Agilent 7700 Series ICP-MS (Refurbished)
| Brand | Agilent Technologies |
|---|---|
| Origin | USA |
| Model | 7700x / 7700s |
| Instrument Type | Inductively Coupled Plasma Mass Spectrometer |
| Year of Manufacture | ~2013–2014 |
| Operational Age | 3–4 years |
| Warranty | 12 months |
| Mass Range | 2–260 amu |
| Detection Limits | Be(9) 0.5 ppt, In(115) 0.1 ppt, Bi(209) 0.1 ppt |
| Sensitivity | Li(7) 50 Mcps/ppm (7700x), Y(89) 60 Mcps/ppm (7700x) / 240 Mcps/ppm (7700s), Tl(205) 80 Mcps/ppm (7700x) / 120 Mcps/ppm (7700s) |
| Oxide Ratio CeO⁺/Ce⁺ | ≤1.5% (7700x), ≤3.0% (7700s) |
| Doubly Charged Ratio Ce²⁺/Ce⁺ | ≤3.0% |
| Isotopic Ratio Precision (¹⁰⁷Ag/¹⁰⁹Ag) | RSD ≤0.1% |
| Abundance Sensitivity | 5×10⁻⁷ (low-mass end), 1×10⁻⁷ (high-mass end) |
| Collision/Reaction Cell | Third-generation ORS3 with He-only collision mode |
| RF Generator | Digital frequency-controlled ICP source |
| Sample Introduction | Compatible with standard nebulizers, microflow systems, laser ablation, and high-matrix introduction (HMI capable up to 3% TDS) |
| Software Platform | MassHunter Workstation (v10.x or later, fully licensed) |
Overview
The Agilent 7700 Series ICP-MS is a compact, high-performance inductively coupled plasma mass spectrometer engineered for ultra-trace elemental and isotopic analysis across diverse sample matrices. As the successor to the widely adopted 7500 series, the 7700 platform integrates critical hardware innovations—including a digitally controlled RF generator, third-generation octopole reaction system (ORS3), and optimized ion optics—to deliver enhanced sensitivity, reduced polyatomic interferences, and superior robustness in high-salt and organic solvent environments. This refurbished unit retains full factory-specification performance and has undergone comprehensive functional validation, including mass calibration, sensitivity verification, oxide/doubly charged ion assessment, and background stability testing. Its compact footprint (the smallest commercial ICP-MS at time of original release) makes it ideal for laboratories with constrained bench space without compromising analytical capability.
Key Features
- Digital RF Generator: Enables precise, real-time impedance matching and stable plasma operation—even during transient sample introduction (e.g., LC-ICP-MS, laser ablation) or with high-TDS (>3%) or organic-rich (e.g., 100% methanol) solutions—without torch extinction.
- Third-Generation ORS3 Collision/Reaction Cell: Operates exclusively in helium collision mode to suppress >99.9% of common polyatomic interferences (e.g., 40Ar16O⁺ on 56Fe⁺, 40Ar40Ar⁺ on 80Se⁺) without requiring reactive gases or complex method optimization.
- High Matrix Introduction (HMI) Capability: Engineered with advanced interface design and ion lens tuning to maintain signal stability and minimize cone clogging when analyzing seawater, brines, geological digests, and biological fluids containing >3% total dissolved solids.
- MassHunter Software Integration: Fully licensed MassHunter Workstation v10.x or later supports automated QA/QC workflows, real-time drift correction, isotope ratio calculation, spectral interference diagnostics, and 21 CFR Part 11-compliant audit trails for regulated environments.
- Modular Architecture: Supports seamless coupling with HPLC, GC, CE, and laser ablation systems via standardized interfaces; includes dedicated drivers for Agilent’s 1260/1290 Infinity LC platforms and NWR laser ablation systems.
Sample Compatibility & Compliance
The Agilent 7700 Series accommodates aqueous acids (HNO₃, HCl, HF), organic solvents (methanol, ethanol, IPA), and high-salinity matrices (seawater, brine, soil extracts) without hardware modification. It complies with ASTM D5673 (trace metals in water), ISO 17294-2 (water quality—elemental specifications), and USP / (elemental impurities in pharmaceuticals). All refurbished units undergo GLP-aligned qualification: installation qualification (IQ), operational qualification (OQ), and performance qualification (PQ) per Agilent’s original protocols. Documentation includes full PQ reports, calibration certificates traceable to NIST SRMs, and a validated instrument logbook covering maintenance history and detector aging metrics.
Software & Data Management
Equipped with MassHunter Workstation software (fully activated license included), the system supports method-driven acquisition, automated internal standard correction, multi-isotope dilution quantitation (IDMS), and real-time QC flagging (e.g., sensitivity drop >15%, oxide ratio drift >0.5%). Raw data files (.d format) are stored in vendor-neutral, ASCII-exportable formats compatible with LIMS integration. Audit trail functionality meets FDA 21 CFR Part 11 requirements, including electronic signatures, user access controls, and immutable record retention. Optional add-ons include MassHunter Quantitative Analysis, MassHunter Isotope Ratio Analysis, and MassHunter BioConfirm for metallomics applications.
Applications
- Environmental monitoring: Ultra-trace heavy metal speciation (Pb, Cd, As, Hg) in drinking water per EPA Method 6020B and ISO 17294-2.
- Geochemistry: High-precision isotope ratio measurements (e.g., Sr, Nd, Hf) in rock digests using MC-ICP-MS–compatible protocols.
- Pharmaceuticals: Elemental impurity screening per ICH Q3D guidelines, including catalyst residue analysis (Pd, Pt, Rh) in APIs.
- Semiconductor manufacturing: Sub-ppt detection of metallic contaminants (Na, K, Fe, Cu) in ultrapure water and photoresists (7700s variant optimized for this use case).
- Clinical research: Multi-element biomonitoring (Zn, Se, Cu, Mo) in serum and urine with matrix-matched calibration and internal standardization.
FAQ
Is this unit covered by Agilent’s original factory warranty?
No—the unit carries a 12-month comprehensive parts-and-labor warranty administered directly by our ISO 9001-certified service team, including remote diagnostics, on-site support, and priority spare parts fulfillment.
Does the refurbishment include detector replacement?
Yes—all refurbished 7700 systems undergo electron multiplier (EM) and/or discrete dynode detector replacement based on usage logs and gain testing; detector age is documented in the PQ report.
Can the instrument be validated for GMP/GLP compliance?
Yes—we provide IQ/OQ/PQ documentation packages aligned with ASTM E2500, ISO/IEC 17025, and FDA guidance; optional third-party certification available upon request.
What consumables are included with delivery?
Standard kit includes one set of Ni sampler/skimmer cones, PFA nebulizer, Scott-type spray chamber, quartz torch, and 100 hours of MassHunter software support.
Is training provided for operators and maintenance personnel?
Yes—two days of on-site application and preventive maintenance training are included, delivered by Agilent-certified engineers with ≥10 years’ field experience on 7500/7700 platforms.
