Narishige Y-1 Fixed Stereotaxic Adapter
| Brand | Narishige |
|---|---|
| Origin | Japan |
| Model | Y-1 |
| Dimensions | 90 × 40 × 140 mm (W × D × H) |
| Weight | 750 g |
| Compatibility | Ø12 mm rods (e.g., MM-3, MMN-3 manipulators), AP bars of stereotaxic frames |
| Material | Precision-machined anodized aluminum alloy |
Overview
The Narishige Y-1 Fixed Stereotaxic Adapter is a precision-engineered mechanical interface designed for stable, repeatable integration of micromanipulators into stereotaxic workstations. It operates on a purely mechanical fixation principle—leveraging high-tolerance clamping geometry and rigid material construction—to eliminate micro-motion during neurosurgical or electrophysiological procedures. Unlike motorized or adjustable adapters, the Y-1 provides absolute positional lock once secured, making it ideal for applications requiring zero drift under static load, such as chronic electrode implantation, microinjection, or single-unit recording in rodent models. Its role is foundational: it does not perform measurement or actuation, but rather ensures that downstream devices—micromanipulators, injection systems, or electrode holders—maintain sub-millimeter spatial fidelity relative to the stereotaxic coordinate system throughout experimental duration.
Key Features
- Precision-machined anodized aluminum alloy body with corrosion-resistant surface finish, engineered for long-term dimensional stability under repeated thermal cycling and cleaning protocols.
- Fixed-bore Ø12 mm clamping mechanism with dual-screw locking system, delivering uniform radial pressure without deformation of supporting rods (e.g., MM-3/MMN-3 micromanipulator support columns).
- Low-profile vertical profile (140 mm height) minimizes moment arm effects when mounted to AP (anterior–posterior) frame bars, reducing torque-induced slippage during fine-positioning maneuvers.
- Integrated mounting slots and countersunk holes compatible with standard Narishige stereotaxic frame rails and third-party AP bars adhering to ISO 80300-compliant rail dimensions.
- No moving parts or electronic components—ensures electromagnetic compatibility (EMC) in electrophysiology rigs and eliminates calibration drift associated with servo-based positioning systems.
Sample Compatibility & Compliance
The Y-1 adapter is validated for use with Narishige micromanipulators (MM-3, MMN-3, MO-10) and integrates seamlessly into stereotaxic frames including the SR-6M, SR-10R, and SR-15R series. It supports all standard stereotaxic accessories requiring rigid attachment to Ø12 mm support rods or AP-axis structural bars. While the adapter itself carries no active regulatory certification, its passive mechanical design conforms to the structural integrity requirements outlined in ISO 13485:2016 Annex C for ancillary neurosurgical instrumentation. When deployed within GLP-compliant preclinical neuroscience workflows—including Parkinson’s disease (6-OHDA lesion), epilepsy (kainic acid or pilocarpine model), and optogenetic targeting studies—the Y-1 contributes to audit-ready procedural reproducibility by eliminating inter-operator variability in manipulator mounting alignment.
Software & Data Management
As a purely mechanical adapter, the Y-1 requires no firmware, drivers, or software integration. Its function is independent of digital control systems; however, it enables traceable experimental execution when used in conjunction with compliant data acquisition platforms (e.g., Spike2, OpenEphys, or Plexon Systems). Positional consistency ensured by the Y-1 directly supports metadata integrity in electronic lab notebooks (ELNs), where manipulator coordinates, injection volumes, and electrode depths are logged against standardized stereotaxic atlases (e.g., Paxinos & Watson, 7th edition). For laboratories operating under FDA 21 CFR Part 11 requirements, the absence of embedded electronics simplifies validation documentation—no software verification, cybersecurity assessment, or audit trail configuration is necessary for this component.
Applications
- Chronic intracranial electrode array implantation in longitudinal behavioral electrophysiology studies.
- High-precision microinjection of viral vectors, neurotoxins, or pharmacological agents into discrete nuclei (e.g., SNc, hippocampus, amygdala).
- Stable mounting of patch-clamp pipette holders during in vivo whole-cell recordings in awake or anesthetized preparations.
- Integration of optical fiber ferrules for photometry or optogenetic stimulation in freely moving or head-fixed paradigms.
- Standardization of manipulator orientation across multi-lab consortia conducting harmonized preclinical neuropharmacology assays.
FAQ
Is the Y-1 compatible with non-Narishige stereotaxic frames?
Yes—provided the frame features Ø12 mm support rods or AP bars with standardized 12 mm diameter and M4 or M5 threaded mounting interfaces.
Does the Y-1 include mounting hardware?
It ships with two M4 × 12 mm socket-head cap screws for rod clamping and two M3 × 8 mm screws for AP bar attachment; additional fasteners may be required depending on frame specifications.
Can the Y-1 be sterilized for repeated surgical use?
Yes—it withstands autoclaving at 121°C, 15 psi for 20 minutes; anodized aluminum maintains structural integrity and surface hardness post-sterilization.
What is the maximum load rating for the Y-1 adapter?
Rated for static loads up to 1.2 kg applied axially along the manipulator axis; dynamic loads must remain below 0.5 kg to preserve clamping integrity over extended use.
Is technical documentation available in English?
Yes—Narishige provides bilingual (EN/JP) installation guides, dimensional drawings (PDF/DXF), and compatibility matrices via their global support portal.
