Masterflex L/S Precision Peristaltic Pump Model 07528-30

Overview

The Masterflex L/S Precision Peristaltic Pump Model 07528-30 is a high-reliability, digitally controlled peristaltic drive engineered for demanding laboratory, pilot-scale, and industrial fluid handling applications. Based on the proven Cole-Parmer L/S (Liquid-Solid) platform, this drive utilizes positive displacement via occlusion—where rollers compress flexible tubing against a curved housing—to deliver pulse-free, contamination-free flow without valving or seals. Its core design eliminates fluid contact with mechanical components, ensuring chemical compatibility, sterility maintenance, and minimal risk of cross-contamination—critical in pharmaceutical process development, bioprocessing, environmental sampling, and analytical reagent delivery. The 07528-30 variant supports up to four independently mountable pump heads, enabling scalable multi-channel operation while retaining individual speed control and operational integrity per channel.

Key Features

• High-precision speed control with ±0.25% accuracy across the full 1–600 rpm range—validated at critical setpoints (e.g., 0.1 rpm tolerance at 100 rpm; 1 rpm at 600 rpm)
• Reversible DC motor with forward/reverse selection via front-panel membrane keypad—enabling pre- and post-pumping tubing purge, bidirectional recirculation, or backflush protocols
• Modular architecture supporting up to four pump heads simultaneously—compatible with Standard, Easy-Load®, Easy-Load II®, Easy-Load 3®, High-Performance, Cartridge, Multichannel (2–32 channels), PTFE-tubing, and PTFE-diaphragm head types
• Dual independent controls: dedicated speed adjustment knob and separate power toggle—preserving user-defined speed settings during power cycling
• Integrated 3-digit LED display showing real-time rotational speed and motor direction—optimized for visibility under standard lab lighting conditions
• 4–20 mA analog interface for remote speed modulation and start/stop command integration into PLC-controlled or SCADA-managed systems
• IP33-rated enclosure—providing protection against vertically falling water droplets and solid objects ≥2.5 mm, suitable for general-purpose lab environments with occasional splashes or humidity exposure
• Compliance-ready design: conforms to ISO 9001:2000 quality management standards; certified to ETL (UL 61010-1) and CE (EN 61000-6-2, EN 61000-6-4) electromagnetic compatibility and safety directives

Sample Compatibility & Compliance

The 07528-30 drive itself does not contact fluids—fluid path integrity is defined by tubing and pump head selection. It accommodates a broad spectrum of chemically resistant tubing materials—including Tygon® LFL (low-permeation fluoropolymer-lined), Pharmed® BPT (biocompatible thermoplastic elastomer), platinum-cured silicone (USP Class VI, FDA-compliant), and fully fluorinated PTFE-lined or PTFE-diaphragm configurations. When paired with certified tubing and appropriate pump heads (e.g., 77250-62 High-Pressure Head or 07090-42 PTFE Diaphragm Head), the system meets requirements for GLP/GMP-regulated workflows involving aggressive solvents, strong acids/bases, or high-purity biological buffers. While the drive lacks built-in 21 CFR Part 11 audit trail functionality, its analog I/O and stable speed repeatability support integration into validated systems where electronic records are managed externally.

Software & Data Management

The 07528-30 operates as a standalone analog-controlled instrument without embedded firmware or proprietary software. All operational parameters—including speed, direction, and run state—are managed locally via tactile membrane keypad or remotely via 4–20 mA signal. For data logging or system-level automation, integration is achieved through third-party DAQ hardware or programmable logic controllers (PLCs) using standardized current-loop signaling. No onboard memory or USB/Ethernet connectivity is provided—ensuring electromagnetic robustness and eliminating cybersecurity attack surfaces common in networked lab devices. This architecture aligns with laboratories prioritizing deterministic control, long-term calibration stability, and regulatory traceability via external validation documentation rather than embedded software validation.

Applications

• Continuous feed of culture media, buffers, or inducers in bioreactor and chemostat systems
• Accurate metering of reagents in automated titration, ICP-MS sample introduction, or HPLC mobile phase blending
• Corrosive fluid transfer in wet chemistry labs—especially when configured with PTFE-diaphragm heads and fluoropolymer tubing
• Multi-stream proportional blending for formulation development or reaction quenching protocols
• Low-shear pumping of shear-sensitive biologics (e.g., viral vectors, exosomes) using large-bore, low-compression tubing configurations
• Environmental monitoring—sampling from wells, streams, or wastewater lines with chemically inert tubing and high-suction-capacity heads
• Process validation studies requiring documented flow reproducibility over extended durations (e.g., >100 hr continuous operation)

FAQ

What is the maximum number of pump heads supported by the 07528-30 drive?
The 07528-30 drive is mechanically and electrically rated for up to four pump heads mounted in parallel—each operating at identical speed but with independent tubing loading and pressure characteristics.
Can the 07528-30 be integrated into a GMP-compliant manufacturing environment?
Yes—when paired with appropriate tubing (e.g., USP Class VI silicone or PTFE), validated pump heads, and external documentation of installation qualification (IQ), operational qualification (OQ), and performance qualification (PQ), it satisfies core GMP fluid-handling requirements for non-sterile and sterile auxiliary operations.
Does the drive support variable-speed programming or ramp profiles?
No—the 07528-30 provides only manual or analog-setpoint speed control. Programmable ramping, timed sequences, or multi-step profiles require external PLC or motion controller interfacing via the 4–20 mA input.
What tubing sizes are compatible with the 07528-30 when used with an Easy-Load 3 pump head?
With the 77800-60 Easy-Load 3 head, tubing sizes 13#, 14#, 16#, 25#, 17#, and 18# (ID 0.8–8.0 mm) are supported; with the 77200-62 Easy-Load II head, sizes 15#, 24#, 35#, and 36# (ID 4.8–9.6 mm) are supported.
Is the drive suitable for high-pressure applications such as HPLC solvent delivery?
Not directly—the L/S platform is designed for low-to-medium pressure applications (typically ≤10.2 bar peak with high-performance heads). It is not rated for sustained backpressures above 5 bar typical of analytical HPLC systems; use is recommended for preparative, dilution, or auxiliary fluid paths instead.