DHS NX-1R Ultra-Quiet High-Speed Refrigerated Centrifuge
| Brand | DHS |
|---|---|
| Origin | Beijing, China |
| Model | NX-1R |
| Instrument Type | Benchtop Centrifuge |
| Speed Range | High-Speed (10,000–30,000 rpm) |
| Cooling Function | Refrigerated |
| Configuration | Fixed-Angle Rotor Centrifuge |
| Separation Class | Biomacromolecules |
| Maximum Capacity | 12 × 5 mL |
| Maximum Speed | 17,500 rpm |
| Maximum RCF | 23,300 × g |
| Dimensions (W × D × H) | 270 × 355 × 550 mm |
| Noise Level | <50 dB(A) at Max Speed |
| Minimum Temperature | ≤−20 °C |
| Cooling Rate | From RT to 0 °C in <10 min |
| Operating Temp Stability | Maintains ≤4 °C during high-speed runs |
Overview
The DHS NX-1R is a benchtop ultra-quiet high-speed refrigerated centrifuge engineered for precision biomacromolecule separation in demanding laboratory environments. It operates on the principle of sedimentation under controlled gravitational force (RCF), where rotational motion generates centrifugal acceleration to separate particles based on density, size, and shape in liquid suspensions. Designed specifically for applications requiring thermal stability—such as nucleic acid purification, protein isolation, viral pellet recovery, and subcellular fractionation—the NX-1R integrates advanced vapor-compression refrigeration with optimized rotor dynamics to maintain sample integrity across extended high-speed runs. Its compact footprint and robust thermal management enable consistent operation at ≤4 °C even at 17,500 rpm, meeting critical requirements for temperature-sensitive biological workflows.
Key Features
- Ultra-low noise operation: Acoustic output <50 dB(A) at maximum speed, achieved via precision-balanced rotor assembly, vibration-dampening chassis mount, and aerodynamically optimized airflow ducting—ideal for open-lab or shared core facility settings.
- High-efficiency refrigeration system: Dual-stage compressor architecture enables rapid cooling from ambient to 0 °C in under 10 minutes and sustained operation down to −20 °C, with active condensate management to prevent frost accumulation in the chamber.
- Enhanced safety and durability: All-metal housing with electrostatically applied baked enamel finish resists chemical exposure and facilitates decontamination; integrated UV-compatible silicone gasketing allows full-unit sterilization under standard laboratory UV protocols.
- Intelligent operational controls: Dedicated “quick-spin” button for transient centrifugation without parameter reconfiguration; electronic lid interlock ensures rotor engagement verification prior to acceleration; real-time monitoring of temperature, speed, and RCF with automatic shutdown on overtemperature or overspeed events.
- Corrosion-resistant cold chamber: Internally coated stainless steel cavity with hydrophobic surface treatment minimizes condensation adhesion and inhibits microbial growth—critical for long-term reliability in humid or high-use environments.
Sample Compatibility & Compliance
The NX-1R supports fixed-angle rotors compatible with standard 0.2–5 mL conical-bottom tubes, including polypropylene, polycarbonate, and ultracentrifuge-grade materials. Its 12 × 5 mL capacity configuration accommodates common microcentrifuge tube formats used in molecular biology, clinical diagnostics, and bioprocessing QC labs. The instrument complies with IEC 61010-1:2010 for electrical safety and IEC 61000-6-3:2019 for electromagnetic compatibility. While not certified for ISO 13485 or FDA 21 CFR Part 11 out-of-the-box, its audit-ready operational logs, password-protected parameter locking, and time-stamped run records support GLP/GMP-aligned documentation practices when deployed within validated laboratory systems.
Software & Data Management
The NX-1R features an embedded microcontroller-based interface with non-volatile memory for storing up to 99 user-defined protocols. Each run record includes timestamped metadata: start/stop time, final RCF, average temperature, total runtime, and rotor identification. Export is supported via USB port to CSV format for integration into LIMS or ELN platforms. Firmware updates are performed offline using signed binary files to ensure traceability and system integrity—consistent with data governance expectations in regulated environments.
Applications
- Purification of plasmid DNA, genomic DNA, and RNA from bacterial lysates or mammalian cell cultures.
- Isolation of extracellular vesicles (exosomes) and ribonucleoprotein complexes (RNPs) requiring low-temperature stabilization.
- Preparative pelleting of mitochondria, nuclei, and membrane fractions in cell fractionation workflows.
- Routine quality control of recombinant proteins, monoclonal antibodies, and vaccine intermediates where thermal denaturation must be avoided.
- High-throughput sample preparation for next-generation sequencing library construction and mass spectrometry analysis.
FAQ
What is the minimum operating temperature, and how quickly does the chamber reach it?
The NX-1R achieves ≤−20 °C under no-load conditions. From ambient (25 °C) to 0 °C, cooling is completed in less than 10 minutes.
Does the instrument support rotor auto-recognition?
No—rotor identification is manual via the control interface; users must select the installed rotor type before initiating a protocol.
Can the NX-1R be used for clinical diagnostic sample processing under CLIA or CAP guidelines?
Yes—when operated within a documented SOP, with routine preventive maintenance and calibration tracking, the NX-1R meets foundational instrumentation requirements for clinical lab use.
Is the refrigeration system serviceable in the field?
Compressor and refrigerant circuit servicing requires authorized DHS technical personnel; however, filter replacement and chamber cleaning are user-performed maintenance tasks.
Are third-party rotors compatible with the NX-1R?
Only DHS-certified rotors are supported; use of non-OEM rotors voids warranty and may compromise safety interlocks and thermal performance.
