Boxun BXM-85VE Vertical Steam Autoclave
| Brand | Boxun |
|---|---|
| Origin | Shanghai, China |
| Model | BXM-85VE |
| Instrument Type | Vertical Autoclave |
| Max Temperature | 150 °C |
| Max Pressure | 0.38 MPa |
| Chamber Dimensions | Ø400 × 725 mm |
| External Dimensions | 535 × 640 × 1165 mm |
| Chamber Volume | 85 L |
| Temperature Uniformity | ±0.5 °C |
| Temperature Fluctuation | < +1 °C |
| Sterilization Time Range | 0–120 min (customizable up to 6000 min) |
| Power Supply | ~220 V ±22 V, 50 Hz ±1 Hz |
| Ambient Operating Conditions | 5–40 °C, 20–80% RH |
Overview
The Boxun BXM-85VE Vertical Steam Autoclave is a CE-compliant, microprocessor-controlled laboratory sterilization system engineered for precision, repeatability, and regulatory traceability in biosafety-critical environments. It operates on the validated principle of saturated steam under pressure—adhering to ISO 17665-1 (Sterilization of health care products — Moist heat) and supporting compliance with USP , EN 285, and FDA 21 CFR Part 11 when integrated with audit-trail-capable software and electronic signatures. Designed for routine sterilization of culture media, glassware, surgical instruments, labware, and biohazardous waste, the BXM-85VE delivers consistent lethality (F0) through tightly controlled thermal profiles, real-time chamber monitoring, and programmable phase transitions—including pre-vacuum pulses, dynamic air removal, and graded depressurization.
Key Features
- PMMA I intelligent microcomputer control system with a large-format capacitive touchscreen interface for intuitive navigation and real-time visualization of temperature, pressure, time, and process stage diagrams.
- Eight pre-programmed sterilization cycles (e.g., liquid, solid, instrument, waste) plus six user-definable protocols with full parameter granularity—including adjustable vacuum levels, pulse count, heating/cooling ramp rates, and dwell times.
- Positive-pressure pulse air removal system with six-stage programmable cold-air evacuation—ensuring complete air displacement prior to sterilization for uniform steam penetration and elimination of cold spots.
- Multi-tiered safety architecture: dual mechanical door interlock with pressure-actuated auto-locking, lid closure self-check, independent electronic overpressure cutoff, overtemperature shutdown, dry-run protection, leak detection, short-circuit and overload protection, and insulated external surfaces meeting IEC 61010-1 surface temperature limits.
- Engineered cooling system combining forced-air convection, secondary water cooling, and integrated condenser—reducing post-cycle cooldown time by up to 40% versus conventional air-cooled units, enabling faster throughput and reduced operator wait time.
- Three-level access control (Engineer, Administrator, Operator) with password-protected parameter modification, cycle initiation, and data export functions—supporting GLP/GMP role-based accountability and change management protocols.
Sample Compatibility & Compliance
The BXM-85VE accommodates standard autoclave-compatible loads including PET/PP/PC containers, stainless-steel instruments, borosilicate glassware, wrapped surgical packs, and sealed liquid media bottles. Its Ø400 × 725 mm cylindrical chamber supports two standard 370 × 285 mm wire mesh baskets. Optional validation accessories—including calibrated Pt100 sample temperature probes, G1/2A threaded validation port adapters, and 0.2 µm high-temperature/pressure-rated exhaust filters—enable IQ/OQ/PQ execution per ISO 13485 and Annex 1 requirements. All firmware logs include timestamped event records (e.g., door open/close, pressure rise/fall, temperature deviation alerts), facilitating FDA 21 CFR Part 11-compliant electronic record retention when paired with validated data management software.
Software & Data Management
The built-in controller stores up to 1000 cycle logs with full parameter snapshots. Optional thermal printer (SPR brand, thermal-sensitive paper) provides hard-copy output of date/time, setpoints, actual curves, F0 calculation (when used with sample probe), and alarm history—with embedded USB storage for raw data backup. RS-485 serial interfaces support integration into centralized lab monitoring systems (e.g., LabVantage, Thermo Fisher SampleManager) for automated reporting and audit trail aggregation. Firmware supports configurable data export formats (CSV, XML) and includes digital signature fields for electronic approval workflows compliant with ALCOA+ principles.
Applications
This autoclave serves core sterilization needs across academic research laboratories, pharmaceutical QC/QA labs, clinical diagnostics facilities, and contract manufacturing organizations (CMOs). Typical use cases include: terminal sterilization of microbiological growth media (e.g., LB, TSA, Sabouraud); depyrogenation of glass vials and syringes; decontamination of BSL-2 waste streams; preparation of sterile saline and buffer solutions; and validation of steam penetration in porous load configurations. Its 100-hour delayed start function enables off-peak operation scheduling, while altitude-compensated boiling point adjustment ensures accurate temperature setpoint delivery at elevations up to 3000 m.
FAQ
What is the maximum allowable working pressure and corresponding temperature range?
The BXM-85VE is rated for a maximum design pressure of 0.38 MPa (55 psia), with operational sterilization temperatures spanning 105–135 °C at 0.22 MPa (32 psia) nominal working pressure.
Does the unit support F0-based cycle validation?
Yes—when equipped with an optional calibrated sample temperature probe and thermal printer, the system calculates and prints real-time F0 values synchronized with chamber temperature and pressure data.
Is remote monitoring or network connectivity available?
The dual RS-485 ports enable Modbus RTU communication for integration with SCADA or LIMS platforms; Ethernet or Wi-Fi modules are not natively supported but may be added via third-party industrial gateways.
What safety certifications does the BXM-85VE carry?
It complies with IEC 61010-1 (Safety Requirements for Electrical Equipment for Measurement, Control, and Laboratory Use) and meets electromagnetic compatibility (EMC) requirements per IEC 61326-1; CE marking is applied per Machinery Directive 2006/42/EC and Pressure Equipment Directive 2014/68/EU.
Can the autoclave be validated for GMP environments?
Yes—its deterministic control logic, non-volatile cycle logging, user-access hierarchy, and optional validation hardware meet foundational requirements for IQ/OQ execution under EU GMP Annex 15 and WHO TRS 986. Full qualification requires site-specific protocol development and third-party verification.
