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Beijing Saite Technology SFT-130A-E Fully Automated Supercritical Fluid Extractor

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Brand Saite Technology (STKJ)
Origin Beijing, China
Manufacturer Type Authorized Distributor
Country of Origin China
Model SFT-130A-E
Maximum Temperature 200 °C
Extraction Vessel Volumes 100 mL, 250 mL, 500 mL, 1000 mL
Maximum Operating Pressure 48.3 MPa (7,000 psi)
CO₂ Flow Rate Range Up to 500 mL/min (liquid CO₂ equivalent)

Overview

The Beijing Saite Technology SFT-130A-E Fully Automated Supercritical Fluid Extractor is an engineered platform for precision supercritical fluid extraction (SFE) using carbon dioxide (CO₂) as the primary solvent. It operates on the principle that above its critical point (31.1 °C, 7.38 MPa), CO₂ exhibits tunable solvation power—density and polarity can be modulated via controlled pressure and temperature adjustments. This enables selective, solvent-free extraction of thermolabile, non-polar to moderately polar compounds including essential oils, lipids, alkaloids, cannabinoids, and natural antioxidants. Designed for reproducible method development and scale-up validation, the SFT-130A-E supports both analytical-scale optimization and preparative extraction workflows in compliance with ISO 17025–accredited laboratories.

Key Features

  • Fully automated operation with integrated PLC-based control system enabling unattended execution of multi-step extraction protocols—including pre-pressurization, static/dynamic extraction, pressure ramping, and post-extraction depressurization.
  • Remote monitoring and control via Ethernet-enabled HMI interface; compatible with secure LAN/WAN access for real-time parameter adjustment and alarm logging.
  • Programmable extraction sequences with up to 99 user-defined steps, each configurable for temperature setpoint, pressure target, CO₂ flow rate, static dwell time, and dynamic extraction duration.
  • Robust stainless-steel construction (316 SS) for all high-pressure wetted parts, rated to 48.3 MPa (7,000 psi) and 200 °C—validated per ASME B31.3 process piping standards.
  • Modular vessel configuration supporting interchangeable extraction cells (100 mL, 250 mL, 500 mL, and 1000 mL) to accommodate sample mass ranging from 1 g to 250 g without hardware modification.
  • Integrated CO₂ mass flow controller with thermal dispersion sensing, calibrated for liquid CO₂ delivery up to 500 mL/min at standard conditions (0 °C, 1 atm), ensuring stoichiometric consistency across replicates.

Sample Compatibility & Compliance

The SFT-130A-E accommodates solid, semi-solid, and powdered matrices—including plant biomass, foodstuffs, pharmaceutical intermediates, and polymer composites—without requiring derivatization or organic solvent pre-treatment. Its closed-loop CO₂ recirculation option minimizes environmental impact and operational cost. The system meets mechanical integrity requirements under PED 2014/68/EU (Category IV pressure equipment) and complies with local Chinese GB/T 150.1–2011 pressure vessel design codes. While not certified for GMP manufacturing environments, it supports GLP-compliant documentation through audit-trail-enabled software (see Software & Data Management). Method transfer aligns with ASTM D7923–21 (Standard Guide for Supercritical Fluid Extraction of Natural Products) and supports validation per ICH Q2(R2) for analytical method robustness assessment.

Software & Data Management

The proprietary STKJ-SFE Control Suite provides a Windows-based GUI with dual-mode operation: manual override and sequence-driven automation. All process parameters—including real-time pressure, temperature, flow, and elapsed time—are logged at 1 Hz resolution with automatic timestamping and user ID tagging. Raw data exports to CSV or HDF5 format; metadata conforms to ISA-88 batch record structure for traceability. Audit trails are immutable and password-protected, satisfying FDA 21 CFR Part 11 requirements for electronic records and signatures when deployed on validated IT infrastructure. Optional integration with LIMS via OPC UA enables automated result ingestion into enterprise quality databases.

Applications

  • Isolation of volatile oils from citrus peels, lavender, and peppermint for fragrance and flavor industries.
  • Decaffeination of green coffee beans and tea leaves while preserving chlorogenic acids and catechins.
  • Extraction of omega-3 fatty acids from fish oil and algal biomass with minimal oxidation.
  • Purification of botanical actives (e.g., curcumin, resveratrol, paclitaxel precursors) for preclinical formulation studies.
  • Residual solvent removal from pharmaceutical granules and medical device coatings.
  • Decontamination of microplastics and persistent organic pollutants (POPs) from environmental sediment samples prior to GC–MS analysis.

FAQ

What solvents are compatible with the SFT-130A-E besides CO₂?

The system is optimized for CO₂ as the primary supercritical fluid. Co-solvents such as ethanol, methanol, or water may be introduced via auxiliary injection modules (sold separately) at concentrations ≤15% v/v.
Does the system include a CO₂ recycling unit?

A closed-loop CO₂ recovery module is available as an optional add-on, achieving >90% solvent reuse efficiency and reducing operating costs by up to 65% over open-loop operation.
Can extraction methods be exported and shared between instruments?

Yes—method files (.sfe) are portable across SFT-130A-E units running firmware v3.2 or higher and retain full parameter fidelity, including safety interlock configurations.
What maintenance intervals are recommended for high-pressure seals and valves?

O-rings in the extraction cell and back-pressure regulator should be inspected every 200 operating hours and replaced every 500 hours or after exposure to abrasive particulates.
Is third-party calibration certification available?

NIST-traceable calibration certificates for pressure transducers and PT100 temperature sensors are provided upon request, with annual recalibration services supported through authorized STKJ service centers in Asia and Europe.

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