SOCOREX 825 Adjustable-Volume Single-Channel Pipette

Overview

The SOCOREX 825 Adjustable-Volume Single-Channel Pipette is a precision-engineered manual liquid handling instrument designed for high-reproducibility volumetric transfer in regulated laboratory environments. Based on air displacement principle, the 825 series employs a corrosion-resistant stainless-steel piston and hermetically sealed O-ring system to ensure consistent aspiration and dispensing across its full volume range—from 0.1 µL to 1000 µL—depending on the selected variant. Its modular architecture supports ISO 8655-compliant calibration and traceable performance verification, making it suitable for applications requiring GLP/GMP alignment, including method validation, reference standard preparation, and quality control testing in pharmaceutical, clinical diagnostics, and academic research laboratories.

Key Features

• Human-centered ergonomics: Lightweight construction (≤105 g depending on variant) and low plunger activation force reduce operator fatigue during repetitive pipetting tasks—even when wearing gloves.
• JUSTIP™ adjustable tip ejector: A patented height-adjustable ejection rod enables optimal mechanical engagement with diverse tip geometries—including ultra-low retention, filtered, and extended-length tips—without compromising seal integrity or ejection reliability.
• Full-unit autoclavability: All components—including shaft, plunger, and housing—are rated for repeated sterilization at 121 °C, 100 kPa, for 20 minutes, eliminating cross-contamination risks in sterile workflows.
• Front-facing digital volume display: Large, high-contrast digits oriented toward the user improve readability and minimize parallax error during volume setting and verification.
• Color-coded volume identification: Integrated color bands on the upper housing provide rapid visual confirmation of nominal range (e.g., blue for 10–100 µL), supporting error-prevention protocols in multi-pipette setups.
• Tool-free one-touch calibration: Internal adjustment via rotary calibration rod allows field recalibration without disassembly; calibration lock (LOCK/CAL switch) prevents inadvertent volume drift during routine use.
• Burette adapter compatibility: Optional Pasteur pipette adapters support direct aspiration from 2 mL or 5 mL glass capillaries—enabling solvent-sensitive or viscous sample handling without polypropylene tip interference.

Sample Compatibility & Compliance

The SOCOREX 825 accommodates a broad spectrum of aqueous, buffered, and mildly organic solutions. Its chemically inert internal surfaces (anodized aluminum housing, PTFE-coated piston, and silicone-free lubricants) resist degradation from common solvents (e.g., ethanol, isopropanol, ≤10% DMSO). All variants comply with ISO 8655-2 (volumetric accuracy), ISO 8655-5 (calibration procedures), and IVD Directive 98/79/EC. CE marking confirms conformity with essential health and safety requirements under EU regulatory frameworks. For FDA-regulated environments, the device supports audit-ready documentation through optional calibration certificates traceable to NIST standards.

Software & Data Management

While the 825 is a fully manual instrument, its design integrates seamlessly into digital lab ecosystems. Each pipette carries a unique serial number engraved on the barrel, enabling asset-level tracking in LIMS or CMMS platforms. Calibration records—including date, technician ID, pre-/post-calibration verification data, and uncertainty budgets—can be archived in accordance with 21 CFR Part 11 requirements when paired with validated electronic logbooks. SOCOREX provides downloadable calibration templates compliant with ISO/IEC 17025 documentation standards, facilitating internal audit readiness and external accreditation reviews.

Applications

• Quantitative PCR (qPCR) master mix preparation requiring sub-microliter precision at low volumes (e.g., 0.5–10 µL range).
• Cell culture media supplementation with growth factors or antibiotics where volumetric fidelity directly impacts assay reproducibility.
• Clinical chemistry dilutions under CLIA and CAP guidelines, particularly in hematology and coagulation testing workflows.
• Reference material dilution series for HPLC and LC-MS method development, where CV < 0.3% is mandated for linearity assessment.
• High-throughput screening plate setup using 96- or 384-well formats, leveraging tip compatibility with automated tip loaders.

FAQ

How often should the SOCOREX 825 be calibrated?
Calibration is recommended every 6 months under routine use; maximum interval shall not exceed 12 months. Frequency may increase based on usage intensity, environmental conditions (e.g., temperature/humidity fluctuations), or regulatory requirements (e.g., ISO 15189, USP ).

Can the 825 be autoclaved with the tip cone assembled?
Yes—full-unit autoclaving is supported. However, disposable tips must be removed prior to sterilization. Reassemble only after complete drying to prevent condensation-induced seal compromise.

What is the proper storage posture post-use?
Always return the volume setting to its maximum value and store vertically in a dedicated pipette stand. Horizontal placement risks fluid backflow into the internal mechanism, potentially degrading piston seals or lubricant integrity.

Is third-party tip compatibility validated?
SOCOREX validates performance exclusively with original Ultra-Low Retention (ULR) tips. Use of non-certified tips may affect accuracy, precision, and long-term mechanical reliability—particularly concerning JUSTIP™ ejection consistency and seal formation.

How is calibration traceability maintained?
Each calibration event must be documented with gravimetric measurement data (using Class I or II analytical balances per ISO 8655-6), ambient conditions, and uncertainty calculations. SOCOREX China’s accredited calibration lab issues certificates traceable to national metrology institutes (NIM, PTB, or NIST equivalents).