HNPM mzr-4605 Precision Micro-Gear Metering Pump

Overview

The HNPM mzr-4605 is a precision-engineered micro-annular gear metering pump designed for continuous, highly reproducible volumetric dosing of low-to-high viscosity liquids in demanding laboratory and pilot-scale industrial environments. Based on the patented rotating micro annular gear principle—where two intermeshing gears rotate within a precisely machined housing—the mzr-4605 achieves exceptional flow linearity, minimal pulsation (< ±0.5% peak-to-peak), and near-zero internal slip across its full operating range. Unlike peristaltic or piston-based systems, this positive displacement architecture delivers consistent volumetric accuracy independent of backpressure (up to 100 bar, depending on fluid and configuration), making it suitable for high-pressure liquid handling in analytical sample introduction, reagent dosing, and closed-loop process control. Its compact form factor (143 mm length) and modular design support integration into automated workstations, custom fluidic manifolds, and GLP-compliant analytical platforms.

Key Features

• Micro annular gear technology enabling low-shear, low-pulsation fluid transport—critical for shear-sensitive formulations including biopolymers, emulsions, and nanosuspensions.
• Wide operational viscosity range: validated performance from 0.3 mPa·s (methanol) up to >100,000 mPa·s (gels and pastes), without requiring mechanical recalibration.
• Electrically driven motor with digitally controlled speed regulation (0–300 rpm), supporting precise flow rate adjustment from 1 µL/h to 1.1 L/h—spanning six orders of magnitude.
• Modular thermal management system: optional electric heating module (max. 150 °C), dual-shell temperature control (–20 °C to +150 °C), and thermal insulation kits ensure stable fluid rheology during temperature-sensitive dispensing.
• Hermetic fluid path with chemically resistant materials (e.g., PTFE, sapphire, ceramic, stainless steel 1.4404/316L), compatible with aggressive solvents, acids, and UV-curable adhesives.
• Integrated sealing solutions—including air/moisture barrier fluid seals—for handling oxygen- or moisture-sensitive reagents in inert atmosphere gloveboxes or vacuum-compatible setups.

Sample Compatibility & Compliance

The mzr-4605 accommodates a broad spectrum of liquid media, including aqueous buffers, organic solvents (e.g., acetone, THF, DMF), low-volatility oils, UV-curable acrylates, silicone-based adhesives, and non-Newtonian gels. Its material compatibility aligns with ASTM D471 and ISO 1817 standards for elastomer resistance testing. When configured with appropriate wetted-path materials and documentation packages, the pump supports operation under GMP and GLP frameworks. Full audit trails, electronic signatures, and configurable user access levels are enabled when paired with the mzr-S05E control console—meeting FDA 21 CFR Part 11 requirements for regulated pharmaceutical and clinical diagnostics applications.

Software & Data Management

The mzr-4605 operates seamlessly with the HNPM mzr-S05 and mzr-S05E control consoles, offering local keypad operation, analog (0–10 V / 4–20 mA) and digital (RS-485, Modbus RTU) interface options. The mzr-S05E variant includes Ethernet connectivity, embedded web server functionality, and native OPC UA support for integration into SCADA and MES platforms. Firmware supports programmable multi-step protocols (e.g., ramped flow profiles, timed dispense cycles, pause-and-hold sequences), with real-time flow monitoring and automatic error logging. All operational parameters—including speed, cumulative volume, runtime, and thermal status—are timestamped and exportable as CSV or XML for traceability and QA reporting.

Applications

• Automated reagent delivery in HPLC, UHPLC, and LC-MS sample introduction systems.
• Precision metering of catalysts, initiators, and crosslinkers in polymer synthesis and R&D-scale reaction engineering.
• Controlled dispensing of conductive inks, dielectric pastes, and solder fluxes in printed electronics prototyping.
• Dosing of ophthalmic, dermal, and injectable formulations in pharmaceutical formulation development and stability testing.
• Continuous feed of viscous binders and slurries in battery electrode coating and ceramic tape casting lines.
• Vacuum-compatible solvent delivery in thin-film deposition (e.g., spin-coating, dip-coating) and plasma-enhanced CVD precursor injection.

FAQ

What is the maximum allowable backpressure for the mzr-4605?

Maximum continuous backpressure depends on fluid viscosity and temperature; typical ratings range from 20 bar (low-viscosity fluids) to 100 bar (high-viscosity, heated operation). Consult the technical datasheet for pressure–viscosity–temperature derating curves.
Can the mzr-4605 handle abrasive or particulate-laden fluids?

It is not recommended for suspensions containing particles >5 µm unless fitted with optional filtration and hardened gear sets. Standard configurations are optimized for homogeneous liquids.
Is the pump suitable for sterile or aseptic processing?

While the wetted path is cleanable and autoclavable (with disassembly), the mzr-4605 is not certified as SIP-capable or pre-sterilized. For aseptic applications, it must be integrated with validated sterilization protocols and upstream filtration.
How is flow calibration performed and maintained?

Volumetric calibration is traceable to national standards (e.g., PTB, NIST) via gravimetric or syringe-pump comparison methods. HNPM provides factory calibration certificates; users may perform routine verification using calibrated flow meters or timed gravimetric collection.
Does the mzr-4605 support remote start/stop and flow modulation via PLC?

Yes—via analog voltage/current input or Modbus RTU commands. The mzr-S05E console adds Ethernet/IP and OPC UA for direct integration into industrial automation architectures.