ChemTron DB-2000 Standard High-Pressure Reactor System

Overview

The ChemTron DB-2000 Standard High-Pressure Reactor System is an engineered solution for controlled chemical synthesis, catalytic testing, hydrogenation, oxidation, supercritical fluid reactions, and kinetic studies under elevated pressure and temperature conditions. Built upon a modular architecture, the system operates on the principle of sealed batch reaction within a mechanically robust, corrosion-resistant vessel—designed to maintain integrity at up to 200 bar while enabling precise thermal and pressure regulation. Its core construction utilizes electropolished 316Ti stainless steel, with all wetted surfaces—including reactor body, lid, internal dip tubes, valves, and fittings—fully lined with chemically inert polytetrafluoroethylene (PTFE). This full-liner configuration eliminates crevice corrosion risks and ensures compatibility with aggressive reagents (e.g., strong acids, halogenated solvents, HF, HNO₃, and supercritical CO₂), distinguishing it from conventional partial-lining designs. The reactor meets mechanical design standards aligned with PED 2014/68/EU for pressure equipment and incorporates certified safety components—including a Monel rupture disc with PFA protective foil and traceable calibration documentation.

Key Features

• Quick-clamp closure mechanism: Tool-free, hand-tightened sealing with ergonomic torque feedback—enabling repeatable leak-tight assembly in <30 seconds without wrenches or alignment fixtures.
• Full PTFE internal lining: Seamless, machined PTFE inserts for vessel and lid (part no. 5715063), ensuring complete isolation of process media from metallic substrates—even during extended exposure to corrosive or oxidizing environments.
• High-integrity sealing system: Interchangeable O-ring options including PTFE (5757926), standard FPM/Viton (5757924), high-performance FFKM/Kalrez (5054130), and specialty Viton 890 (5054131) rated for supercritical CO₂ service.
• Integrated pressure & temperature monitoring: Factory-calibrated 0–200 bar pressure transducer (5725660) with ceramic (Al₂O₃) or Kalrez-wetted elements; K-type NiCrNi thermocouple (5781240) housed in PTFE-sheathed SS316Ti dip tube for accurate bulk-phase measurement.
• Modular interface compatibility: All ports conform to G3/8″ BSP threading; includes pre-installed vent valve, rupture disc holder, and standardized flange patterns for rapid integration of auxiliary modules (gas dosing, liquid addition, condensation, sampling).
• Thermal management readiness: Compatible with CHM-2000 electric heating jacket (2000 W, 50–300 °C), requiring external PID controller (e.g., Julabo LC6) for closed-loop temperature regulation with overheat protection.

Sample Compatibility & Compliance

The DB-2000 supports heterogeneous and homogeneous reactions involving organic, inorganic, organometallic, and polymeric systems. Its PTFE-lined geometry accommodates suspensions, slurries, viscous media, and gas–liquid–solid multiphase mixtures without degradation of sensor accuracy or seal performance. The system complies with material compatibility guidelines outlined in ASTM D471 (elastomer resistance), ISO 15142-1 (pressure equipment materials), and USP (analytical instrument qualification). When configured with optional automation software, it supports ALCOA+ data integrity principles and satisfies audit requirements for FDA 21 CFR Part 11 (electronic records/signatures) and EU Annex 11 (computerized systems) when deployed in regulated QC/QA laboratories.

Software & Data Management

An optional PC-based control interface enables automated execution of multi-step reaction protocols—including ramp/soak temperature profiles, sequential gas pressurization, timed reagent injection, and real-time logging of pressure, temperature, and stirrer speed (when paired with magnetic or mechanical drive units). Raw data streams are timestamped and stored in secure, non-erasable binary files compliant with ICH M7 and GLP archival standards. Export formats include CSV and XML for integration into LIMS or ELN platforms. Audit trails record user actions, parameter changes, and system events with immutable timestamps—supporting full traceability per 21 CFR Part 11 §11.10(b).

Applications

• Catalytic hydrogenation and hydroformylation under H₂ pressures up to 100 bar
• Supercritical CO₂-mediated extractions and polymerizations
• Acid-catalyzed esterifications and Friedel–Crafts reactions in corrosive media
• Hydrothermal synthesis of metal oxides and MOFs
• High-pressure oxidation using O₂ or air, including nitric acid digestion protocols
• Reaction calorimetry (when coupled with calibrated cooling jackets)
• Process safety screening (e.g., adiabatic temperature rise, pressure buildup rate)

FAQ

What is the maximum allowable working pressure of the DB-2000 reactor?
The DB-2000 is rated for continuous operation up to 200 bar, with a certified rupture disc set at exactly 200 bar (Monel substrate, PFA-coated, individually tested and certified).
Can the reactor be used with hydrofluoric acid (HF)?
Yes—the full PTFE lining, PTFE O-rings, and ceramic/Kalrez-wetted pressure sensor provide full compatibility with anhydrous and aqueous HF solutions below 200 °C.
Is the temperature sensor calibrated and traceable to NIST standards?
Each T-sensor (5781240) is supplied with a manufacturer’s calibration certificate; optional third-party NIST-traceable recalibration is available upon request.
Does the system support vacuum operation prior to pressurization?
Yes—standard configuration includes a vent valve and compatible vacuum-rated PTFE tubing (5701017), allowing evacuation to ≤1 mbar before introduction of reactant gases.
Are spare PTFE liners and O-rings available as consumables?
All PTFE inserts (5715063), rupture discs (5759480), and O-ring variants (5757926, 5757924, etc.) are stocked as field-replaceable parts with documented shelf-life and lot traceability.