ChemTron TH3-KE-025 Benchtop Climate Chamber

Overview

The ChemTron TH3-KE-025 is a precision-engineered benchtop climate chamber designed for laboratories requiring rigorous, repeatable environmental simulation under controlled temperature and relative humidity conditions. Built in Germany and compliant with DIN 12880 and IEC 60068-3 standards, this unit employs a dual-loop PID control architecture—separate proportional-integral-derivative algorithms governing thermal and hygral subsystems—to maintain stable, traceable test environments. Its compact footprint (611 × 878 × 911 mm) enables integration into space-constrained analytical labs, QC suites, or stability testing workstations without compromising performance integrity. The chamber’s core function is to replicate defined climatic profiles for accelerated aging, material compatibility assessment, pharmaceutical stability studies (ICH Q1A–Q1E), and electronic component validation—supporting both static setpoint operation and dynamic multi-segment programming.

Key Features

• Robust dual-seal door system with heated anti-condensation glass viewport (220 × 300 mm) and integrated LED status indicators for remote operational awareness
• Independent safety architecture: dual overtemperature protection (electronic + mechanical), low-water-level cutoff, door-open interlock, compressor overload protection, and ground-fault circuit interruption
• Modular humidification system with external water reservoir and self-cleaning capability; compatible with deionized water (conductivity ≤20 µS/cm, pH 2–7.2)
• High-efficiency insulation using CFC-free polyurethane foam (≥80 mm thickness) ensures surface temperatures remain below 60 °C even at maximum operating temperature
• 5.6-inch color touchscreen HMI with graphical real-time display of chamber status, trend logging, and intuitive navigation—no external PC required for basic operation
• Programmable controller supporting up to 100 user-defined test sequences, each containing up to 100 segments (max. 2000 total segments), with segment duration configurable from 1 minute to 99 h 59 min
• Standard RS-232 interface; optional RS-485 expansion enabling centralized monitoring and control of up to 32 units via dedicated software suite

Sample Compatibility & Compliance

The TH3-KE-025 accommodates standard laboratory sample carriers: two included stainless-steel wire shelves (adjustable in 20-mm increments), each rated for 25 kg load capacity (total 65 kg). Its internal dimensions (350 × 220 × 350 mm W×D×H) allow placement of ISO-standard stability chambers trays, petri dishes, vials, PCB assemblies, and polymer specimens. All materials contacting the test environment—including chamber walls, shelf supports, and gasketing—are chemically inert and non-outgassing, ensuring no interference with sensitive assays or regulatory submissions. The unit meets essential requirements for GLP-compliant environments, including audit-trail-capable data logging (Excel/Text export), calibration traceability, and programmable auto-recall of setpoints after power interruption. It is routinely deployed in pharmaceutical stability programs aligned with ICH guidelines and fulfills prerequisite conditions for USP , FDA 21 CFR Part 11 (when paired with validated LC GreenBox mobile gateway), and ISO 17025-accredited testing workflows.

Software & Data Management

Embedded firmware supports full-cycle data acquisition at user-selectable intervals (1–600 seconds), storing time-stamped temperature and humidity values internally for ≥30 days. Exported datasets retain metadata (operator ID, program name, start/stop timestamps, alarm logs) in CSV-compatible format for downstream statistical analysis in JMP, Minitab, or Python-based validation scripts. Remote supervision is enabled via ChemTron’s LC GreenBox ecosystem—an optional hardware gateway that provides secure TLS-encrypted MQTT communication to cloud platforms or on-premise LIMS. Firmware updates are performed via USB stick, with version history and checksum verification embedded in the bootloader. Calibration parameters (offset, gain) are stored separately from operational settings and require password-protected access—ensuring metrological integrity across maintenance cycles.

Applications

• Pharmaceutical stability testing per ICH Q1A(R3), Q5C, and Q5D protocols for active pharmaceutical ingredients (APIs) and finished dosage forms
• Accelerated corrosion testing of metallic substrates per ASTM D2247 and ISO 9223
• Thermal cycling validation of adhesives, encapsulants, and composite laminates in aerospace R&D
• Humidity-induced stress screening of microelectromechanical systems (MEMS) and printed circuit boards (PCBs)
• Long-term storage condition qualification for diagnostic reagents, vaccines, and biologics
• Material science investigations into hygroscopic expansion, phase transitions, and moisture diffusion kinetics

FAQ

What is the minimum and maximum operating temperature range for the TH3-KE-025?

The TH3-KE series operates from −40 °C to +150 °C, with humidity control active between 20–95 %RH.
Does the chamber support automated calibration verification?

Yes—the integrated controller includes automatic temperature offset adjustment and supports external reference probe input for periodic verification per ISO/IEC 17025.
Can the unit be integrated into an existing building management system (BMS)?

Via optional RS-485 Modbus RTU protocol implementation, the TH3-KE-025 can transmit real-time sensor values and alarm states to third-party SCADA or BMS platforms.
Is the water reservoir accessible without tools?

Yes—the front-accessible humidifier tank features quick-release latches and a transparent level indicator, allowing visual inspection and refill without disassembly.
What documentation is provided for regulatory submissions?

Factory-issued IQ/OQ protocols, traceable calibration certificates (NIST-traceable references), and a complete technical file compliant with EU Machinery Directive 2006/42/EC and EMC Directive 2014/30/EU are supplied with each unit.