Masterflex B/T Programmable Peristaltic Pump Model 77111-47
| Brand | Cole-Parmer |
|---|---|
| Origin | USA |
| Manufacturer Type | Authorized Distributor |
| Import Status | Imported |
| Model | 77111-47 |
| Pricing | Upon Request |
| Speed Range | 11–321 rpm |
| Speed Accuracy | ±0.3% |
| Flow Accuracy | ±0.5% |
| Viscosity Handling | up to 10,000 cP |
| Flow Resolution Options | 0.01 / 1 / 10 mL/min |
| Single Dispense Volume Range | 0.1–999 L (0.1 L increments) |
| Repeat Dispense Count | 1–99 cycles |
| Dispense Volume per Cycle | 100 mL–1000 L |
| Control Signals | 0–20 mA, 4–20 mA, 0–10 V, TTL pulse |
| IP Rating | IP56 |
| Certifications | ISO 9001:2000, CE, CUL |
| Power Supply | 190–260 V AC, 3.3 A |
| Controller Dimensions (L×W×H) | 22.9 × 27.9 × 11.4 cm |
| Pump Head Dimensions (L×W×H) | 68.6 × 40.0 × 38.4 cm |
| Standard Tubing | Tygon LFL #91, 0.9 m |
Overview
The Masterflex® B/T Programmable Peristaltic Pump Model 77111-47 is an industrial-grade, microprocessor-controlled peristaltic pumping system engineered for precision fluid handling in regulated laboratory, pilot-scale bioprocessing, and analytical instrumentation environments. Based on the fundamental principle of positive displacement via occlusion—where rotating rollers compress flexible tubing to generate flow—the pump delivers consistent, pulse-free, non-invasive fluid transfer without contact between the drive mechanism and the process fluid. Its modular architecture separates the motor-driven pump head from the digital controller via a 1.8 m shielded cable, enabling safe remote placement in biosafety cabinets, fume hoods, or hazardous area enclosures while maintaining full operational control. Designed for compatibility with a wide range of chemically resistant tubing materials—including silicone, platinum-cured silicone, and fluoropolymer-reinforced elastomers—the system supports sterile, low-shear, and particulate-free transfer of sensitive biologicals, viscous reagents (up to 10,000 cP), and aggressive solvents.
Key Features
- Independent motor-controller architecture with 1.8 m interconnect cable for spatial flexibility and operator safety
- Backlit LED display showing real-time parameters: flow rate (mL/min), rotational speed (rpm), cumulative dispensed volume (L), and remaining repeat cycles
- Bi-directional operation for forward/reverse priming, line purging, and tubing cleaning protocols
- Programmable dispensing with user-defined single-volume delivery (0.1–999 L, 0.1 L resolution) and repeat count (1–99)
- Integrated safety interlock: automatic power cutoff when pump head cover is opened
- Keyboard lock function prevents accidental parameter changes during unattended operation
- Onboard calibration memory stores correction factors for multiple tubing sizes (e.g., #87, #91), ensuring volumetric accuracy across configurations
- Multiple analog and digital input options (0–20 mA, 4–20 mA, 0–10 V, TTL pulse) for integration into PLC-controlled or SCADA-based process systems
- IP56-rated enclosure enables direct water-rinse cleaning—critical for GMP-compliant cleanroom and cell culture workflows
Sample Compatibility & Compliance
The 77111-47 accommodates standard Masterflex tubing families—including Tygon® LFL #91 (19.1 × 31.8 × 6.4 mm), #87 (12.7 × 25.4 × 6.4 mm), and high-purity platinum-cured silicone variants—each selected for specific chemical resistance, gas permeability, and extractables profiles. Tubing selection directly determines flow range (e.g., #91: 1.3–37 L/min; #87: 0.61–17.75 L/min) and dispensing precision (±2–5 mL per 100 mL cycle). The system complies with ISO 9001:2000 quality management standards and carries CE and CUL marks for electrical safety in North America and the EU. While not inherently 21 CFR Part 11 compliant, its audit-trail-capable firmware (when paired with optional data logging software) supports GLP/GMP documentation requirements when deployed with validated procedures and change-controlled configuration management.
Software & Data Management
The pump operates autonomously via front-panel programming but supports external command sequencing through industry-standard analog/digital I/O. For advanced integration, Cole-Parmer’s optional Masterflex Connect software (Windows-based) enables remote configuration, real-time telemetry streaming, and CSV export of time-stamped flow logs—including start/stop timestamps, total volume delivered, and error codes. When deployed in regulated environments, users may implement electronic signature workflows and define role-based access controls to meet ALCOA+ data integrity principles. Firmware updates are distributed via secure download channels and require manual validation prior to installation to maintain configuration traceability.
Applications
- Automated media preparation and buffer exchange in upstream bioprocessing
- Continuous feeding of viscous polymer solutions in rheology or coating applications
- Accurate reagent dosing in clinical analyzers and HPLC sample introduction modules
- Closed-system transfer of cell culture harvests under ISO Class 5 conditions
- Calibration fluid delivery in environmental monitoring instrumentation
- Lab-scale fermentation feed control with programmable nutrient pulses
FAQ
What tubing sizes are pre-calibrated in the controller memory?
The unit ships with factory-stored calibration constants for Tygon LFL #87 and #91 tubing. Additional calibrations can be performed manually using the built-in “tubing calibration” routine and stored for up to 10 custom configurations.
Can this pump be integrated into a PLC-controlled manufacturing line?
Yes—via 4–20 mA current loop or TTL pulse input, the pump accepts external start/stop commands and accepts analog setpoint signals for dynamic flow rate modulation in real time.
Is the pump suitable for sterile applications requiring SIP (steam-in-place)?
No—the pump head and motor assembly are not rated for autoclaving or SIP. Sterility must be achieved via aseptic tubing replacement and gamma-irradiated, pre-sterilized tubing kits (e.g., Masterflex BioPure® series).
How is flow accuracy verified during qualification?
Accuracy is confirmed by gravimetric testing per ASTM D1298 or ISO 5167-3 using certified balance and temperature-controlled collection vessels, with results documented against the pump’s stated ±0.5% specification at nominal operating conditions.

