Brand Bottle Top Dispenser DV-50 (5–50 mL)
| Brand | BRAND |
|---|---|
| Origin | Beijing, China |
| Distributor Type | Authorized Distributor |
| Instrument Type | Manual Bottle Top Dispenser |
| Volume Range | 5–50 mL |
| Minimum Increment | 0.2 mL |
| Accuracy | ±0.5% |
| Error Limit | ±0.1% |
| Compliance | ISO 8655-3, GLP-compliant design |
Overview
The Brand Bottle Top Dispenser DV-50 is a precision-engineered manual liquid handling device designed for repeatable, traceable, and ergonomic dispensing of reagents, solvents, and standard solutions directly from laboratory reagent bottles (typically 100–1000 mL HDPE or glass). Operating on the positive displacement principle, the DV-50 utilizes a calibrated piston-cylinder assembly driven by a dual-gear reduction mechanism to ensure consistent volumetric delivery across its full 5–50 mL range. Unlike air-displacement pipettes, this bottle-top system eliminates aerosol generation and cross-contamination risks by maintaining a closed fluid path sealed with chemically resistant PTFE and FFKM seals. Its mechanical design conforms to ISO 8655-3 requirements for piston-operated dispensers, supporting metrological traceability when used with certified calibration standards and documented verification protocols.
Key Features
- Digitally adjustable volume setting with dual-scale vernier ring—enabling precise selection of any volume between 5 and 50 mL in 0.2 mL increments
- High-precision borosilicate glass cylinder and hardened stainless-steel piston, optimized for long-term dimensional stability and low hysteresis
- Chemical resistance verified for common organic solvents (e.g., acetone, methanol, chloroform), aqueous acids/bases (pH 1–13), and halogenated compounds
- Ergonomic dual-lever handle with tactile feedback and over-travel stop—reducing operator fatigue during high-frequency dispensing tasks
- Integrated safety valve and pressure-relief vent to prevent over-pressurization during bottle pressurization or viscous liquid dispensing
- Modular construction with tool-free disassembly for cleaning, maintenance, and seal replacement—supporting routine GLP audit readiness
Sample Compatibility & Compliance
The DV-50 accommodates standard GL45 and GL32 threaded reagent bottles and supports direct mounting without adapters. It delivers reliable performance with liquids having viscosities up to 500 mPa·s (e.g., glycerol/water mixtures, 40% sucrose solutions) and vapor pressures compatible with ambient laboratory conditions. All wetted materials comply with USP Class VI and FDA 21 CFR 177.2600 specifications. The dispenser meets ISO 8655-3:2022 accuracy criteria (±0.5% full-scale error, ±0.1% repeatability under controlled temperature and humidity per Annex A), and its mechanical calibration protocol aligns with internal quality control requirements for ISO/IEC 17025-accredited laboratories.
Software & Data Management
As a fully mechanical, non-electronic instrument, the DV-50 requires no firmware, drivers, or software integration. However, its calibration and usage records are fully compatible with electronic lab notebook (ELN) systems and LIMS workflows. Users may document volume settings, calibration dates, operator IDs, and verification results using standardized templates compliant with 21 CFR Part 11 (when implemented with appropriate access controls and audit trails). Optional calibration certificates—traceable to NIM (National Institute of Metrology, China) or DAkkS-accredited reference standards—are available upon request to support regulatory submissions and internal SOP validation.
Applications
- Preparation of calibration standards and QC reference solutions in analytical chemistry labs (ICP-MS, HPLC, titration)
- Accurate dosing of hazardous or volatile reagents (e.g., concentrated HNO₃, THF, DMF) in fume hood environments
- Formulation of culture media and buffer stock solutions in microbiology and cell biology workflows
- Serial dilution series generation where intermediate volumes (e.g., 12.4 mL, 37.8 mL) must be reproducibly dispensed without recalibration
- Supporting ISO/IEC 17025 method validation studies requiring documented volumetric uncertainty budgets
FAQ
What is the recommended calibration frequency for the DV-50 in a GLP environment?
Calibration should be performed before first use, after any maintenance or seal replacement, and at defined intervals (e.g., daily pre-use check, weekly full verification) per laboratory SOP—aligned with ISO/IEC 17025 clause 6.4.3.
Can the DV-50 be used with hydrofluoric acid (HF) or strong oxidizers like perchloric acid?
No. While PTFE/FFKM seals resist many aggressive chemicals, HF attacks glass components, and perchloric acid poses explosion risks under pressurized dispensing conditions—consult BRAND’s chemical compatibility chart prior to use.
Is the 0.1% error specification valid across the entire 5–50 mL range?
The ±0.1% figure refers to relative standard deviation (RSD) under repeatability testing at mid-range (e.g., 25 mL); absolute error remains within ±0.5% of set volume per ISO 8655-3 tolerance limits.
Does the DV-50 require periodic lubrication of the piston?
No. The piston-cylinder interface uses dry-running, self-lubricating polymer composites; adding external lubricants may compromise seal integrity and accuracy.
How is traceability maintained when using multiple DV-50 units across different shifts?
Each unit carries a unique serial number engraved on the housing; calibration logs, usage history, and maintenance records must be linked to that identifier in accordance with ALCOA+ data integrity principles.
