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Jiubin JB6100-B Dry/Wet Integrated Laser Particle Size Analyzer

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Brand Jiubin
Origin Shanghai, China
Model JB6100-B
Dispersion Method Dry & Wet
Instrument Type Laboratory Laser Particle Size Analyzer
Measurement Range (Wet) 0.01 µm – 2000 µm
Repeatability ≤ ±0.5%
Measurement Time 10 s

Overview

The Jiubin JB6100-B Dry/Wet Integrated Laser Particle Size Analyzer is a fully computer-controlled laboratory instrument engineered for high-precision particle size distribution (PSD) analysis of solid particulates in both dry and aqueous or organic dispersions. It operates on the fundamental principles of Mie scattering theory and employs a convergent beam Fourier transform optical configuration—widely accepted as the metrological standard for laser diffraction-based sizing in ISO 13320:2020 and ASTM E799–22. The system integrates a dual-path optical design with automatic real-time alignment verification, ensuring long-term optical stability and minimizing operator-induced variability. Unlike conventional single-mode instruments, the JB6100-B enables seamless transition between dry dispersion (via controlled air jet feeding) and wet dispersion (using integrated ultrasonic bath and peristaltic circulation), eliminating manual reconfiguration and reducing cross-contamination risk during multi-sample workflows.

Key Features

  • Automated dry/wet dispersion mode switching via software command—no hardware reassembly required
  • Real-time optical path self-calibration using embedded reference diode and position-sensitive detector array
  • Dual-mode dispersion control: dry mode utilizes programmable air pressure (0.1–0.6 MPa) and adjustable vibratory feed rate; wet mode supports variable-speed peristaltic pump (0–300 rpm) and 40 kHz ultrasonic dispersion
  • High-sensitivity detection system with 108-channel silicon photodiode array covering angular range from 0.015° to 150°
  • Robust industrial-grade chassis with electromagnetic shielding and temperature-stabilized laser module (638 nm, <5 mW output)
  • Compliant with GLP data integrity requirements: full audit trail, user access levels, electronic signature support

Sample Compatibility & Compliance

The JB6100-B accommodates a broad spectrum of sample types—including cohesive powders (e.g., nano-sized metal oxides), fragile biological aggregates (e.g., lyophilized proteins), high-density suspensions (e.g., water-coal slurry), and low-refractive-index emulsions (e.g., silicone oil-in-water). Its wet dispersion cell accepts volumes from 20 mL to 500 mL, while the dry dispersion module handles feed rates from 0.1 g/min to 5 g/min with mass-flow feedback. All measurement protocols adhere to ISO 13320 Annex A (dry dispersion guidance) and Annex B (wet dispersion guidance), and raw scattering data files are exportable in standardized .csv and .txt formats compatible with third-party statistical analysis tools. The instrument meets CE marking requirements for EMC Directive 2014/30/EU and Low Voltage Directive 2014/35/EU.

Software & Data Management

JB6100-B is operated via Jiubin Particle Analysis Suite (JPAS) v4.2—a Windows-based application supporting Windows 10/11 (64-bit). JPAS implements full 21 CFR Part 11 compliance through role-based authentication, encrypted database logging, and immutable measurement records with timestamped operator ID. Data processing includes multiple inversion algorithms (non-negative least squares, regularization with Tikhonov constraint), refractive index compensation (real/imaginary components configurable per sample), and batch reporting with customizable templates (PDF, Excel). Raw intensity data, PSD histograms (volume-, number-, and surface-weighted), D10/D50/D90 values, span, and relative width indices are automatically calculated and archived with metadata (ambient temperature, humidity, dispersant viscosity, sonication duration).

Applications

This analyzer serves critical quality control and R&D functions across regulated and industrial sectors. In pharmaceutical manufacturing, it verifies micronized API particle distribution per USP <429> and supports inhalable dry powder formulation development. Cement producers use it to monitor clinker fineness and gypsum grinding efficiency in accordance with ASTM C114. Ceramic and pigment manufacturers rely on its reproducibility for batch-to-batch consistency of zirconia, titanium dioxide, and iron oxide pigments. Additional validated applications include coal ash classification (ASTM D5108), battery cathode material (LiCoO₂, NMC) sizing, inkjet ink particle stability assessment, and nanomaterial safety screening per OECD TG 125. Each application benefits from traceable calibration using NIST-traceable polystyrene latex standards (e.g., 100 nm, 500 nm, 3 µm).

FAQ

What dispersion media are supported in wet mode?
Deionized water, ethanol, isopropanol, and other low-viscosity solvents compatible with the PTFE-lined circulation system and quartz flow cell.
Can the instrument measure sub-100 nm particles with confidence?
Yes—the 0.01 µm (10 nm) lower detection limit is achieved under optimized wet dispersion conditions using high-intensity 638 nm laser and low-noise detector electronics, validated against TEM reference materials.
Is dry dispersion suitable for heat-sensitive or electrostatic-prone samples?
Dry mode incorporates inert gas purging option and adjustable feed vibration amplitude to minimize thermal load and static accumulation; recommended for polymers, APIs, and explosives.
How is instrument performance verified over time?
Built-in daily verification routine uses internal reference scatterer; optional annual calibration with certified PSL standards (NIST SRM 1963, 1691a) ensures continued traceability.
Does the software support automated method transfer between instruments?
Yes—JPAS allows export/import of complete measurement methods (including optical parameters, dispersion settings, and analysis models) across JB6100-B units in multi-site laboratories.

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