Shanghai Yarong YRDC-0506 Cryogenic Circulating Thermostat

Overview

The Shanghai Yarong YRDC-0506 Cryogenic Circulating Thermostat is a precision temperature control system engineered for laboratory environments requiring stable, uniform thermal fields across a broad operating range (−5 °C to +100 °C). Designed specifically to serve as a reliable cold/hot bath for rotary evaporators, spectrophotometers, calorimeters, and other externally coupled analytical instruments, it employs a dual-mode thermoregulation architecture: high-efficiency hermetic compressor-based refrigeration combined with PID-controlled resistive heating. Temperature sensing is performed via a calibrated Pt100 platinum resistance thermometer mounted directly in the bath fluid path, ensuring traceable accuracy and minimal thermal lag. The system’s ±0.02 °C stability (measured in water or anhydrous ethanol at 25 °C) meets the stringent requirements of method-critical applications in pharmaceutical QC, polymer characterization, and enzymatic kinetics studies where thermal drift can significantly affect reaction rates or phase behavior.

Key Features

• Microprocessor-based PID controller with auto-tuning capability—enables rapid convergence to setpoint and minimizes overshoot during ramping
• High-reliability sealed compressor and optimized heat exchanger design—delivers fast cooling from ambient to −5 °C in under 35 minutes
• Dual digital LED displays—one for set temperature (0.1 °C resolution), one for real-time bath temperature—ensuring immediate visual verification of thermal status
• 304 stainless steel inner tank, impeller, and circulation pump housing—resistant to corrosion from aqueous and organic media including ethanol, methanol, and glycol-water mixtures
• Integrated internal/external recirculation mode—with adjustable flow rate up to 8 L/min and dedicated external port for secondary temperature zone establishment
• Foldable side handles and low-center-of-gravity chassis—facilitates safe repositioning without compromising structural rigidity
• Open-circuit sensor detection—automatically alerts operator upon Pt100 disconnection or failure, preventing uncontrolled operation

Sample Compatibility & Compliance

The YRDC-0506 accommodates standard laboratory glassware up to 150 mm in footprint and depth, making it compatible with most rotary evaporation flasks (up to 5 L), jacketed reactors, and immersion-type probes. Its bath geometry supports both direct immersion and external jacketed circulation configurations. While not certified to ISO/IEC 17025 or ASTM E2877 for metrological traceability out-of-the-box, the system is fully configurable for GLP-compliant workflows: optional data logging modules support time-stamped temperature records with audit trail functionality, and its stable thermal output satisfies the environmental control prerequisites outlined in USP , ISO 17025 Clause 5.4.2, and FDA 21 CFR Part 11 when integrated into validated instrument networks.

Software & Data Management

The thermostat operates autonomously via front-panel controls; no proprietary software is required for basic operation. However, optional RS232 or USB-to-serial interface kits enable integration with LabVIEW, MATLAB, or custom SCADA systems for remote setpoint programming, real-time temperature streaming, and automated ramp-soak-hold protocols. Logged data (timestamp, setpoint, actual temperature, error deviation) can be exported in CSV format for post-processing in Excel or statistical analysis packages. All firmware versions include password-protected parameter locking to prevent accidental configuration changes during routine use—supporting multi-user lab environments governed by SOP-driven operations.

Applications

• Rotary evaporation support—maintaining precise condenser and bath temperatures for solvent recovery under reduced pressure
• Calibration of temperature-sensitive detectors (e.g., IR cells, thermocouple reference junctions, RTD standards)
• Controlled-rate crystallization studies in API development and polymorph screening
• Viscosity measurements requiring constant-temperature sample conditioning per ASTM D445 or ISO 3104
• Stability testing of biologics and excipients under accelerated aging conditions (ICH Q1A)
• Thermal preconditioning of samples prior to DSC, TGA, or DMA analysis

FAQ

What circulating fluids are compatible with the YRDC-0506?

Deionized water, 99.9% anhydrous ethanol, and aqueous glycol mixtures (≤60% v/v) are approved. Avoid chlorinated solvents, acetone, or strong acids due to material compatibility constraints.
Can the unit maintain −5 °C continuously with external load?

Yes—under no-flow conditions with a 6 L water bath, continuous operation at −5 °C is achievable. With full external circulation (8 L/min), sustained sub-zero operation requires ambient room temperature ≤25 °C and adequate ventilation.
Is the temperature calibration traceable to national standards?

The factory-installed Pt100 sensor is calibrated against NIST-traceable references. End users may perform field verification using a certified reference thermometer (e.g., Fluke 1523/1524) and document deviations per internal QA procedures.
Does the unit comply with electrical safety standards for international labs?

It conforms to IEC 61010-1:2010 for laboratory equipment safety and carries CE marking for EMC and LVD directives. For North American deployment, UL/cUL listing requires third-party evaluation of the final installed configuration.
How often does the refrigerant require servicing?

Under normal operating conditions and proper ventilation, the sealed R134a refrigeration circuit is maintenance-free for ≥8 years. Annual inspection of condenser coil cleanliness and fan function is recommended to sustain optimal thermal performance.