Precisa 390HA & 390HE Series High-Precision Analytical Balances

Overview

The Precisa 390HA and 390HE Series represent the culmination of Swiss precision engineering in analytical mass measurement. Designed for laboratories demanding traceable, repeatable, and legally defensible weighing results—particularly in pharmaceutical development, reference standard preparation, forensic toxicology, and high-value material formulation—these ultra-micro balances operate on electromagnetic force compensation (EMFC) principles. Each unit integrates a monolithic sensor architecture with active thermal stabilization and dynamic damping control to minimize drift and environmental perturbation. With a readability of 0.01 mg (10 µg) and verified repeatability at ≤0.01 mg under ISO 17025-controlled conditions, the 390HA/HE series meets the metrological requirements for USP <41>, ASTM E898, and OIML R76 Class I performance criteria. The balance’s low-profile weighing pan and minimized cavity volume reduce convective interference and accelerate stabilization—critical when handling volatile solvents or hygroscopic compounds.

Key Features

• 7-inch capacitive touchscreen interface: Glove-compatible, UV-resistant, scratch-proof display with intuitive gesture-based navigation; supports bilingual (English/Chinese) UI without system reboot.
• SmartDraft™ motorized draft shield: Frameless, rail-free design with programmable opening angles (full open / partial open / closed); top glass panel independently controllable for unobstructed access during powder transfer or vessel placement.
• SLS Fully Automatic Linear Calibration: Three-point calibration (zero, 50% capacity, 100% capacity) triggered by time schedule (e.g., daily at 07:00), temperature drift threshold (±2 °C, ±3 °C, or ±5 °C), or manual initiation—ensuring long-term linearity stability per ISO 9001 Clause 7.6.
• TLS Infrared Touchless Control: Dual-side IR sensors enable hands-free tare, zero, print, and door actuation; configurable for left/right hand, short/long dwell, and height-specific activation zones to prevent cross-contamination in sterile or cytotoxic workflows.
• ECS Electrostatic Charge Neutralization: Integrated AC-pulse discharge circuitry automatically eliminates residual static from samples upon door closure—validated per IEC 61340-5-1 for electrostatic-sensitive environments.
• AOS Environmental Monitoring System: Onboard barometric pressure, ambient temperature, and relative humidity sensors feed real-time data into the BEST (Buoyancy Error Suppression Technology) algorithm for automatic air density correction—eliminating manual input errors in density-dependent applications.

Sample Compatibility & Compliance

The 390HA/HE accommodates standard ISO/IEC 17025-compliant sample containers—including volumetric flasks, weighing boats, and custom vials—within its optimized cavity geometry. Its low-center-of-gravity base and reinforced anti-vibration feet ensure stable operation on shared lab benches or isolation tables. All firmware and software modules comply with FDA 21 CFR Part 11 requirements: electronic signatures, role-based user authentication (administrator/operator/auditor), and tamper-evident audit trails with SHA-256 hashing. Every weight event—including calibration, tare, print, and parameter change—is timestamped, user-attributed, and immutably logged. Data export is supported via USB mass storage (CSV, PDF, XML) or network protocols (FTP, HTTP POST) for integration into LIMS or ELN systems.

Software & Data Management

Precisa BalanceSuite™ firmware includes embedded database management with searchable audit logs filtered by date range, operator ID, sample ID, or event type (e.g., “calibration,” “overload warning”). Exported records contain digital signatures and cryptographic checksums for regulatory submission. Optional BalanceLink™ PC software enables remote configuration, batch report generation, statistical process control (SPC) charting, and automated compliance reporting aligned with ISO/IEC 17025 Clause 7.7 and EU Annex 11. All data transfers adhere to TLS 1.2 encryption standards; wireless options (Wi-Fi/Bluetooth) support IEEE 802.11ac and Bluetooth 5.0 LE with WPA3 enterprise authentication.

Applications

• Pharmaceutical QC/QA: Weighing of reference standards, placebo formulations, and controlled substances per USP <1251> and ICH Q5C guidelines.
• Materials Science: Accurate dosing of nanomaterials, catalysts, and battery electrode slurries where ±0.01 mg deviation impacts stoichiometric ratios.
• Clinical Research: Preparation of isotopically labeled tracers and radiopharmaceutical intermediates requiring ALARA-compliant handling.
• Academic Metrology Labs: Traceable mass dissemination, gravimetric titration, and calibration of secondary standards against NIST-traceable references.
• Environmental Testing: Quantification of microplastics, airborne particulates, and soil extract residues using EPA Method 1694-compliant protocols.

FAQ

What is the difference between the 390HA and 390HE models?
The 390HA is configured for general high-accuracy analytical use with standard environmental compensation; the 390HE adds enhanced vibration immunity, extended temperature compensation range (−10 °C to +40 °C), and optional internal validation hardware for GxP-regulated environments.
Does the balance support GLP-compliant data archiving?
Yes—audit trail records include operator ID, timestamp (UTC), action performed, pre-/post-values, and digital signature hash. Logs are write-once/read-many (WORM) and exportable in FDA-accepted formats.
Can the touchscreen be operated with nitrile gloves?
Yes—the capacitive screen is calibrated for glove-mode sensitivity and meets EN 374-2 mechanical resistance standards.
Is external calibration required after SLS automatic calibration?
No—SLS satisfies routine verification per USP <41> and ISO 17025; however, periodic external verification using certified weights (e.g., Class E2 or F1) is recommended every 3–6 months depending on usage intensity and risk assessment.
How does BEST buoyancy correction improve accuracy?
BEST dynamically calculates air density from real-time AOS sensor inputs and applies Archimedean correction to displayed mass values—reducing typical buoyancy-induced errors of 0.03–0.12% in humid or high-altitude labs.