BOXUN BXM-85VF Vertical Steam Autoclave

Overview

The BOXUN BXM-85VF Vertical Steam Autoclave is a fully integrated, Class B pre-vacuum and steam-flush pressure sterilization system engineered for high-reliability sterilization of heat- and moisture-stable laboratory and clinical loads. It operates on the fundamental principle of saturated steam under controlled pressure and temperature to achieve microbial inactivation through protein denaturation and nucleic acid disruption. Designed in accordance with ISO 17665-1 (Sterilization of health care products — Moist heat — Part 1: Requirements for the development, validation and routine control of a sterilization process for medical devices), the BXM-85VF delivers validated lethality (F₀) across heterogeneous loads—including wrapped instruments, porous textiles, liquid media in large-volume containers (up to 5 L), glassware, and biohazardous waste—without compromising cycle integrity or material compatibility.

Key Features

• PMMA II microprocessor-based control system with 10.1-inch capacitive touchscreen interface for real-time visualization of phase progression, chamber pressure, jacket temperature, load temperature (via optional probe), and dynamic F₀ calculation.
• Positive-pressure pulsing technology with up to 6 programmable air removal cycles ensures complete cold-air evacuation prior to sterilization—critical for achieving uniform steam penetration in dense, layered, or wrapped loads.
• Vacuum-assisted drying function (80–130 °C, adjustable duration up to 100 minutes) eliminates post-cycle handling of moist instruments or textiles, mitigating recontamination risk and supporting ISO 15883-compliant aseptic workflow continuity.
• Triple-stage rapid cooling system: integrated condenser + forced-air cooling + secondary water-cooling circuit reduces chamber cooldown time by >40% versus conventional gravity-displacement units, enabling earlier safe door opening and throughput optimization.
• Three-tier user permission architecture (Engineer / Administrator / Operator) with password protection and audit-trail-capable event logging—aligned with GLP and GMP documentation requirements per FDA 21 CFR Part 11 Annex 11 principles.
• Comprehensive safety redundancy: independent electronic overpressure cutoff, mechanical pressure lock, lid self-check interlock, dry-run protection, overtemperature shutdown, ground-fault circuit interruption, and automatic emergency venting at 0.25 MPa.

Sample Compatibility & Compliance

The BXM-85VF accommodates standard laboratory sterilization loads including but not limited to: liquid culture media (in bottles ≤5 L), stainless-steel surgical instruments, cotton gauze packs, glass pipettes and flasks, rubber tubing, and regulated biological waste. Its Class B cycle classification permits processing of porous, hollow, and multi-layered items requiring vacuum-assisted air removal. The unit meets EN 285:2015 (Large sterilizers), EN 13060:2014 (Small steam sterilizers), and GB/T 30690–2014 (Chinese national standard for small autoclaves). Optional validation accessories—including calibrated PT100 load temperature sensors, 0.2 µm sterile exhaust filters, and thermal printer modules with USB data export—support IQ/OQ/PQ protocol execution and regulatory submissions.

Software & Data Management

The embedded PMMA II OS supports 8 preloaded sterilization programs (e.g., Liquids, Instruments, Wrapped Packs, Waste) and 6 fully customizable cycles with independent setpoints for pre-vacuum depth, steam flush count, sterilization hold time, drying ramp rate, and cooling delay. All operational events—including door status, pressure transients, temperature deviations, alarm triggers, and user logins—are timestamped and stored locally for ≥10,000 cycles. Optional thermal printer output includes date/time stamp, cycle ID, chamber/load temperatures, pressure profile, and calculated F₀ values when paired with a validated probe—enabling traceability for ISO 13485 quality system audits.

Applications

This autoclave serves core sterilization needs across academic research laboratories, pharmaceutical QC labs, clinical diagnostics centers, and veterinary facilities. Typical use cases include: terminal sterilization of microbiological growth media; depyrogenation of glassware prior to aseptic cell culture; preparation of sterile surgical kits for animal surgery units; decontamination of BSL-2 waste prior to autoclave validation; and routine sterilization of reusable lab textiles where residual moisture poses contamination or corrosion risks. Its 85 L chamber volume supports batch processing of up to 12 standard instrument trays or 40 L of liquid media per cycle.

FAQ

Does the BXM-85VF support F₀-based cycle validation?
Yes—when equipped with an optional calibrated load temperature sensor and thermal printer, the system calculates and prints real-time F₀ values compliant with USP and EU GMP Annex 1 requirements.
Can it operate reliably at high-altitude sites?
Yes—the boiling point adjustment function allows manual offset calibration of temperature setpoints to compensate for reduced atmospheric pressure, ensuring accurate sterilization temperatures up to 3000 m elevation.
Is remote monitoring or network connectivity supported?
Standard configuration includes two RS-485 ports for integration into building management systems (BMS) or centralized lab monitoring platforms via Modbus RTU protocol; Ethernet or Wi-Fi modules are available as OEM-engineered add-ons.
What maintenance intervals are recommended?
Daily: chamber seal inspection and drain line flush. Quarterly: pressure transducer calibration verification and vacuum pump oil replacement. Annually: full IQ/OQ requalification with certified third-party service provider.
Are validation accessories supplied with the unit?
A validation port (G1/2A threaded) and one waterproof power outlet are standard. Load temperature sensors, sterile exhaust filters, and thermal printers are optional accessories ordered separately with documented metrological traceability.