °C, TOC 0.1 µm). Designed for continuous operation in regulated environments, the TP301/TP302 supports both point-of-use dispensing and looped distribution configurations, ensuring stable water quality across extended usage cycles without degradation due to biofilm formation or ionic leaching.
Key Features
- Intelligent touchscreen interface with graphical LCD display and tactile membrane keypad for intuitive parameter configuration and real-time status monitoring.
- Integrated self-diagnostic startup sequence verifying pump integrity, sensor calibration, and membrane pressure differentials prior to operational readiness.
- Programmable automatic RO membrane flush cycle triggered by runtime or conductivity threshold, extending membrane service life and maintaining consistent feedwater rejection rates.
- Dual-loop recirculation mode: a closed-loop ultra-pure water circuit maintains constant flow velocity (>0.5 m/s) through the distribution manifold, minimizing microbial adhesion and enabling periodic thermal or chemical sanitization.
- Onboard resistivity and TOC sensors with NIST-traceable calibration protocols; data logging includes timestamped measurements with configurable sampling intervals (1–60 min).
- DC-driven, low-pulsation high-pressure delivery pump compliant with USP requirements for non-metallic wetted parts and minimal particle generation during dispensing.
Sample Compatibility & Compliance
The TP301/TP302 is validated for compatibility with critical downstream instrumentation including HPLC, LC-MS, ICP-MS, atomic absorption spectroscopy (AAS), cell culture media preparation, and molecular biology workflows (e.g., PCR, sequencing library prep). Its output meets or exceeds specifications outlined in ASTM D1193-20 (Type I), ISO 3696:1987 (Grade 1), CLSI EP21-A2 (2021), and pharmacopeial standards including USP Water for Pharmaceutical Purposes and EP 2.2.44 Purified Water. All fluid-contact materials comply with FDA 21 CFR 177.2420 and USP Class VI biocompatibility testing. The system supports audit-ready electronic records aligned with 21 CFR Part 11 requirements when paired with optional time-stamped, user-authenticated data export functionality.
Software & Data Management
The embedded microcontroller firmware enables secure, password-protected access control with role-based permissions (operator, supervisor, administrator). All operational events—including alarm triggers, maintenance alerts, calibration logs, and dispense volume records—are stored locally with 12-month retention capacity. Data export is supported via USB 2.0 port in CSV format, compatible with LIMS integration and GLP/GMP documentation workflows. Optional Ethernet connectivity allows remote monitoring through SNMP-enabled network infrastructure, supporting centralized facility-wide water quality dashboards.
Applications
This system serves as a primary water source in clinical diagnostics laboratories requiring endotoxin-free rinse water for immunoassay platforms; pharmaceutical QC labs performing residual solvent analysis by GC-FID; academic research facilities conducting trace metal quantification via ICP-MS; semiconductor R&D cleanrooms where silica contamination must remain below detection limits; and biomanufacturing suites validating water-for-injection (WFI) pretreatment stages. It is routinely deployed in national metrology institutes for reference material preparation and in environmental testing labs performing ultra-trace PAH analysis by HPLC-FLD.
FAQ
What is the recommended service interval for consumables such as RO membranes and UF cartridges?
RO membranes are rated for 2–3 years under typical municipal feedwater conditions (TDS < 300 ppm); UF cartridges require replacement every 12 months or after 5,000 L throughput—whichever occurs first.
Does the system support validation documentation packages for GMP compliance?
Yes—IQ/OQ documentation templates, as-built P&IDs, and sensor calibration certificates are provided upon request and conform to Annex 15 and ASTM E2500-13 guidance.
Can the TP301/TP302 be integrated into an existing purified water distribution loop?
Yes—standardized 1/4″ Swagelok fittings and pressure-rated stainless steel tubing kits are available for seamless integration with third-party loops operating at ≤5 bar backpressure.
Is UV oxidation included as standard or optional?
UV lamp (185/254 nm dual-wavelength) is optional on TP301 and standard on TP302; it reduces TOC by ≥90% and provides continuous microbial suppression in the final polishing stage.
How does the system ensure endotoxin removal below 0.001 EU/mL?
Through a combination of 10 kDa molecular weight cutoff ultrafiltration and terminal 0.1 µm hydrophilic polyethersulfone (PES) filtration, validated per USP bacterial endotoxin test methodology.
