Thermo Fisher TSP P100 Dual-Piston HPLC Pump
| Brand | Thermo Fisher |
|---|---|
| Origin | Canada |
| Manufacturer Type | Authorized Distributor |
| Origin Category | Imported |
| Model | P100 |
| Product Category | Chromatography |
| Operational Age | 5–7 Years |
| Warranty | 6 Months |
| Condition | Refurbished & Fully Tested |
Overview
The Thermo Fisher TSP P100 is a high-performance, dual-piston, pulseless high-pressure liquid chromatography (HPLC) pump engineered for precision solvent delivery in analytical and preparative LC systems. Designed with a microprocessor-controlled dual-piston architecture, it eliminates pulsation through active flow compensation—ensuring stable baseline performance, superior retention time reproducibility (<0.1% RSD), and extended column lifetime. Its robust stainless-steel fluidic path supports compatibility with common HPLC solvents—including aqueous buffers, acetonitrile, methanol, and tetrahydrofuran—within pressure limits up to 6000 psi (414 bar). The P100 integrates seamlessly with legacy and modern Thermo Fisher LC systems (e.g., SCM, SN, and SpectraSYSTEM platforms) and third-party controllers via analog or RS-232 interfaces.
Key Features
- Dual-piston design with real-time flow compensation for pulseless operation and <0.05% flow ripple
- Microprocessor-based diagnostics continuously monitor pressure, flow rate, valve timing, and motor performance
- Built-in maintenance log records operational hours, prime cycles, seal replacements, and error codes for GLP-compliant traceability
- Front-panel keypad and LCD display enable local parameter entry, status monitoring, and diagnostic mode access
- Auto-purge and auto-prime functions reduce manual intervention and improve startup consistency
- Chemically resistant wetted materials: 316 stainless steel pump heads, sapphire piston seals, and PTFE/PEEK tubing interfaces
- Refurbishment includes full fluidic path cleaning, piston seal replacement, check valve inspection, and factory-equivalent calibration verification
Sample Compatibility & Compliance
The TSP P100 is validated for use across reversed-phase, normal-phase, ion-exchange, and size-exclusion chromatography applications. It meets mechanical and electrical safety requirements per CSA C22.2 No. 61010-1 and IEC 61010-1. While not certified for GMP production environments out-of-the-box, its diagnostic logging and maintenance tracking support audit readiness under FDA 21 CFR Part 11 when deployed with compliant data acquisition software. Instrument operation complies with ISO/IEC 17025:2017 clause 6.4.7 (equipment verification) when accompanied by documented refurbishment protocols and post-refurbishment performance qualification (PQ) reports.
Software & Data Management
The P100 operates autonomously or under external control via analog voltage input (0–10 V) or RS-232 serial communication. When integrated into Thermo Fisher’s older SpectraSYSTEM software suite (e.g., PC10, PC20), it supports method-driven gradient programming, event-triggered valve switching, and real-time pressure/flow telemetry. For modern lab informatics, third-party drivers (e.g., LabVIEW, Python pySerial) enable integration into ELN/LIMS workflows. All refurbished units ship with a PQ report detailing flow accuracy (±0.5% at 1.0 mL/min), pressure stability (±5 psi over 30 min), and leak integrity testing results—archivable for internal quality records.
Applications
- Pharmaceutical QC assays requiring strict retention time reproducibility (e.g., USP monographs for dissolution or assay methods)
- Environmental analysis of pesticides and PAHs using EPA Methods 8081/8330 with C18 columns
- Food safety testing for mycotoxins and preservatives under AOAC 999.05 and ISO 14501
- Academic research labs performing method development where cost-effective, reliable pumping is critical
- Contract testing laboratories maintaining legacy instrument fleets with documented service history
FAQ
Is the TSP P100 compatible with modern Thermo Fisher Vanquish or UltiMate 3000 systems?
No—it predates digital bus architectures used in current platforms. Integration requires analog interface modules or external PLC-based control.
What documentation accompanies the refurbished unit?
Each unit ships with a Certificate of Refurbishment, PQ report, maintenance log summary, and safety compliance statement.
Can the pump be configured for gradient mixing?
No—the P100 is a single-channel isocratic pump. Gradient functionality requires pairing with a TSP SCM or SN-series low-pressure mixing module.
Does the 6-month warranty cover parts and labor globally?
Yes—warranty service is provided via SpectraLab Scientific’s authorized technical partners in North America, EU, and APAC regions.
Are replacement parts still available for long-term support?
Yes—critical spares (piston seals, check valves, gasket kits) remain in production and are stocked by Thermo Fisher’s legacy parts division under P/Ns ending in “-P100”.
