Masterflex I/P Digital Brushless Programmable Peristaltic Pump Model 77964-00

Overview

The Masterflex I/P Digital Brushless Programmable Peristaltic Pump Model 77964-00 is an industrial-grade, microprocessor-controlled peristaltic pumping system engineered for precision fluid handling in regulated laboratory, pilot-scale bioprocessing, and continuous manufacturing environments. Utilizing the fundamental principle of positive displacement via roller compression of flexible tubing—commonly referred to as the “peristaltic” mechanism—the pump achieves contamination-free transfer without exposing internal components to the process fluid. Its brushless DC motor eliminates carbon brush wear, ensuring long-term speed stability and eliminating routine maintenance associated with brushed motors. Designed to meet stringent environmental demands, the unit complies with IP66 and NEMA 4X specifications, enabling direct washdown with water or disinfectant solutions—a critical requirement for clean-in-place (CIP) protocols in pharmaceutical, food & beverage, and clinical diagnostics applications.

Key Features

• Sealed, full-keyboard membrane interface with LED display showing real-time parameters: flow rate (mL/min), rotational speed (rpm), dispensed volume (mL), cumulative volume (mL), tube ID, direction of rotation, operating mode, remote input status, and active calibration settings.
• Non-volatile memory retains calibrated flow coefficients for one selected tube size—even after power loss—ensuring measurement continuity across operational sessions.
• Bidirectional operation supports forward/reverse pumping sequences, facilitating tube priming, backflushing, and residual clearance prior to sample changeover.
• Programmable dispensing logic: single-volume delivery (10 mL to 26,520 L, 1 mL increments), repeat cycles (1–999,999), and time-based run duration (1–999,999 seconds).
• Robust 316 stainless steel housing and fully sealed electronics withstand exposure to aggressive solvents, caustics, and oxidizing agents common in chemical synthesis and wastewater treatment workflows.
• Support for dual-head configuration (via optional Y-connector or parallel routing) enables either simultaneous multi-stream delivery or doubled volumetric throughput—subject to mechanical synchronization and tube compatibility constraints.

Sample Compatibility & Compliance

The pump accommodates a wide range of chemically resistant tubing materials certified for use in GxP environments, including Masterflex Platinum-Cured Silicone, Bio-Platinum Silicone, Enhanced Bio-Platinum Silicone, and Tygon® LFL formulations (e.g., part numbers 06429-73, 06429-88). Tubing selection directly governs maximum flow capacity, pressure tolerance, and particulate shedding characteristics—critical considerations for sterile filtration, cell culture media transfer, and chromatography mobile phase delivery. The system meets CE and CUL safety standards and is manufactured under an ISO 9001:2000 quality management system. While not inherently 21 CFR Part 11 compliant, its digital control architecture supports integration into validated systems when paired with audit-trail-capable SCADA or LIMS platforms.

Software & Data Management

The I/P series operates as a standalone instrument with no embedded PC or proprietary software dependency. All configuration and operation occur via front-panel controls or analog input signals (0–20 mA, 4–20 mA, 0–10 V), enabling seamless integration into existing PLC-driven automation frameworks. The absence of USB or Ethernet interfaces precludes native data logging; however, external acquisition systems may record analog output signals corresponding to speed or flow. For laboratories requiring electronic records, third-party data loggers or programmable logic controllers can capture timestamps, setpoints, and status flags—including error codes displayed during fault conditions (e.g., motor stall, tube occlusion, or overtemperature).

Applications

• Pharmaceutical manufacturing: Accurate metering of buffers, excipients, and API solutions during formulation and fill-finish operations.
• Biotechnology: Sterile transfer of cell culture media, harvest streams, and purification buffers in upstream and downstream processing skids.
• Environmental testing labs: Automated sampling and reagent addition in continuous water quality monitoring stations.
• Academic research: Controlled dosing in microfluidic experiments, enzymatic assays, and reaction kinetics studies where fluid isolation is mandatory.
• Food & beverage QC: Precise ingredient dosing during sensory panel preparation or shelf-life stability trials.

FAQ

What tubing sizes are supported by the 77964-00 and 77964-10 configurations?
The 77964-00 includes the Easy-Load pump head (77601-10) optimized for smaller-diameter tubes such as #26, #73, and #82. The 77964-10 integrates the high-flow pump head (77600-62), compatible with thicker-walled tubes (#70, #88, #89) to support higher volumetric throughput.
Can this pump be integrated into a GMP-compliant production line?
Yes—when deployed with appropriate tubing qualification, calibration documentation, and procedural controls, the I/P pump satisfies functional requirements for fluid transfer in GMP environments. Validation must include flow accuracy verification across the intended operating range and tubing lot.
Is remote start/stop functionality available without custom wiring?
Yes—standard analog inputs (0–10 V, 4–20 mA) allow direct connection to PLC outputs or footswitches (e.g., part 07595-43) without additional interface modules.
Does the pump retain calibration data after power interruption?
Yes—calibration coefficients are stored in non-volatile memory and persist through power cycling, ensuring consistent volumetric performance across operational shifts.
What is the maximum allowable backpressure for continuous operation?
Maximum recommended backpressure depends on tubing material, wall thickness, and temperature; typical limits range from 30 to 60 psi (2.1–4.1 bar) for Tygon LFL and platinum-cured silicone at 25°C. Consult Masterflex technical bulletins for pressure derating curves.