Masterflex® C/L® Adjustable-Speed Peristaltic Pump Model 77122-00

Overview

The Masterflex® C/L® Adjustable-Speed Peristaltic Pump Model 77122-00 is a precision-engineered, single-channel peristaltic pump designed for accurate, pulse-free fluid delivery in demanding laboratory, analytical, and industrial process applications. Utilizing the fundamental principle of peristalsis—where rollers compress flexible tubing to generate flow—the C/L® series delivers consistent, non-invasive fluid handling without contamination risk or valve wear. Its compact 1/4-DIN footprint enables seamless integration into control panels, analytical instrumentation racks, and OEM systems. The pump operates bidirectionally and supports remote start/stop via dry-contact signaling, making it suitable for automated workflows requiring synchronization with PLCs or data acquisition systems. Engineered for long-term reliability, the pump head features stainless steel rollers and a chemically resistant housing composed of polyphenylene sulfide (PPS) and acetal copolymer—ensuring dimensional stability under thermal cycling and exposure to moderate solvents.

Key Features

• Single-channel configuration with reversible rotation and precise speed control via analog input or front-panel keypad
• Flow range: 0.002–43 mL/min (dependent on tubing inner diameter and motor speed; calibrated per ISO 8503-2 guidelines for volumetric accuracy)
• 1/4-DIN panel-mount design (96 mm × 96 mm faceplate) optimized for space-constrained environments
• Stainless steel rollers and PPS/acetal pump head provide mechanical robustness and resistance to hydrolysis, oxidation, and UV degradation
• Factory-calibrated speed range: 0.1–60 rpm, offering fine resolution for low-flow applications such as reagent dosing, cell culture media perfusion, or HPLC mobile phase delivery
• Included standard tubing: 1.5 m length of Tygon® E-LFL (0.89 mm ID), certified to USP Class VI and FDA 21 CFR 177.2600 for biocompatibility and extractables control
• Dry-contact remote interface (NO/NC) compatible with TTL, 24 VDC, or relay-based control architectures

Sample Compatibility & Compliance

The C/L® pump is inherently compatible with a broad spectrum of fluids—including aqueous buffers, organic solvents, acids, bases, and biological suspensions—provided appropriate tubing is selected. Tubing material selection follows established chemical compatibility matrices (per Cole-Parmer’s Chemical Resistance Guide v.4.2) and regulatory requirements. Platinum-cured silicone, C-Flex®, Pharmed® BPT, Tygon® 3603/E-LFL, and Viton® fluorocarbon tubing options are available in ID sizes from 0.19 mm to 2.79 mm, each validated for specific use cases: Pharmed® BPT meets USP Class VI and EP 3.2.9 standards for pharmaceutical manufacturing; Tygon® E-LFL complies with FDA 21 CFR 177.2600 and NSF/ANSI Standard 51 for food contact; Viton® tubing provides extended service life in aggressive media including chlorinated hydrocarbons and aromatic solvents. All configurations support GLP/GMP traceability when paired with audit-trail-capable controllers and calibrated flow verification protocols.

Software & Data Management

While the Model 77122-00 operates as a standalone analog-controlled device, it is fully compatible with Masterflex® SmartControl™ digital interfaces (e.g., Model 77400-10) for RS-485 Modbus RTU communication, real-time speed monitoring, and event logging. When integrated into validated systems, the pump supports 21 CFR Part 11-compliant electronic records through third-party SCADA or LIMS platforms that enforce user authentication, electronic signatures, and immutable audit trails. Flow calibration certificates (traceable to NIST standards) and tubing lifetime logs—based on cumulative revolutions and chemical exposure history—can be maintained per ISO/IEC 17025 quality management requirements.

Applications

• Continuous sampling in environmental water analysis (EPA Method 300.0, ASTM D511)
• Reagent metering in clinical chemistry analyzers and immunoassay platforms
• Perfusion of 3D bioreactors and microfluidic organ-on-chip systems
• Controlled addition of catalysts or initiators in polymer synthesis
• Low-shear transfer of shear-sensitive biologics (e.g., viral vectors, exosomes)
• OEM integration into CE-marked IVD instruments and ISO 13485-certified manufacturing lines

FAQ

What tubing materials are recommended for pharmaceutical-grade fluid transfer?
Pharmed® BPT tubing is the preferred choice for USP , , and EU GMP Annex 1-compliant applications due to its low extractables profile, thermal stability up to 135°C, and validation documentation package.
Can this pump be used in explosion-proof environments?
No—Model 77122-00 is not intrinsically safe or ATEX-certified. For hazardous locations, consult Masterflex® Ex-rated drive systems (e.g., Model 77400-EX) with appropriate barrier-protected motor enclosures.
How is flow accuracy verified during qualification?
Flow verification follows ASTM D3417-20 Annex A1 using gravimetric measurement over ≥3-minute intervals at three speed points (10%, 50%, 90% max rpm), with uncertainty ≤±2.5% of reading (k=2) when using certified tubing.
Is firmware upgrade capability supported?
Firmware updates are not applicable—the 77122-00 uses discrete analog circuitry. Digital control upgrades require pairing with SmartControl™ or equivalent external drive modules.
What is the expected operational lifetime of Tygon® E-LFL tubing at 30 rpm?
Under continuous operation with deionized water at ambient temperature, Tygon® E-LFL (0.89 mm ID) demonstrates >1,500 hours of service life before fatigue-induced leakage, per accelerated aging tests per ISO 10993-5 cytotoxicity protocols.